Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 2, 2006, Pages

  Sun, Xiaowei ^a   Ku, David D ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Acetylcholine; Endothelium dependent relaxation; Heart failure; Monocrotaline; Nitric oxide

Indexed keywords

ACETYLCHOLINE; ARGININE METHYL ESTER; MONOCROTALINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ENZYME INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE DONOR; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; HEART HYPERTROPHY; HEART RIGHT VENTRICLE; HEART VENTRICLE SEPTUM; LEFT CORONARY ARTERY; LUNG PRESSURE; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; RIGHT CORONARY ARTERY; VASOCONSTRICTION; VASODILATATION; ANIMAL; CHEMICALLY INDUCED DISORDER; CORONARY BLOOD VESSEL; DRUG EFFECT; HEART RIGHT VENTRICLE HYPERTROPHY; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ACETYLCHOLINE; ANIMALS; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MONOCROTALINE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 33644869494     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00647.2005     Document Type: Article

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