Protein kinase C-ζ regulation of GLUT4 translocation through actin remodeling in CHO cells

Journal of Molecular Medicine

Volumn 85, Issue 8, 2007, Pages 851-861

  Liu, Xiao Jun ^a   Yang, Chang ^a   Gupta, Nishith ^b   Zuo, Jin ^a   Chang, Yong Sheng ^a   Fang, Fu De ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Actin cytoskeleton; Glucose transporter 4; Insulin; Protein kinase C

Indexed keywords

ACTIN; GLUCOSE TRANSPORTER 4; INSULIN; LATRUNCULIN B; PROTEIN KINASE C; PROTEIN KINASE C ZETA;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STIMULATION; CHO CELL; CONTROLLED STUDY; CYTOSKELETON; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GLUCOSE TRANSPORT; NONHUMAN; ONCOGENE MYC; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN TRANSPORT;

ACTINS; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPLASM; CYTOSKELETON; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; GREEN FLUORESCENT PROTEINS; IMMUNOBLOTTING; INSULIN; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; THIAZOLIDINES; THREONINE; TRANSFECTION;

EID: 34447504365     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-007-0232-z     Document Type: Article

References (35)

1. Watson RT, Kanzaki M, Pessin JE (2004) Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr Rev 25:177-204
2. Kanzaki M (2006) Insulin receptor signals regulating GLUT4 translocation and actin dynamics. Endocr J 53(3):267-293
3. He A, Liu X, Liu L, Chang Y, Fang F (2007) How many signals impinge on GLUT4 activation by insulin? Cell Signal 19:1-7
4. Ramaekers FC, Bosman FT (2004) The cytoskeleton and disease. J Pathol 204:351-354
5. Rudich A, Klip A (2003) Push/pull mechanisms of GLUT4 traffic in muscle cells. Acta Physiol Scand 178:297-308
6. Liu WS, Heckman CA (1998) The sevenfold way of PKC regulation. Cell Signal 10:529-542
7. Larsson C (2006) Protein kinase C and the regulation of the actin cytoskeleton. Cell Signal 18:276-284
8. Farese RV (2002) Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states. Am J Physiol Endocrinol Metab 283:E1-E11
9. Liu LZ, Zhao HL, Zuo J, Ho SK, Chan JC, Meng Y, Fang FD, Tong PC (2006) Protein kinase Czeta mediates insulin-induced glucose transport through actin remodeling in L6 muscle cells. Mol Biol Cell 17:2322-2330
10. Bogan JS, Mckee AE, Lodish HF (2001) Insulin-responsive compartments containing GLUT4 in 3T3-L1 and CHO cells: regulation by amino acid concentrations. Mol Cell Biol 21:4785-4806
11. Ijuin T, Takenawa T (2003) SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation. Mol Cell Biol 23:1209-1220
12. Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi K, Shiota H, Ebina Y (2003) Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions. J Biol Chem 278:28312-28323
13. Subtil A, Lampson MA, Keller SR, McGraw TE (2000) Characterization of the insulin-regulated endocytic recycling mechanism in 3T3-L1 adipocytes using a novel reporter molecule. J Biol Chem 275:4787-4795
14. Kanai F, Nishioka Y, Hayashi H, Kamohara S, Todaka M, Ebina Y (1993) Direct demonstration of insulin-induced GLUT4 translocation to the surface of intact cells by insertion of a c-myc epitope into an exofacial GLUT4 domain. J Biol Chem 268:14523-14526
15. Di Liberto G, Dallot E, Eude-Le Parco I, Cabrol D, Ferre F, Breuiller-Fouche M (2003) A critical role for PKCζ in endothelin-1-induced uterine contractions at the end of pregnancy. Am J Physiol Cell Physiol 285:C599-607
16. Eyster CA, Duggins QS, Olson AL (2005) Expression of constitutively active Akt/Protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton. J Biol Chem 280:17978-17985
17. Standaert ML, Bandyopadhyay G, Perez L, Price D, Galloway L, Poklepovic A, Sajan MP, Cenni V, Sirri A, Moscat J, Toker A, Farese RV (1999) Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation- dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes. J Biol Chem 274:25308-25316
18. Bandyopadhyay G, Standaert ML, Sajan MP, Karnitz LM, Cong L, Quon MJ, Farese RV (1999) Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta. Mol Endocrinol 13:1766-1772
19. Sbrissa D, Ikonomov OC, Strakova J, Shisheva A (2004) Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation. Endocrinology 145:4853-4865
20. Kanzaki M, Pessin JE (2001) Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling. J Biol Chem 276:42436-42444
21. Dlugosz JA, Munk S, Ispanovic E, Goldberg HJ, Whiteside CI (2002) Mesangial cell filamentous actin disassembly and hypocontractility in high glucose are mediated by PKC-zeta. Am J Physiol Renal Physiol 282:F151-F163
22. Liu XJ, He AB, Chang YS, Fang FD (2006) Atypical protein kinase C in glucose metabolism. Cell Signal 18:2071-2076
23. Khayat ZA, Tong P, Yaworsky K, Bloch RJ, Klip A (2000) Insulin-induced actin filament remodeling colocalizes actin with phosphatidylinositol 3-kinase and GLUT4 in L6 myotubes. J Cell Sci 113:279-290
24. Brozinick JT Jr, Hawkins ED, Strawbridge AB, Elmendorf JS (2004) Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues. J Biol Chem 279:40699-40706
25. Liu L, Jedrychowski MP, Gygi SP, Pilch PF (2006) Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes. Mol Biol Cell 17:4249-4256
26. Kanzaki M, Mora S, Hwang JB, Saltiel AR, Pessin JE (2004) Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways. J Cell Biol 164:279-290
27. Mitra P, Zheng X, Czech MP (2004) RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin. J Biol Chem 279:37431-37435
28. Sajan MP, Rivas J, Li P, Standaert ML, Farese RV (2006) Repletion of atypical protein kinase C following RNA interference-mediated depletion restores insulin-stimulated glucose transport. J Biol Chem 281:17466-17473
29. Etgen GJ, Valasek KM, Broderick CL, Miller AR (1999) In vivo adenoviral delivery of recombinant human protein kinase Cζ stimulates glucose transport activity in rat skeletal muscle. J Biol Chem 274:22139-22142
30. Doornbos RP, Theelen M, van der Hoeven PC, van Blitterswijk WJ, Verkleij AJ, van Bergen en Henegouwen PM (1999) Protein kinase Cζ is a negative regulator of protein kinase B activity. J Biol Chem 274:8589-8596
31. Huang J, Imamura T, Babendure JL, Lu JC, Olefsky JM (2005) Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem 280:42300-42306
32. Jiang ZY, Chawla A, Bose A, Way M, Czech MP (2002) A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP/Arp2/3/F-actin required for GLUT4 glucose transporter recycling. J Biol Chem 277:509-515
33. Leinweber B, Parissenti AM, Gallant C, Gangopadhyay SS, Kirwan-Rhude A, Leavis PC, Morgan KG (2000) Regulation of protein kinase C by the cytoskeletal protein calponin. J Biol Chem 275:40329-40336
34. Patil SB, Pawar MD, Bitar KN (2004) Direct association and translocation of PKC-alpha with calponin. Am J Physiol Gastrointest Liver Physiol 286:G954-G963
35. Even-Faitelson L, Ravid S (2006) PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assembly. Mol Biol Cell 17:2869-2881