Insulin-induced actin filament remodeling colocalizes actin with phosphatidylinositol 3-kinase and GLUT4 in L6 myotubes

Journal of Cell Science

Volumn 113, Issue 2, 2000, Pages 279-290

  Khayat, Zayna A ^a,b   Tong, Peter ^a,d   Yaworsky, Karen ^a,b   Bloch, Robert J ^c   Klip, Amira ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Actin cytoskeleton; GLUT4; Insulin; Phosphatidylinositol 3 kinase

Indexed keywords

ACTIN; AMINOPEPTIDASE; CYTOCHALASIN D; GLUCOSE TRANSPORTER; INSULIN; LATRUNCULIN B; PHALLOIDIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ACTIN FILAMENT; ARTICLE; ENZYME SUBUNIT; IMMUNOHISTOCHEMISTRY; MYOTUBE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CELL MEMBRANE; CYTOSKELETON; GLUCOSE TRANSPORTER TYPE 4; INSULIN; MODELS, BIOLOGICAL; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLES; ORGANELLES; RAC GTP-BINDING PROTEINS; RATS;

EID: 0033962410     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Adams, R. J. P. and Pollard, T. D. (1986). Propulsion of organelles isolated from Acanthamoeba along actin filaments by myosin-I. Nature 322, 754-756.
2. Castellino, F., Heuser, J., Marchetti, S., Bruno, B. and Luini, A. (1992). Glucocorticoid stabilization of actin filaments: a possible mechanism for inhibition of corticotropin release. Proc. Natl. Acad. Sci. USA 89, 3775-3779.
3. Cheatham, B., Vlahos, C. J., Cheatham, L., Wang, L., Blenis, J. and Kahn, C. R. (1994). Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell. Biol. 14, 4902-4911.
4. Clark, S. F., Martin, S., Carozzi, A. J., Hill, M. M. and James, D. E. (1998). Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton. J. Cell Biol. 140, 1211-1225.
5. Clodi, M., Vollenweider, P., Klarlund, J., Nakashima, N., Martin, S., Czech, M. P. and Olefsky, J. M. (1998). Effects of general receptor for phosphoinositides 1 on insulin and insulin-like growth factor I-induced cytoskeletal rearrangement, glucose transporter-4 translocation, and deoxyribonucleic acid synthesis. Endocrinology 139, 4984-4990.
6. Cooper, J. A. (1987). Effects of cytochalasins and phalloidin on actin. J. Cell Biol. 105, 1473-1478.
7. Corcoran, S. L., Hayes, N. V., Nicol, S., Baines, A. J. and Thomas, H. M. (1998). Intracellular localisation of beta I sigma 2 spectrin with GLUT4 vesicles. Biochem. Soc. Trans. 26, S107.
8. Corcoran, S. L., Wylie, P. G., Hayes, N. V., Baines, A. J. and Thomas, H. M. (1997). Characterisation of spectrin isoforms associated with GLUT4. Biochem. Soc. Trans. 25, S483.
9. Dancker, P., Low, I., Hasselbach, W. and Wieland, T. (1975). Interaction of actin with phalloidin: polymerization and stabilization of F-actin. Biochim. Biophys. Acta 400, 407-414.
10. Zhang, S., Han, J., Sells, M. A., Chernoff, J., Knaus, U. G., Ulevitch, R. J. and Bokoch, G. M. (1995). Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J. Biol. Chem. 270, 23934-23936.