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Volumn 1160, Issue 1, 2007, Pages 47-57

BDNF transgene improves ataxic and motor behaviors in stargazer mice

Author keywords

BDNF; Cerebellar ataxia; Footprint analysis; Motor behavior; Stargazer; Transgene

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

EID: 34447338602     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.05.048     Document Type: Article
Times cited : (18)

References (45)
  • 1
    • 0032464810 scopus 로고    scopus 로고
    • Impaired eye-blink conditioning in waggler, a mutant mouse with cerebellar BDNF deficiency
    • Bao S., Chen L., Qiao X., Knusel B., and Thompson R.F. Impaired eye-blink conditioning in waggler, a mutant mouse with cerebellar BDNF deficiency. Learn. Mem. 5 (1998) 355-364
    • (1998) Learn. Mem. , vol.5 , pp. 355-364
    • Bao, S.1    Chen, L.2    Qiao, X.3    Knusel, B.4    Thompson, R.F.5
  • 2
    • 0032848464 scopus 로고    scopus 로고
    • Transgenic brain-derived neurotrophic factor modulates a developing cerebellar inhibitory synapse
    • Bao S., Chen L., Qiao X., and Thompson R.F. Transgenic brain-derived neurotrophic factor modulates a developing cerebellar inhibitory synapse. Learn. Mem. 6 (1999) 276-283
    • (1999) Learn. Mem. , vol.6 , pp. 276-283
    • Bao, S.1    Chen, L.2    Qiao, X.3    Thompson, R.F.4
  • 4
    • 35148829836 scopus 로고    scopus 로고
    • Carter, R.J., Morton, A.J., Dunnett, S.B., 2001. Motor coordination and balance in rodents. Current Protocols in Neuroscience. Vol. 8. John Wiley & Sons, Inc., New York, pp. 1-14.
  • 5
    • 27744450800 scopus 로고    scopus 로고
    • Changes in synaptic structure underlie the developmental speeding of AMPA receptor-mediated EPSCs
    • Cathala L., Holderith N.B., Nusser Z., Digregorio D.A., and Cull-Candy S.G. Changes in synaptic structure underlie the developmental speeding of AMPA receptor-mediated EPSCs. Nat. Neurosci. 8 (2005) 1310-1318
    • (2005) Nat. Neurosci. , vol.8 , pp. 1310-1318
    • Cathala, L.1    Holderith, N.B.2    Nusser, Z.3    Digregorio, D.A.4    Cull-Candy, S.G.5
  • 6
    • 0032694356 scopus 로고    scopus 로고
    • Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel gamma subunit
    • Chen L., Bao S., Qiao X., and Thompson R.F. Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel gamma subunit. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 12132-12137
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 12132-12137
    • Chen, L.1    Bao, S.2    Qiao, X.3    Thompson, R.F.4
  • 8
    • 0032765275 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex
    • Croll S.D., Suri C., Compton D.L., Simmons M.V., Yancopoulos G.D., Lindsay R.M., Wiegand S.J., Rudge J.S., and Scharfman H.E. Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience 93 (1999) 1491-1506
    • (1999) Neuroscience , vol.93 , pp. 1491-1506
    • Croll, S.D.1    Suri, C.2    Compton, D.L.3    Simmons, M.V.4    Yancopoulos, G.D.5    Lindsay, R.M.6    Wiegand, S.J.7    Rudge, J.S.8    Scharfman, H.E.9
  • 9
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors P., Lee K.F., and Jaenisch R. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368 (1994) 147-150
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.F.2    Jaenisch, R.3
  • 10
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., and Lu B. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381 (1996) 706-709
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.D.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 12
    • 0033565945 scopus 로고    scopus 로고
    • Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer
    • Hashimoto K., Fukaya M., Qiao X., Sakimura K., Watanabe M., and Kano M. Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. J. Neurosci. 19 (1999) 6027-6036
    • (1999) J. Neurosci. , vol.19 , pp. 6027-6036
    • Hashimoto, K.1    Fukaya, M.2    Qiao, X.3    Sakimura, K.4    Watanabe, M.5    Kano, M.6
  • 13
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • Hofer M., Pagliusi S.R., Hohn A., Leibrock J., and Barde Y.A. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J. 9 (1990) 2459-2464
    • (1990) EMBO J. , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, J.4    Barde, Y.A.5
  • 14
    • 0025883295 scopus 로고
    • BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF
    • Isackson P.J., Huntsman M.M., Murray K.D., and Gall C.M. BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron 6 (1991) 937-948
    • (1991) Neuron , vol.6 , pp. 937-948
    • Isackson, P.J.1    Huntsman, M.M.2    Murray, K.D.3    Gall, C.M.4
  • 15
    • 0028351190 scopus 로고
    • Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
    • Jones K.R., Farinas I., Backus C., and Reichardt L.F. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76 (1994) 989-999
    • (1994) Cell , vol.76 , pp. 989-999
    • Jones, K.R.1    Farinas, I.2    Backus, C.3    Reichardt, L.F.4
  • 16
    • 3342924056 scopus 로고    scopus 로고
    • Abnormal motor behavior and vestibular dysfunction in the stargazer mouse mutant
    • Khan Z., Carey J., Park H.J., Lehar M., Lasker D., and Jinnah H.A. Abnormal motor behavior and vestibular dysfunction in the stargazer mouse mutant. Neuroscience 127 (2004) 785-796
    • (2004) Neuroscience , vol.127 , pp. 785-796
    • Khan, Z.1    Carey, J.2    Park, H.J.3    Lehar, M.4    Lasker, D.5    Jinnah, H.A.6
  • 17
    • 0028343266 scopus 로고
    • Role of neurotrophins in mouse neuronal development
    • Klein R. Role of neurotrophins in mouse neuronal development. FASEB J. 8 (1994) 738-744
    • (1994) FASEB J. , vol.8 , pp. 738-744
    • Klein, R.1
  • 20
    • 33747724678 scopus 로고    scopus 로고
    • Stargazer - a mouse to seize!
    • Letts V.A. Stargazer - a mouse to seize!. Epilepsy Curr. 5 (2005) 161-165
    • (2005) Epilepsy Curr. , vol.5 , pp. 161-165
    • Letts, V.A.1
  • 23
    • 0029099174 scopus 로고
    • Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors
    • Levine E.S., Dreyfus C.F., Black I.B., and Plummer M.R. Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 8074-8077
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 8074-8077
    • Levine, E.S.1    Dreyfus, C.F.2    Black, I.B.3    Plummer, M.R.4
  • 24
    • 0027423233 scopus 로고
    • Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity
    • Lindholm D., Dechant G., Heisenberg C.P., and Thoenen H. Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur. J. Neurosci. 5 (1993) 1455-1464
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 1455-1464
    • Lindholm, D.1    Dechant, G.2    Heisenberg, C.P.3    Thoenen, H.4
  • 25
    • 33751190286 scopus 로고    scopus 로고
    • Stargazin mutation impairs cerebellar synaptogenesis, synaptic maturation and synaptic protein distribution
    • Meng H., Walker N., Su Y., and Qiao X. Stargazin mutation impairs cerebellar synaptogenesis, synaptic maturation and synaptic protein distribution. Brain Res. 1124 (2006) 197-207
    • (2006) Brain Res. , vol.1124 , pp. 197-207
    • Meng, H.1    Walker, N.2    Su, Y.3    Qiao, X.4
  • 26
    • 0031813534 scopus 로고    scopus 로고
    • A role for BDNF in early postnatal rat vestibular epithelia maturation: implication of supporting cells
    • Montcouquiol M., Valat J., Travo C., and Sans A. A role for BDNF in early postnatal rat vestibular epithelia maturation: implication of supporting cells. Eur. J. Neurosci. 10 (1998) 598-606
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 598-606
    • Montcouquiol, M.1    Valat, J.2    Travo, C.3    Sans, A.4
  • 27
    • 0034658022 scopus 로고    scopus 로고
    • Detection and localization of BDNF in vestibular nuclei during the postnatal development of the rat
    • Montcouquiol M.E., Sans N.A., Travo C., Sans A., and Valat J. Detection and localization of BDNF in vestibular nuclei during the postnatal development of the rat. NeuroReport 11 (2000) 1401-1405
    • (2000) NeuroReport , vol.11 , pp. 1401-1405
    • Montcouquiol, M.E.1    Sans, N.A.2    Travo, C.3    Sans, A.4    Valat, J.5
  • 28
    • 33644674232 scopus 로고    scopus 로고
    • Auxiliary subunits assist AMPA-type glutamate receptors
    • Nicoll R.A., Tomita S., and Bredt D.S. Auxiliary subunits assist AMPA-type glutamate receptors. Science 311 (2006) 1253-1256
    • (2006) Science , vol.311 , pp. 1253-1256
    • Nicoll, R.A.1    Tomita, S.2    Bredt, D.S.3
  • 29
    • 0025010056 scopus 로고
    • Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures
    • Noebels J.L., Qiao X., Bronson R.T., Spencer C., and Davisson M.T. Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy Res. 7 (1990) 129-135
    • (1990) Epilepsy Res. , vol.7 , pp. 129-135
    • Noebels, J.L.1    Qiao, X.2    Bronson, R.T.3    Spencer, C.4    Davisson, M.T.5
  • 30
    • 15044360385 scopus 로고    scopus 로고
    • Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus
    • Otal R., Martinez A., and Soriano E. Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus. Cell Tissue Res. 319 (2005) 349-358
    • (2005) Cell Tissue Res. , vol.319 , pp. 349-358
    • Otal, R.1    Martinez, A.2    Soriano, E.3
  • 31
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • Patterson S.L., Grover L.M., Schwartzkroin P.A., and Bothwell M. Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9 (1992) 1081-1088
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.L.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 32
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson S.L., Abel T., Deuel T.A., Martin K.C., Rose J.C., and Kandel E.R. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16 (1996) 1137-1145
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 33
    • 0033564051 scopus 로고    scopus 로고
    • Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice
    • Pozzo-Miller L.D., Gottschalk W., Zhang L., McDermott K., Du J., Gopalakrishnan R., Oho C., Sheng Z.H., and Lu B. Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice. J. Neurosci. 19 (1999) 4972-4983
    • (1999) J. Neurosci. , vol.19 , pp. 4972-4983
    • Pozzo-Miller, L.D.1    Gottschalk, W.2    Zhang, L.3    McDermott, K.4    Du, J.5    Gopalakrishnan, R.6    Oho, C.7    Sheng, Z.H.8    Lu, B.9
  • 34
    • 1642494621 scopus 로고    scopus 로고
    • Nonchannel functions of the calcium channel gamma subunit: insight from research on the stargazer mutant
    • Qiao X., and Meng H. Nonchannel functions of the calcium channel gamma subunit: insight from research on the stargazer mutant. J. Bioenerg. Biomembr. 35 (2003) 661-670
    • (2003) J. Bioenerg. Biomembr. , vol.35 , pp. 661-670
    • Qiao, X.1    Meng, H.2
  • 35
    • 0030069131 scopus 로고    scopus 로고
    • Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia
    • Qiao X., Hefti F., Knusel B., and Noebels J.L. Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia. J. Neurosci. 16 (1996) 640-648
    • (1996) J. Neurosci. , vol.16 , pp. 640-648
    • Qiao, X.1    Hefti, F.2    Knusel, B.3    Noebels, J.L.4
  • 36
    • 0032171561 scopus 로고    scopus 로고
    • Cerebellar brain-derived neurotrophic factor-TrkB defect associated with impairment of eyeblink conditioning in Stargazer mutant mice
    • Qiao X., Chen L., Gao H., Bao S., Hefti F., Thompson R.F., and Knusel B. Cerebellar brain-derived neurotrophic factor-TrkB defect associated with impairment of eyeblink conditioning in Stargazer mutant mice. J. Neurosci. 18 (1998) 6990-6999
    • (1998) J. Neurosci. , vol.18 , pp. 6990-6999
    • Qiao, X.1    Chen, L.2    Gao, H.3    Bao, S.4    Hefti, F.5    Thompson, R.F.6    Knusel, B.7
  • 37
    • 0035341088 scopus 로고    scopus 로고
    • Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain-derived neurotrophic factor
    • Qiao X., Suri C., Knusel B., and Noebels J.L. Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain-derived neurotrophic factor. J. Neurosci. Res. 64 (2001) 268-276
    • (2001) J. Neurosci. Res. , vol.64 , pp. 268-276
    • Qiao, X.1    Suri, C.2    Knusel, B.3    Noebels, J.L.4
  • 38
    • 9744248623 scopus 로고    scopus 로고
    • Phenotype of cerebellar glutamatergic neurons is altered in stargazer mutant mice lacking brain-derived neurotrophic factor mRNA expression
    • Richardson C.A., and Leitch B. Phenotype of cerebellar glutamatergic neurons is altered in stargazer mutant mice lacking brain-derived neurotrophic factor mRNA expression. J. Comp. Neurol. 481 (2005) 145-159
    • (2005) J. Comp. Neurol. , vol.481 , pp. 145-159
    • Richardson, C.A.1    Leitch, B.2
  • 39
    • 0030867989 scopus 로고    scopus 로고
    • Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning
    • Schwartz P.M., Borghesani P.R., Levy R.L., Pomeroy S.L., and Segal R.A. Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning. Neuron 19 (1997) 269-281
    • (1997) Neuron , vol.19 , pp. 269-281
    • Schwartz, P.M.1    Borghesani, P.R.2    Levy, R.L.3    Pomeroy, S.L.4    Segal, R.A.5
  • 40
    • 0027081202 scopus 로고
    • Changes in neurotrophin responsiveness during the development of cerebellar granule neurons
    • Segal R.A., Takahashi H., and McKay R.D. Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. Neuron 9 (1992) 1041-1052
    • (1992) Neuron , vol.9 , pp. 1041-1052
    • Segal, R.A.1    Takahashi, H.2    McKay, R.D.3
  • 41
    • 0028331599 scopus 로고
    • Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene
    • Smeyne R.J., Klein R., Schnapp A., Long L.K., Bryant S., Lewin A., Lira S.A., and Barbacid M. Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368 (1994) 246-249
    • (1994) Nature , vol.368 , pp. 246-249
    • Smeyne, R.J.1    Klein, R.2    Schnapp, A.3    Long, L.K.4    Bryant, S.5    Lewin, A.6    Lira, S.A.7    Barbacid, M.8
  • 42
    • 4444260120 scopus 로고    scopus 로고
    • BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system
    • Tolwani R.J., Cosgaya J.M., Varma S., Jacob R., Kuo L.E., and Shooter E.M. BDNF overexpression produces a long-term increase in myelin formation in the peripheral nervous system. J. Neurosci. Res. 77 (2004) 662-669
    • (2004) J. Neurosci. Res. , vol.77 , pp. 662-669
    • Tolwani, R.J.1    Cosgaya, J.M.2    Varma, S.3    Jacob, R.4    Kuo, L.E.5    Shooter, E.M.6
  • 45
    • 0025084077 scopus 로고
    • Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors
    • Zafra F., Hengerer B., Leibrock J., Thoenen H., and Lindholm D. Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J. 9 (1990) 3545-3550
    • (1990) EMBO J. , vol.9 , pp. 3545-3550
    • Zafra, F.1    Hengerer, B.2    Leibrock, J.3    Thoenen, H.4    Lindholm, D.5


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