-
2
-
-
21844450244
-
Intracellular signalling controlling integrin activation in lymphocytes
-
Kinashi T. Intracellular signalling controlling integrin activation in lymphocytes. Nat Rev Immunol 2005 5:546 559.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 546-559
-
-
Kinashi, T.1
-
4
-
-
4043114185
-
Cutting edge: LFA-1 integrin-dependent T cell adhesion is regulated by both ag specificity and sensitivity
-
Mueller KL, Daniels MA, Felthauser A, Kao C, Jameson SC, Shimizu Y. Cutting edge: LFA-1 integrin-dependent T cell adhesion is regulated by both ag specificity and sensitivity. J Immunol 2004 173:2222 2226.
-
(2004)
J Immunol
, vol.173
, pp. 2222-2226
-
-
Mueller, K.L.1
Daniels, M.A.2
Felthauser, A.3
Kao, C.4
Jameson, S.C.5
Shimizu, Y.6
-
5
-
-
0031952651
-
Are changes in integrin affinity and conformation overemphasized?
-
Bazzoni G, Hemler ME. Are changes in integrin affinity and conformation overemphasized? Trends Biochem Sci 1998 23:30 34.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 30-34
-
-
Bazzoni, G.1
Hemler, M.E.2
-
6
-
-
0028887998
-
Multiple kinases mediate T-cell-receptor signaling
-
Howe LR, Weiss A. Multiple kinases mediate T-cell-receptor signaling. Trends Biochem Sci 1995 20:59 64.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 59-64
-
-
Howe, L.R.1
Weiss, A.2
-
7
-
-
0028288927
-
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
-
Chan AC, Desai DM, Weiss A. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol 1994 12:555 592.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.M.2
Weiss, A.3
-
8
-
-
0037392883
-
Positive and negative regulation of T-cell activation through kinases and phosphatases
-
Mustelin T, Tasken K. Positive and negative regulation of T-cell activation through kinases and phosphatases. Biochem J 2003 371:15 27.
-
(2003)
Biochem J
, vol.371
, pp. 15-27
-
-
Mustelin, T.1
Tasken, K.2
-
9
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994 76:263 274.
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
10
-
-
0033047309
-
Integration of T cell receptor-dependent signaling pathways by adapter proteins
-
Clements JL, Boerth NJ, Lee JR, Koretzky GA. Integration of T cell receptor-dependent signaling pathways by adapter proteins. Annu Rev Immunol 1999 17:89 108.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 89-108
-
-
Clements, J.L.1
Boerth, N.J.2
Lee, J.R.3
Koretzky, G.A.4
-
11
-
-
3543071011
-
Transmembrane adaptor proteins: Organizers of immunoreceptor signalling
-
Horejsi V, Zhang W, Schraven B. Transmembrane adaptor proteins: organizers of immunoreceptor signalling. Nat Rev Immunol 2004 4:603 616.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 603-616
-
-
Horejsi, V.1
Zhang, W.2
Schraven, B.3
-
12
-
-
0037318720
-
Adaptors as central mediators of signal transduction in immune cells
-
Jordan MS, Singer AL, Koretzky GA. Adaptors as central mediators of signal transduction in immune cells. Nat Immunol 2003 4:110 116.
-
(2003)
Nat Immunol
, vol.4
, pp. 110-116
-
-
Jordan, M.S.1
Singer, A.L.2
Koretzky, G.A.3
-
13
-
-
33244490746
-
SLP76 and SLP65: Complex regulation of signalling in lymphocytes and beyond
-
Koretzky GA, Abtahian F, Silverman MA. SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond. Nat Rev Immunol 2006 6:67 78.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 67-78
-
-
Koretzky, G.A.1
Abtahian, F.2
Silverman, M.A.3
-
14
-
-
0032142953
-
LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
-
Zhang W, Trible RP, Samelson LE. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 1998 9:239 246.
-
(1998)
Immunity
, vol.9
, pp. 239-246
-
-
Zhang, W.1
Trible, R.P.2
Samelson, L.E.3
-
15
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998 92:83 92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
16
-
-
0035525572
-
Positive and negative regulation of T-cell activation by adaptor proteins
-
Koretzky GA, Myung PS. Positive and negative regulation of T-cell activation by adaptor proteins. Nat Rev Immunol 2001 1:95 107.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 95-107
-
-
Koretzky, G.A.1
Myung, P.S.2
-
17
-
-
0028928422
-
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
-
Jackman JK, et al. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 1995 270:7029 7032.
-
(1995)
J Biol Chem
, vol.270
, pp. 7029-7032
-
-
Jackman, J.K.1
-
18
-
-
0032555211
-
FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells
-
Liu J, Kang H, Raab M, da Silva AJ, Kraeft SK, Rudd CE. FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. Proc Natl Acad Sci USA 1998 95:8779 8784.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8779-8784
-
-
Liu, J.1
Kang, H.2
Raab, M.3
Da Silva, A.J.4
Kraeft, S.K.5
Rudd, C.E.6
-
19
-
-
0032475935
-
Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130
-
Marie-Cardine A, Hendricks-Taylor LR, Boerth NJ, Zhao H, Schraven B, Koretzky GA. Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130. J Biol Chem 1998 273:25789 25795.
-
(1998)
J Biol Chem
, vol.273
, pp. 25789-25795
-
-
Marie-Cardine, A.1
Hendricks-Taylor, L.R.2
Boerth, N.J.3
Zhao, H.4
Schraven, B.5
Koretzky, G.A.6
-
20
-
-
0033523014
-
SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity
-
Fang N, Koretzky GA. SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity. J Biol Chem 1999 274:16206 16212.
-
(1999)
J Biol Chem
, vol.274
, pp. 16206-16212
-
-
Fang, N.1
Koretzky, G.A.2
-
21
-
-
0036199184
-
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells
-
Krawczyk C, et al. Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells. Immunity 2002 16:331 343.
-
(2002)
Immunity
, vol.16
, pp. 331-343
-
-
Krawczyk, C.1
-
22
-
-
18844449626
-
Vav-family proteins in T-cell signalling
-
Tybulewicz VL. Vav-family proteins in T-cell signalling. Curr Opin Immunol 2005 17:267 274.
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 267-274
-
-
Tybulewicz, V.L.1
-
23
-
-
0037323858
-
The role of Rap1 in integrin-mediated cell adhesion
-
Bos JL, et al. The role of Rap1 in integrin-mediated cell adhesion. Biochem Soc Trans 2003 31:83 86.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 83-86
-
-
Bos, J.L.1
-
24
-
-
15044359236
-
Linking Rap to cell adhesion
-
Bos JL. Linking Rap to cell adhesion. Curr Opin Cell Biol 2005 17:123 128.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 123-128
-
-
Bos, J.L.1
-
25
-
-
23944437624
-
Chemokine control of lymphocyte trafficking: A general overview
-
Stein JV, Nombela-Arrieta C. Chemokine control of lymphocyte trafficking: a general overview. Immunology 2005 116:1 12.
-
(2005)
Immunology
, vol.116
, pp. 1-12
-
-
Stein, J.V.1
Nombela-Arrieta, C.2
-
27
-
-
0037868184
-
Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine
-
Kremer KN, Humphreys TD, Kumar A, Qian NX, Hedin KE. Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine. J Immunol 2003 171:360 367.
-
(2003)
J Immunol
, vol.171
, pp. 360-367
-
-
Kremer, K.N.1
Humphreys, T.D.2
Kumar, A.3
Qian, N.X.4
Hedin, K.E.5
-
28
-
-
0034141993
-
Cutting edge: A novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration
-
Hunter AJ, Ottoson N, Boerth N, Koretzky GA, Shimizu Y. Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration. J Immunol 2000 164:1143 1147.
-
(2000)
J Immunol
, vol.164
, pp. 1143-1147
-
-
Hunter, A.J.1
Ottoson, N.2
Boerth, N.3
Koretzky, G.A.4
Shimizu, Y.5
-
29
-
-
33745907829
-
Lipid-binding hSH3 domains in immune cell adapter proteins
-
Heuer K, et al. Lipid-binding hSH3 domains in immune cell adapter proteins. J Mol Biol 2006 361:94 104.
-
(2006)
J Mol Biol
, vol.361
, pp. 94-104
-
-
Heuer, K.1
-
30
-
-
0030959305
-
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases
-
Musci MA, et al. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. J Biol Chem 1997 272:11674 11677.
-
(1997)
J Biol Chem
, vol.272
, pp. 11674-11677
-
-
Musci, M.A.1
-
31
-
-
0030737886
-
Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production
-
da Silva AJ, Li Z, de Vera C, Canto E, Findell P, Rudd CE. Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc Natl Acad Sci USA 1997 94:7493 7498.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7493-7498
-
-
Da Silva, A.J.1
Li, Z.2
De Vera, C.3
Canto, E.4
Findell, P.5
Rudd, C.E.6
-
32
-
-
0033213937
-
Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production
-
Veale M, et al. Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production. J Biol Chem 1999 274:28427 28435.
-
(1999)
J Biol Chem
, vol.274
, pp. 28427-28435
-
-
Veale, M.1
-
33
-
-
0033597929
-
FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells
-
Raab M, Kang H, da Silva A, Zhu X, Rudd CE. FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells. J Biol Chem 1999 274:21170 21179.
-
(1999)
J Biol Chem
, vol.274
, pp. 21170-21179
-
-
Raab, M.1
Kang, H.2
Da Silva, A.3
Zhu, X.4
Rudd, C.E.5
-
34
-
-
0034599541
-
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton
-
Krause M, Sechi AS, Konradt M, Monner D, Gertler FB, Wehland J. Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator- stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J Cell Biol 2000 149:181 194.
-
(2000)
J Cell Biol
, vol.149
, pp. 181-194
-
-
Krause, M.1
Sechi, A.S.2
Konradt, M.3
Monner, D.4
Gertler, F.B.5
Wehland, J.6
-
35
-
-
1842450344
-
Structure of a helically extended SH3 domain of the T cell adapter protein ADAP
-
Heuer K, Kofler M, Langdon G, Thiemke K, Freund C. Structure of a helically extended SH3 domain of the T cell adapter protein ADAP. Structure 2004 12:603 610.
-
(2004)
Structure
, vol.12
, pp. 603-610
-
-
Heuer, K.1
Kofler, M.2
Langdon, G.3
Thiemke, K.4
Freund, C.5
-
36
-
-
0035929128
-
Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap
-
Griffiths EK, et al. Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science 2001 293:2260 2263.
-
(2001)
Science
, vol.293
, pp. 2260-2263
-
-
Griffiths, E.K.1
-
37
-
-
0035929222
-
Coupling of the TCR to integrin activation by Slap-130/Fyb
-
Peterson EJ, et al. Coupling of the TCR to integrin activation by Slap-130/Fyb. Science 2001 293:2263 2265.
-
(2001)
Science
, vol.293
, pp. 2263-2265
-
-
Peterson, E.J.1
-
38
-
-
33646946230
-
Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection
-
Wu JN, et al. Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection. J Immunol 2006 176:6681 6689.
-
(2006)
J Immunol
, vol.176
, pp. 6681-6689
-
-
Wu, J.N.1
-
39
-
-
7244221321
-
ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation
-
Wang H, et al. ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation. J Exp Med 2004 200:1063 1074.
-
(2004)
J Exp Med
, vol.200
, pp. 1063-1074
-
-
Wang, H.1
-
40
-
-
33749172382
-
The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1
-
Kliche S, et al. The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. Mol Cell Biol 2006 26:7130 7144.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7130-7144
-
-
Kliche, S.1
-
41
-
-
0032540906
-
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
Clements JL, et al. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 1998 281:416 419.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
-
42
-
-
18244408051
-
Differential requirement for SLP-76 domains in T cell development and function
-
Myung PS, et al. Differential requirement for SLP-76 domains in T cell development and function. Immunity 2001 15:1011 1126.
-
(2001)
Immunity
, vol.15
, pp. 1011-1126
-
-
Myung, P.S.1
-
43
-
-
0037154235
-
Differential role of SLP-76 domains in T cell development and function
-
Kumar L, Pivniouk V, de la Fuente MA, Laouini D, Geha RS. Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci USA 2002 99:884 889.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 884-889
-
-
Kumar, L.1
Pivniouk, V.2
De La Fuente, M.A.3
Laouini, D.4
Geha, R.S.5
-
44
-
-
0034705291
-
Putting on the brakes: A negative regulatory function for Ena/VASP proteins in cell migration
-
Machesky LM. Putting on the brakes: a negative regulatory function for Ena/VASP proteins in cell migration. Cell 2000 101:685 688.
-
(2000)
Cell
, vol.101
, pp. 685-688
-
-
MacHesky, L.M.1
-
45
-
-
0345687479
-
Ena/VASP proteins: Regulators of the actin cytoskeleton and cell migration
-
Krause M, Dent EW, Bear JE, Loureiro JJ, Gertler FB. Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration. Annu Rev Cell Dev Biol 2003 19:541 564.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 541-564
-
-
Krause, M.1
Dent, E.W.2
Bear, J.E.3
Loureiro, J.J.4
Gertler, F.B.5
-
46
-
-
0035211279
-
Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis
-
Coppolino MG, et al. Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis. J Cell Sci 2001 114:4307 4318.
-
(2001)
J Cell Sci
, vol.114
, pp. 4307-4318
-
-
Coppolino, M.G.1
-
47
-
-
0035949507
-
Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: Differential involvement of the FYB SH3 domain
-
Geng L, Pfister S, Kraeft SK, Rudd CE. Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain. Proc Natl Acad Sci USA 2001 98:11527 11532.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11527-11532
-
-
Geng, L.1
Pfister, S.2
Kraeft, S.K.3
Rudd, C.E.4
-
48
-
-
0035930944
-
Adaptor ADAP (adhesion- and degranulation-promoting adaptor protein) regulates beta1 integrin clustering on mast cells
-
Geng L, Rudd C. Adaptor ADAP (adhesion- and degranulation-promoting adaptor protein) regulates beta1 integrin clustering on mast cells. Biochem Biophys Res Commun 2001 289:1135 1140.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 1135-1140
-
-
Geng, L.1
Rudd, C.2
-
49
-
-
2442700314
-
Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function
-
Wu JN, Jordan MS, Silverman MA, Peterson EJ, Koretzky GA. Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function. J Immunol 2004 172:6768 6774.
-
(2004)
J Immunol
, vol.172
, pp. 6768-6774
-
-
Wu, J.N.1
Jordan, M.S.2
Silverman, M.A.3
Peterson, E.J.4
Koretzky, G.A.5
-
50
-
-
33846893442
-
ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists
-
Kasirer-Friede A, et al. ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. Blood 2007 109:1018 1025.
-
(2007)
Blood
, vol.109
, pp. 1018-1025
-
-
Kasirer-Friede, A.1
-
51
-
-
33846031421
-
The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation
-
Suzuki J, Yamasaki S, Wu J, Koretzky GA, Saito T. The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation. Blood 2007 109:168 175.
-
(2007)
Blood
, vol.109
, pp. 168-175
-
-
Suzuki, J.1
Yamasaki, S.2
Wu, J.3
Koretzky, G.A.4
Saito, T.5
-
52
-
-
0030910820
-
Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes
-
Marie-Cardine A, Bruyns E, Eckerskorn C, Kirchgessner H, Meuer SC, Schraven B. Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes. J Biol Chem 1997 272:16077 16080.
-
(1997)
J Biol Chem
, vol.272
, pp. 16077-16080
-
-
Marie-Cardine, A.1
Bruyns, E.2
Eckerskorn, C.3
Kirchgessner, H.4
Meuer, S.C.5
Schraven, B.6
-
53
-
-
24344496065
-
Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM
-
Togni M, et al. Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM. Mol Cell Biol 2005 25:8052 8063.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8052-8063
-
-
Togni, M.1
-
54
-
-
0034659759
-
SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55
-
Kang H, Freund C, Duke-Cohan JS, Musacchio A, Wagner G, Rudd CE. SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55. EMBO J 2000 19:2889 2899.
-
(2000)
EMBO J
, vol.19
, pp. 2889-2899
-
-
Kang, H.1
Freund, C.2
Duke-Cohan, J.S.3
Musacchio, A.4
Wagner, G.5
Rudd, C.E.6
-
55
-
-
33744949265
-
Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein
-
Duke-Cohan JS, Kang H, Liu H, Rudd CE. Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein. J Biol Chem 2006 281:13743 13750.
-
(2006)
J Biol Chem
, vol.281
, pp. 13743-13750
-
-
Duke-Cohan, J.S.1
Kang, H.2
Liu, H.3
Rudd, C.E.4
-
56
-
-
21244492894
-
Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells
-
Huang Y, Norton DD, Precht P, Martindale JL, Burkhardt JK, Wange RL. Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells. J Biol Chem 2005 280:23576 23583.
-
(2005)
J Biol Chem
, vol.280
, pp. 23576-23583
-
-
Huang, Y.1
Norton, D.D.2
Precht, P.3
Martindale, J.L.4
Burkhardt, J.K.5
Wange, R.L.6
-
57
-
-
0037385961
-
SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates
-
Wang H, et al. SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates. Nat Immunol 2003 4:366 374.
-
(2003)
Nat Immunol
, vol.4
, pp. 366-374
-
-
Wang, H.1
-
58
-
-
22344434576
-
An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R
-
Jo EK, Wang H, Rudd CE. An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R. J Exp Med 2005 201:1733 1739.
-
(2005)
J Exp Med
, vol.201
, pp. 1733-1739
-
-
Jo, E.K.1
Wang, H.2
Rudd, C.E.3
-
59
-
-
0032508602
-
SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55
-
Marie-Cardine A, Verhagen AM, Eckerskorn C, Schraven B. SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55. FEBS Lett 1998 435:55 60.
-
(1998)
FEBS Lett
, vol.435
, pp. 55-60
-
-
Marie-Cardine, A.1
Verhagen, A.M.2
Eckerskorn, C.3
Schraven, B.4
-
60
-
-
0033793991
-
Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest
-
Curtis DJ, Jane SM, Hilton DJ, Dougherty L, Bodine DM, Begley CG. Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest. Exp Hematol 2000 28:1250 1259.
-
(2000)
Exp Hematol
, vol.28
, pp. 1250-1259
-
-
Curtis, D.J.1
Jane, S.M.2
Hilton, D.J.3
Dougherty, L.4
Bodine, D.M.5
Begley, C.G.6
-
61
-
-
0030812812
-
Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap1
-
Boussiotis VA, Freeman GJ, Berezovskaya A, Barber DL, Nadler LM. Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science 1997 278:124 128.
-
(1997)
Science
, vol.278
, pp. 124-128
-
-
Boussiotis, V.A.1
Freeman, G.J.2
Berezovskaya, A.3
Barber, D.L.4
Nadler, L.M.5
-
62
-
-
0036009116
-
Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
-
Sebzda E, Bracke M, Tugal T, Hogg N, Cantrell DA. Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat Immunol 2002 3:251 258.
-
(2002)
Nat Immunol
, vol.3
, pp. 251-258
-
-
Sebzda, E.1
Bracke, M.2
Tugal, T.3
Hogg, N.4
Cantrell, D.A.5
-
63
-
-
0034004457
-
Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
-
Katagiri K, Hattori M, Minato N, Irie S, Takatsu K, Kinashi T. Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase. Mol Cell Biol 2000 20:1956 1969.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1956-1969
-
-
Katagiri, K.1
Hattori, M.2
Minato, N.3
Irie, S.4
Takatsu, K.5
Kinashi, T.6
-
64
-
-
0036146452
-
Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses
-
Katagiri K, Hattori M, Minato N, Kinashi T. Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses. Mol Cell Biol 2002 22:1001 1015.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1001-1015
-
-
Katagiri, K.1
Hattori, M.2
Minato, N.3
Kinashi, T.4
-
65
-
-
0026031577
-
Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex
-
Beranger F, Goud B, Tavitian A, de Gunzburg J. Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex. Proc Natl Acad Sci USA 1991 88:1606 1610.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1606-1610
-
-
Beranger, F.1
Goud, B.2
Tavitian, A.3
De Gunzburg, J.4
-
66
-
-
0026744834
-
Association of rap1 and rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation
-
Maridonneau-Parini I, de Gunzburg J. Association of rap1 and rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation. J Biol Chem 1992 267:6396 6402.
-
(1992)
J Biol Chem
, vol.267
, pp. 6396-6402
-
-
Maridonneau-Parini, I.1
De Gunzburg, J.2
-
67
-
-
0027176155
-
Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils
-
Mollinedo F, Perez-Sala D, Gajate C, Jimenez B, Rodriguez P, Lacal JC. Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils. FEBS Lett 1993 326:209 214.
-
(1993)
FEBS Lett
, vol.326
, pp. 209-214
-
-
Mollinedo, F.1
Perez-Sala, D.2
Gajate, C.3
Jimenez, B.4
Rodriguez, P.5
Lacal, J.C.6
-
68
-
-
0028079846
-
Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes
-
Berger G, Quarck R, Tenza D, Levy-Toledano S, de Gunzburg J, Cramer EM. Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes. Br J Haematol 1994 88:372 382.
-
(1994)
Br J Haematol
, vol.88
, pp. 372-382
-
-
Berger, G.1
Quarck, R.2
Tenza, D.3
Levy-Toledano, S.4
De Gunzburg, J.5
Cramer, E.M.6
-
69
-
-
0028246501
-
Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex
-
Pizon V, Desjardins M, Bucci C, Parton RG, Zerial M. Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex. J Cell Sci 1994 107:1661 1670.
-
(1994)
J Cell Sci
, vol.107
, pp. 1661-1670
-
-
Pizon, V.1
Desjardins, M.2
Bucci, C.3
Parton, R.G.4
Zerial, M.5
-
70
-
-
0842266583
-
Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion
-
Bivona TG, Wiener HH, Ahearn IM, Silletti J, Chiu VK, Philips MR. Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. J Cell Biol 2004 164:461 470.
-
(2004)
J Cell Biol
, vol.164
, pp. 461-470
-
-
Bivona, T.G.1
Wiener, H.H.2
Ahearn, I.M.3
Silletti, J.4
Chiu, V.K.5
Philips, M.R.6
-
71
-
-
0037450766
-
Mechanism of the spatio-temporal regulation of Ras and Rap1
-
Ohba Y, Kurokawa K, Matsuda M. Mechanism of the spatio-temporal regulation of Ras and Rap1. EMBO J 2003 22:859 869.
-
(2003)
EMBO J
, vol.22
, pp. 859-869
-
-
Ohba, Y.1
Kurokawa, K.2
Matsuda, M.3
-
72
-
-
0035963331
-
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1
-
Mochizuki N, et al. Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature 2001 411:1065 1068.
-
(2001)
Nature
, vol.411
, pp. 1065-1068
-
-
Mochizuki, N.1
-
73
-
-
33845490019
-
The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking
-
Regelmann AG, Danzl NM, Wanjalla C, Alexandropoulos K. The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking. Immunity 2006 25:907 918.
-
(2006)
Immunity
, vol.25
, pp. 907-918
-
-
Regelmann, A.G.1
Danzl, N.M.2
Wanjalla, C.3
Alexandropoulos, K.4
-
74
-
-
30644470778
-
Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion
-
Duchniewicz M, Zemojtel T, Kolanczyk M, Grossmann S, Scheele JS, Zwartkruis FJ. Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion. Mol Cell Biol 2006 26:643 653.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 643-653
-
-
Duchniewicz, M.1
Zemojtel, T.2
Kolanczyk, M.3
Grossmann, S.4
Scheele, J.S.5
Zwartkruis, F.J.6
-
75
-
-
1642581670
-
LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds
-
Kinashi T, et al. LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds. Blood 2004 103:1033 1036.
-
(2004)
Blood
, vol.103
, pp. 1033-1036
-
-
Kinashi, T.1
-
76
-
-
0037827679
-
A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow
-
Alon R, et al. A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow. Blood 2003 101:4437 4445.
-
(2003)
Blood
, vol.101
, pp. 4437-4445
-
-
Alon, R.1
-
77
-
-
5044241734
-
RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion
-
Lafuente EM, et al. RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev Cell 2004 7:585 595.
-
(2004)
Dev Cell
, vol.7
, pp. 585-595
-
-
Lafuente, E.M.1
-
78
-
-
11844291360
-
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins
-
Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE. PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins. FEBS Lett 2005 579:455 463.
-
(2005)
FEBS Lett
, vol.579
, pp. 455-463
-
-
Jenzora, A.1
Behrendt, B.2
Small, J.V.3
Wehland, J.4
Stradal, T.E.5
-
79
-
-
34347337643
-
RIAM links the ADAP/SKAP-55 signaling module to Rap1 facilitating TCR-mediated integrin activation
-
Menasche G, Kliche S, Chen EJ, Stradal TE, Schraven B, Koretzky G. RIAM links the ADAP/SKAP-55 signaling module to Rap1 facilitating TCR-mediated integrin activation. Mol Cell Biol 2007 27:4070 4081.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4070-4081
-
-
Menasche, G.1
Kliche, S.2
Chen, E.J.3
Stradal, T.E.4
Schraven, B.5
Koretzky, G.6
-
80
-
-
0025332945
-
Mutations affecting embryonic cell migrations in Caenorhabditis elegans
-
Manser J, Wood WB. Mutations affecting embryonic cell migrations in Caenorhabditis elegans. Dev Genet 1990 11:49 64.
-
(1990)
Dev Genet
, vol.11
, pp. 49-64
-
-
Manser, J.1
Wood, W.B.2
-
81
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S, et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001 29:166 173.
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
-
82
-
-
5044244482
-
Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics
-
Krause M, et al. Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. Dev Cell 2004 7:571 583.
-
(2004)
Dev Cell
, vol.7
, pp. 571-583
-
-
Krause, M.1
-
84
-
-
33748454742
-
Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3
-
Han J, et al. Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3. Curr Biol 2006 16:1796 1806.
-
(2006)
Curr Biol
, vol.16
, pp. 1796-1806
-
-
Han, J.1
-
85
-
-
0141865705
-
Talin binding to integrin beta tails: A final common step in integrin activation
-
Tadokoro S, et al. Talin binding to integrin beta tails: a final common step in integrin activation. Science 2003 302:103 106.
-
(2003)
Science
, vol.302
, pp. 103-106
-
-
Tadokoro, S.1
-
86
-
-
0042490495
-
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
-
Katagiri K, Maeda A, Shimonaka M, Kinashi T. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol 2003 4:741 748.
-
(2003)
Nat Immunol
, vol.4
, pp. 741-748
-
-
Katagiri, K.1
Maeda, A.2
Shimonaka, M.3
Kinashi, T.4
-
87
-
-
5444267347
-
Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking
-
Katagiri K, et al. Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking. Nat Immunol 2004 5:1045 1051.
-
(2004)
Nat Immunol
, vol.5
, pp. 1045-1051
-
-
Katagiri, K.1
-
88
-
-
33747623042
-
Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
-
Katagiri K, Imamura M, Kinashi T. Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion. Nat Immunol 2006 7:919 928.
-
(2006)
Nat Immunol
, vol.7
, pp. 919-928
-
-
Katagiri, K.1
Imamura, M.2
Kinashi, T.3
-
89
-
-
0029558439
-
Cloning and characterization of a member of the MST subfamily of Ste20-like kinases
-
Creasy CL, Chernoff J. Cloning and characterization of a member of the MST subfamily of Ste20-like kinases. Gene 1995 167:303 306.
-
(1995)
Gene
, vol.167
, pp. 303-306
-
-
Creasy, C.L.1
Chernoff, J.2
-
90
-
-
0029790143
-
Newly identified stress-responsive protein kinases, Krs-1 and Krs-2
-
Taylor LK, Wang HC, Erikson RL. Newly identified stress-responsive protein kinases, Krs-1 and Krs-2. Proc Natl Acad Sci USA 1996 93:10099 10104.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10099-10104
-
-
Taylor, L.K.1
Wang, H.C.2
Erikson, R.L.3
-
91
-
-
0037524470
-
Protein kinase D: A family affair
-
Rykx A, et al. Protein kinase D: a family affair. FEBS Lett 2003 546:81 86.
-
(2003)
FEBS Lett
, vol.546
, pp. 81-86
-
-
Rykx, A.1
-
93
-
-
0034733650
-
Regulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesis
-
Vertommen D, et al. Regulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesis. J Biol Chem 2000 275:19567 19576.
-
(2000)
J Biol Chem
, vol.275
, pp. 19567-19576
-
-
Vertommen, D.1
-
94
-
-
23844509495
-
Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation
-
Medeiros RB, et al. Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation. Immunity 2005 23:213 226.
-
(2005)
Immunity
, vol.23
, pp. 213-226
-
-
Medeiros, R.B.1
-
95
-
-
34447337993
-
Compartmentalization of ITAM and integrin signaling by adapter molecules
-
Bezman N, Koretzky G. Compartmentalization of ITAM and integrin signaling by adapter molecules. Immunol Rev 2007 218:9 28.
-
(2007)
Immunol Rev
, vol.218
, pp. 9-28
-
-
Bezman, N.1
Koretzky, G.2
|