Telomere length variations in 6 mucosal cell types of gastric tissue observed using a novel quantitative fluorescence in situ hybridization method

Human Pathology

Volumn 38, Issue 8, 2007, Pages 1192-1200

  Aida, Junko ^a   Izumiyama Shimomura, Naotaka ^a   Nakamura, Ken ichi ^a   Ishii, Akio ^a   Ishikawa, Naoshi ^a   Honma, Naoko ^a   Kurabayashi, Rie ^a,b   Kammori, Makoto ^a,b   Poon, Steven S S ^c   Arai, Tomio ^a,d   Takubo, Kaiyo ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

^d Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

Centromere; h TERT; Stomach; Telomere; Tissue Q FISH

Indexed keywords

KI 67 ANTIGEN;

AGED; ARTICLE; CENTROMERE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MUCOSA CELL; NUCLEIC ACID PROBE; STOMACH CANCER; STOMACH MUCOSA; STOMACH TUMOR; TELOMERE;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; CELL PROLIFERATION; CENTROMERE; FEMALE; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION, FLUORESCENCE; KI-67 ANTIGEN; MALE; OLIGONUCLEOTIDE PROBES; PEPTIDE NUCLEIC ACIDS; STOMACH NEOPLASMS; TELOMERE;

EID: 34447306620     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.11.023     Document Type: Article

References (21)

1. Levy M.Z., Allsopp R.C., Futcher A.B., et al. Telomere end-replication problem and cell aging. J Mol Biol 225 (1992) 951-960
2. Takubo K., Izumiyama-Shimomura N., Honma N., et al. Telomere lengths are characteristic in each human individual. Exp Gerontol 37 (2002) 523-531
3. Nakamura K., Izumiyama-Shimomura N., Sawabe M., et al. Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol 119 (2002) 1014-1019
4. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 27 (2002) 339-344
5. Kountouras J., Zavos C., and Chatzopoulos D. New concepts of molecular biology on gastric carcinogenesis. Hepatogastroenterology 52 (2005) 1305-1312
6. Maruyama Y., Hanai H., Fujita M., et al. Telomere length and telomerase activity in carcinogenesis of the stomach. Jpn J Clin Oncol 27 (1997) 216-220
7. Furugori E., Hirayama R., Nakamura K., et al. Telomere shortening in gastric carcinoma with aging despite telomerase activation. J Cancer Res Clin Oncol 126 (2000) 481-485
8. Meeker A.K., Gage W.R., Hicks J.L., et al. Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining. Am J Pathol 160 (2002) 1259-1268
9. O'Sullivan J.N., Bronner M.P., Brentnall T.A., et al. Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat Genet 32 (2002) 280-284
10. O'Sullivan J.N., Finley J.C., Risques R., et al. Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms. Cytometry A 58 (2004) 120-131
11. Ferlicot S., Youssef N., Feneux D., et al. Measurement of telomere length on tissue sections using quantitative fluorescence in situ hybridization (Q-FISH). J Pathol 200 (2003) 661-666
12. Nakajima T., Moriguchi M., Katagishi T., et al. Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLD. Liver Int 26 (2006) 23-31
13. Kuniyasu H., Kitadai Y., Mieno H., et al. Helicobacter pylori infection is closely associated with telomere reduction in gastric mucosa. Oncology 65 (2003) 275-282
14. Perner S., Brüderlein S., Hasel C., et al. Quantifying telomere lengths of human individual chromosome arms by centromere-calibrated fluorescence in situ hybridization and digital imaging. Am J Pathol 163 (2003) 1751-1756
15. Owen D.A. Stomach. In: Sternberg S.S. (Ed). Histology for pathologists. 2nd ed. (1997), Lippincott-Raven Publishers, Philadelphia 483-491
16. Xia H.H.-X., and Talley N.J. Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis. Am J Gastroenterol 96 (2001) 16-26
17. Kameshima H., Yagihashi A., Yajima T., et al. Helicobacter pylori infection: augmentation of telomerase activity in cancer and noncancerous tissues. World J Surg 24 (2000) 1243-1249
18. Cakir C., Gulluoglu M.G., and Yilmazbayhan D. Cell proliferation rate and telomerase activity in the differential diagnosis between benign and malignant mesothelial proliferations. Pathology 38 (2006) 10-15
19. Chou S.J., Chen C.M., Harn H.J., et al. In situ detection of hTERT mRNA relates to Ki-67 labeling index in papillary thyroid carcinoma. J Surg Res 99 (2001) 75-83
20. Amioka T., Kitadai Y., Hiyama T., et al. Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions. Oncol Rep 11 (2004) 51-55
21. Xu L., Zhang S.-M., Wang Y.-P., et al. Relationship between DNA ploidy, expression of Ki-67 antigen and gastric cancer metastasis. World J Gastroenterol 5 (1999) 10-11