Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing

EMBO Journal

Volumn 26, Issue 13, 2007, Pages 3109-3123

  Unbehaun, Anett ^a   Marintchev, Assen ^c   Lomakin, Ivan B ^a   Didenko, Tatyana ^a   Wagner, Gerhard ^c   Hellen, Christopher U T ^a   Pestova, Tatyana V ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Directed hydroxyl radical cleavage; eIF5B; Ribosome; Translation; Translational GTPase

Indexed keywords

80 S RIBOSOME RIBONUCLEIC ACID; EUKARYOTIC INITIATION FACTOR 5B; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HYDROXYL RADICAL; INITIATION FACTOR; RIBOSOMAL PROTEIN S23; RIBOSOME PROTEIN; RIBOSOME RNA; RNA 18S; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; MODEL; MOLECULAR PROBE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; RIBOSOME SUBUNIT;

BASE SEQUENCE; CYSTEINE; EUKARYOTIC INITIATION FACTORS; HUMANS; HYDROXYL RADICAL; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RIBOSOMES; RNA, RIBOSOMAL;

EUKARYOTA;

EID: 34447302886     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601751     Document Type: Article

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