Phosphorylation of the protein phosphatase type 1 inhibitor protein CPI-17 by protein kinase C

Methods in Molecular Biology

Volumn 365, Issue , 2007, Pages 209-223

  Walsh, Michael P ^a   Susnjar, Marija ^a   Deng, Jingti ^a   Sutherland, Cindy ^a   Kiss, Eniko ^a   Wilson, David P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Ca 2+ sensitization; CPI 17; myosin light chain kinase; myosin light chain phosphatase; protein kinase C; smooth muscle contraction

Indexed keywords

CALCIUM; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN PHOSPHATASE; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C;

ANIMAL; ARTICLE; METABOLISM; PHOSPHORYLATION; SWINE;

ANIMALS; CALCIUM; MYOSIN-LIGHT-CHAIN KINASE; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; SWINE;

EID: 34447280389     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1385/1-59745-267-X:209     Document Type: Article

References (35)

1. Cohen, P. (2002) The origins of protein phosphorylation. Nature Cell Biol. 4, E127-E130. (Pubitemid 34521025)
2. Manning, G., Whyte, D. B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934. (Pubitemid 35425239)
3. Alonso, A., Sasin, J., Bottini, N., et al. (2004) Protein tyrosine phosphatases in the human genome. Cell 117, 699-711. (Pubitemid 38748887)
4. Honkanen, R. E. (2005) Serine/threonine protein phosphatase inhibitors with antitumor activity, in Handbook of Experimental Pharmacology: Inhibitors of Protein Kinases and Protein Phosphatases (Pinna, L. A., ed.), Springer-Verlag, Berlin, Vol. 167, pp. 295-317.
5. Allen, B. G. and Walsh, M. P. (1994) The biochemical basis of the regulation of smooth-muscle contraction. Trends Biochem. Sci. 19, 362-368. (Pubitemid 24281502)
6. Kamm, K. E. and Stull, J. T. (2001) Dedicated myosin light-chain kinases with diverse cellular functions. J. Biol. Chem. 276, 4527-4530.
7. Hartshorne, D. J., Ito, M., and Erdodi, F. (2004) Role of protein phosphatase type 1 in contractile functions: myosin phosphatase. J. Biol. Chem. 279, 37,211-37,214. (Pubitemid 39195423)
8. Oliver, C. J. and Shenolikar, S. (1998) Physiological importance of protein phosphatase inhibitors. Front. Biosci. 3, D961-D972.
9. Eto, M., Ohmori, T., Suzuki, M., Furuya, K., and Morita, F. (1995) A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. J. Biochem. (Tokyo) 118, 1104-1107. (Pubitemid 26013794)
10. Eto, M., Senba, S., Morita, F., and Yazawa, M. (1997) Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI-17) in smooth muscle: its specific localization in smooth muscle. FEBS Lett. 410, 356-360. (Pubitemid 27304096)
11. Woodsome, T. P., Eto, M., Everett, A., Brautigan, D. L., and Kitazawa, T. (2001) Expression of CPI-17 and myosin phosphatase correlates with Ca2+ sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J. Physiol. 535, 553-564. (Pubitemid 32825690)
12. Senba, S., Eto, M., and Yazawa, M. (1999) Identification of trimeric myosin phosphatase (PP1M) as a target for a novel PKC-potentiated protein phosphatase-1 inhibitory protein (CPI17) in porcine aorta smooth muscle. J. Biochem. (Tokyo) 125, 354-362. (Pubitemid 29112302)
13. Eto, M., Karginov, A., and Brautigan, D. L. (1999) A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes. Biochemistry 38, 16,952-16,957.
14. Liu, Q. R., Zhang, P. W., Zhen, Q., Walther, D., Wang, X. B., and Uhl, G. R. (2002) KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine. J. Biol. Chem. 277, 13,312-13,320. (Pubitemid 34952703)
15. Koyama, M., Ito, M., Feng, J., et al. (2000) Phosphorylation of CPI-17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho-kinase. FEBS Lett. 475, 197-200. (Pubitemid 30408452)
16. Hamaguchi, T., Ito, M., Feng, J., et al. (2000) Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. Biochem. Biophys. Res. Commun. 274, 825-830. (Pubitemid 30663704)
17. Deng, J. T., Sutherland, C., Brautigan, D. L., Eto, M., and Walsh, M. P. (2002) Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase. Biochem. J. 367, 517-524. (Pubitemid 35216828)
18. MacDonald, J. A., Eto, M., Borman, M. A., Brautigan, D. L., and Haystead, T. A. J. (2001) Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase. FEBS Lett. 493, 91-94. (Pubitemid 32245783)
19. Erdodi, F., Kiss, E., Walsh, M. P., et al. (2003) Phosphorylation of protein phosphatase type-1 inhibitory proteins by integrin-linked kinase and cyclic nucleotidedependent protein kinases. Biochem. Biophys. Res. Commun. 306, 382-387. (Pubitemid 36683084)
20. Takizawa, N., Koga, Y., and Ikebe, M. (2002) Phosphorylation of CPI17 and myosin binding subunit of type 1 protein phosphatase by p21-activated kinase. Biochem. Biophys. Res. Commun. 297, 773-778. (Pubitemid 35230317)
21. Kitazawa, T., Eto, M., Woodsome, T. P., and Brautigan, D. L. (2000) Agonists trigger G protein-mediated activation of the CPI-17 inhibitor phosphoprotein of myosin light-chain phosphatase to enhance vascular smooth muscle contractility. J. Biol. Chem. 275, 9897-9900. (Pubitemid 30202032)
22. Eto, M., Kitazawa, T., Yazawa, M., Mukai, H., Ono, Y., and Brautigan, D. L. (2001) Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C α and δ isoforms. J. Biol. Chem. 276, 29,072-29,078.
23. Niiro, N., Koga, Y., and Ikebe, M. (2003) Agonist-induced changes in the phosphorylation of the myosin-binding subunit of myosin light-chain phosphatase and CPI17, two regulatory factors of myosin light-chain phosphatase, in smooth muscle. Biochem. J. 369, 117-128. (Pubitemid 36174131)
24. Kitazawa, T., Eto, M., Woodsome, T. P., and Khalequzzamana, M. D. (2003) Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle. J. Physiol. 546, 879-889. (Pubitemid 36204521)
25. + sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855 but not Thr-697. Biochem. J. 389, 763-774. (Pubitemid 41121989)
26. Eto, M., Kitazawa, T., and Brautigan, D. L. (2004) Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits. Proc. Natl. Acad. Sci. USA 101, 8888-8893. (Pubitemid 38781581)
27. Li, L., Eto, M., Lee, M. R., Morita, F., Yazawa, M., and Kitazawa, T. (1998) Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle. J. Physiol. 508, 871-881. (Pubitemid 28220737)
28. Somlyo, A. P. and Somlyo, A. V. (2003) Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 83, 1325-1358. (Pubitemid 37222274)
29. Ohki, S., Eto, M., Kariya, E., et al. (2001) Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation. J. Mol. Biol. 314, 839-849. (Pubitemid 34087851)
30. Allen, B. G., Andrea, J. E., and Walsh, M. P. (1994) Identification and characterization of protein kinase Cζ-immunoreactive proteins. J. Biol. Chem. 269, 29,288-29,298. (Pubitemid 24366787)
31. +-binding protein and protein kinase C from bovine brain. Biochem. J. 224, 117-127. (Pubitemid 15188994)
32. Ngai, P. K., Carruthers, C. A., and Walsh, M. P. (1984) Isolation of the native form of chicken gizzard myosin light-chain kinase. Biochem. J. 218, 863-870. (Pubitemid 14165185)
33. Weber, L. P., Van Lierop, J. E., and Walsh, M. P. (1999) Ca2+-independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments. J. Physiol. 516, 805-824. (Pubitemid 29201904)
34. Andrea, J. E. and Walsh, M. P (1992) Protein kinase C of smooth muscle. Hypertension 20, 585-595.
35. Winder, S.J. and Walsh, M.P. (1990) Smooth muscle calponin. Inhibition of actomyosin MgATPase and regulation by phosphorylation. J. Biol. Chem. 265, 10,148-10,155.