Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 7, 2007, Pages 2396-2402

  Morrey, John D ^a   Siddharthan, Venkatraman ^a   Olsen, Aaron L ^a   Wang, Hong ^a   Julander, Justin G ^a   Hall, Jeffery O ^a   Li, Hua ^b   Nordstrom, Jeffrey L ^b   Koenig, Scott ^b   Johnson, Syd ^b   Diamond, Michael S ^c  

^a UTAH STATE UNIVERSITY   (United States)

^b Analytical Sciences   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HE16; NEUTRALIZING ANTIBODY; PALIVIZUMAB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN STEM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; FEMALE; INFECTION CONTROL; MORBIDITY; MORTALITY; NEUROLOGIC DISEASE; NONHUMAN; PONS; PRIORITY JOURNAL; RNA VIRUS INFECTION; SINGLE DRUG DOSE; SPINAL CORD; SYRIAN HAMSTER; TISSUE DISTRIBUTION; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; CRICETINAE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; MESOCRICETUS; PLAQUE ASSAY; RANDOM ALLOCATION; TIME FACTORS; TREATMENT OUTCOME; WEST NILE FEVER; WEST NILE VIRUS;

EID: 34447275442     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00147-07     Document Type: Article

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