Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat

Circulation Research

Volumn 93, Issue 3, 2003, Pages 230-237

  Kögler, Harald ^a   Hartmann, Oliver ^a   Leineweber, Kirsten ^b   Van Nguyen, Phuc ^a   Schott, Peter ^a   Brodde, Otto Erich ^b   Hasenfuss, Gerd ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Calcium; Contractility; Gene expression; Hypertrophy; Mechanical load

Indexed keywords

CALCIUM ION; MESSENGER RNA; MONOCROTALINE; MYOSIN; PHOSPHOLAMBAN; RYANODINE RECEPTOR; SODIUM CALCIUM EXCHANGE PROTEIN; TROPONIN T;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HEART CONTRACTION; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILE FORCE; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HEART VENTRICLE OVERLOAD; HEART WORK; MUSCLE ISOMETRIC CONTRACTION; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PULMONARY HYPERTENSION; RAT; SARCOLEMMA; SARCOPLASMIC RETICULUM;

ADRENERGIC BETA-AGONISTS; ANIMALS; BIOMECHANICS; BODY WEIGHT; CALCIUM; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION; HEART VENTRICLES; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; ISOPROTERENOL; MALE; MICROFILAMENTS; MONOCROTALINE; MYOCARDIAL CONTRACTION; NOREPINEPHRINE; ORGAN SIZE; RATS; RATS, WISTAR; RNA, MESSENGER; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; STRESS, MECHANICAL;

EID: 0042526001     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000085042.89656.C7     Document Type: Article

References (31)

1. Chien KR, Zhu H, Knowlton KU, Miller-Hance W, van Bilsen M, O'Brian TX, Evans SM. Transcriptional regulation during cardiac growth and development. Annu Rev Physiol. 1993;55:77-95.
2. 2+-ATPase in failing and nonfailing human myocardium. Circ Res. 1994;75:434-442.
3. 2+-ATPase in congestive heart failure due to myocardial infarction. Mol Cell Biochem. 1996;163/164:285-290.
4. Feldman AM, Weinberg EO, Ray PE, Lorell BH. Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res. 1993;73:184-192.
5. O'Rourke B, Kass DA, Tomaselli GF, Kääb S, Tunin R, Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies. Circ Res. 1999;84:562-570.
6. 2+ exchanger in end-stage human heart failure. Circ Res. 1994;75:443-453.
7. 2+ exchanger in failing human myocardium. Circulation. 1996;94:992-1002.
8. 2+ exchange in the infarcted heart: implications for excitation-contraction coupling. Circ Res. 1997;81:1083-1093.
9. Sipido KR, Volders PGA, de Groot SHM, Verdonck F, van de Werf F, Wellens HJJ, Vos MA. Enhanced Ca release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis. Circulation. 2000;102:2137-2144.
10. Kay JM, Harris P, Heath D. Pulmonary hypertension in rats produced by the ingestion of Crotalaria spectabilis seeds. Thorax. 1967;22:176-179.
11. Seyfarth T, Gerbershagen H-P, Giessler C, Leineweber K, Heinroth-Hoffmann I, Pönicke K, Brodde O-E. The cardiac β-adrenoceptor-G-protein(s)-adenylyl cyclase system in monocrotaline-treated rats. J Mol Cell Cardiol. 2000;32:2315-2326.
12. Leineweber K, Brandt K, Wludyka B, Beilfuß A, Pönicke K, Heinroth-Hoffmann I, Brodde O-E. Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac β-adrenoceptor system in experimental heart failure. Circ Res. 2002;91:1056-1062.
13. 2+ homeostasis in monocrotaline-induced right ventricular hypertrophy of the rat. Eur Heart J. 2002;23(suppl):329. Abstract.
14. Leineweber K, Seyfarth T, Brodde O-E. Chamber-specific alterations of noradrenaline uptake (uptake1) in right ventricles of monocrotaline-treated rats. Br J Pharmacol. 2000;131:1438-1444.
15. 2+ buffers. Methods Cell Biol. 1994;40:3-29.
16. Martell EA, Smith RM. Critical Stability Constants. Vol 3. New York, NY: Plenum Press; 1977.
17. Schäfers RF, Poller U, Pönicke K, Geissler M, Daul AE, Michel MC, Brodde O-E. Influence of adrenoceptor and muscarinic receptor blockade on the cardiovascular effects of exogenous noradrenaline and of endogenous noradrenaline released by infused tyramine. Naunyn Schmiedebergs Arch Pharmacol. 1997;355:239-249.
18. Lowry OH, Roseborough NJ, Farr AL, Randall RJ. Protein measurements with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
19. Malave HA, Taylor AA, Nattama J, Deswal A, Mann DL. Circulating levels of tumor necrosis factor correlate with indexes of depressed heart rate variability. Chest. 2003;123:716-724.
20. Brunner F, Wölkart G, Haleen S. Defective intracellular calcium handling in monocrotaline-induced right ventricular hypertrophy: protective effects of long-term endothelin-A receptor blockade with 2-benzo[1, 3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl-)-4-oxobut-2-enoate-sodium (PD 155080). J Pharmacol Exp Ther. 2002;300:442-449.
21. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell. 2000;101:365-376.
22. Baudet S, Kuznetsov A, Merciai N, Gorza L, Ventura-Clapier R. Biochemical, mechanical and energetic characterization of right ventricular hypertrophy in the ferret heart. J Mol Cell Cardiol. 1994;26:1573-1586.
23. Fan D, Wannenburg T, de Tombe PP. Decreased myocyte tension development and calcium responsiveness in rat right ventricular pressure overload. Circulation. 1997;95:2312-2317.
24. 2+-activated tension development in single adult cardiac myocytes. Circ Res. 1999;84:1310-1317.
25. Gibson LM, Wendt IR, Stephenson DG. Contractile activation properties of ventricular myocardium from hypothyroid, euthyroid and juvenile rats. Pflugers Arch. 1992;422:16-23.
26. Izumo S, Lompre AM, Matsuoka R, Koren G, Schwartz K, Nadal-Ginard B, Mahdavi V. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy: interaction between hemodynamic and thyroid hormone-induced signals. J Clin Invest. 1987;79:970-977.
27. Morano I, Adler K, Weismann K, Knorr A, Erdmann E, Böhm M. Correlation of myosin heavy chain expression in the rat with cAMP in different models of hypertension-induced cardiac hypertrophy. J Mol Cell Cardiol. 1993;25:387-394.
28. Brandt PW, Cox RN, Kawai M, Robinson T. Regulation of tension in skinned muscle fibers. J Mol Biol. 1982;79:997-1016.
29. Tardiff JC, Hewett TE, Factor SM, Vistrom KL, Robbins J, Leinwand LA. Expression of the β (slow) isoform of the MHC in the adult mouse heart causes dominant-negative functional effects. Am J Physiol. 2000;278:H412-H419.
30. Anderson PAW, Malouf NN, Oakeley AE, Pagani ED, Allen PD. Troponin T isoform expression in humans: a comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. Circ Res. 1991;69:1226-1233.
31. 2+ exchange. Circ Res. 2002;90:988-995.