3D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 15, 2007, Pages 4271-4274

  Yoo, Jakyung ^a   Thai, Khac Minh ^a   Kim, Dae Kee ^b   Lee, Ju Young ^c   Park, Hyun Ju ^a  

^a Sungkyunkwan University   (South Korea)

^b Ewha Womans University   (South Korea)

^c SK Chemicals   (South Korea)

Author keywords

3D QSAR modeling; PDE5 inhibitors; SK3530

Indexed keywords

PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL;

ARTICLE; DRUG BINDING; DRUG EFFICACY; DRUG INHIBITION; DRUG STRUCTURE; ERECTILE DYSFUNCTION; HUMAN; IN VITRO STUDY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; MODELS, MOLECULAR; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES;

EID: 34447121961     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.064     Document Type: Article

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