Requirement of reactive oxygen species generation in apoptosis of leukemia cells induced by 2-methoxyestradiol

Acta Pharmacologica Sinica

Volumn 28, Issue 7, 2007, Pages 1037-1044

  She, Miao Rong ^a,c   Li, Jing Gao ^b   Guo, Kun Yuan ^c   Lin, Wei ^a   Du, Xin ^a   Niu, Xin Qing ^c  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

2 methoxyestradiol; Apoptosis; Leukemia; Nitric oxide; Reactive oxygen species; Superoxides

Indexed keywords

2 METHOXYESTRADIOL; ACETYLCYSTEINE; DYE; HYDROETHIDINE; IODINE DERIVATIVE; LIPOCORTIN 5; MANUMYCIN; NITRIC OXIDE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TETRAZOLIUM;

APOPTOSIS; ARTICLE; CELL DAMAGE; CORRELATION FUNCTION; CYTOTOXICITY; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LEUKEMIA CELL; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; SENSOR;

APOPTOSIS; ESTRADIOL; HL-60 CELLS; HUMANS; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITRIC OXIDE; POLYENES; POLYUNSATURATED ALKAMIDES; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TUBULIN MODULATORS; U937 CELLS;

EID: 34347398891     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00604.x     Document Type: Article

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