Synthesis, physicochemical properties and in vitro permeation studies of new ketorolac ester derivatives

Current Drug Delivery

Volumn 4, Issue 3, 2007, Pages 205-210

  Puglia, Carmelo ^a   Filosa, Rosanna ^b   Peduto, Antonella ^b   De Caprariis, Paolo ^b   Boatto, Gianpiero ^c   Nieddu, Maria ^c   Santagati, Natale Alfredo ^a   Bonina, Francesco ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

In vitro; Ketorolac; Prodrug approach; Transdermal delivery

Indexed keywords

1 ALKYLAZACYCLOALKAN 2 ONE ESTER DERIVATIVE; 2 CHLOROETHANOL; 3 CHLOR 1 PROPANOL; 4 METHYLMORPHOLINE; CYCLOHEXANONE; CYCLOPENTANONE DERIVATIVE; KETOROLAC; MORPHOLINE; UNCLASSIFIED DRUG;

ANALGESIA; ARTICLE; DRUG ABSORPTION; DRUG PENETRATION; DRUG STABILITY; DRUG SYNTHESIS; ENZYME STABILITY; EVALUATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIPOPHILICITY; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ADMINISTRATION, CUTANEOUS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AZA COMPOUNDS; DRUG STABILITY; ESTERS; HUMANS; HYDROPHOBICITY; KETOROLAC; PERMEABILITY; PRODRUGS; SKIN; SKIN ABSORPTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34347382118     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720107781023893     Document Type: Article

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