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Volumn 76, Issue , 2007, Pages 263-280

Vitamin E Biotransformation in Humans

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT;

EID: 34347374255     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0083-6729(07)76009-0     Document Type: Review
Times cited : (42)

References (53)
  • 1
    • 0035816171 scopus 로고    scopus 로고
    • LLU-alpha, an endogenous metabolite of gamma-tocopherol, is more effective against metal nephrotoxicity in rats than gamma-tocopherol
    • Appenroth D., Karge E., Kiessling G., Wechter W.J., Winnefeld K., and Fleck C. LLU-alpha, an endogenous metabolite of gamma-tocopherol, is more effective against metal nephrotoxicity in rats than gamma-tocopherol. Toxicol. Lett. 122 (2001) 255-265
    • (2001) Toxicol. Lett. , vol.122 , pp. 255-265
    • Appenroth, D.1    Karge, E.2    Kiessling, G.3    Wechter, W.J.4    Winnefeld, K.5    Fleck, C.6
  • 2
    • 0036681851 scopus 로고    scopus 로고
    • In vitro antioxidant activity of 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman (alpha-CEHC), a vitamin E metabolite
    • Betancor-Fernandez A., Sies H., Stahl W., and Polidori M.C. In vitro antioxidant activity of 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman (alpha-CEHC), a vitamin E metabolite. Free Radic. Res. 36 (2002) 915-921
    • (2002) Free Radic. Res. , vol.36 , pp. 915-921
    • Betancor-Fernandez, A.1    Sies, H.2    Stahl, W.3    Polidori, M.C.4
  • 3
    • 33745865495 scopus 로고    scopus 로고
    • Antiproliferative effects of tocopherols (vitamin E) on murine glioma C6 cells: Homologue-specific control of PKC/ERK and cyclin signaling
    • Betti M., Minelli A., Canonico B., Castaldo P., Magi S., Aisa M.C., Piroddi M., Di Tomaso V., and Galli F. Antiproliferative effects of tocopherols (vitamin E) on murine glioma C6 cells: Homologue-specific control of PKC/ERK and cyclin signaling. Free Radic. Biol. Med. 41 (2006) 464-472
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 464-472
    • Betti, M.1    Minelli, A.2    Canonico, B.3    Castaldo, P.4    Magi, S.5    Aisa, M.C.6    Piroddi, M.7    Di Tomaso, V.8    Galli, F.9
  • 4
    • 0035879776 scopus 로고    scopus 로고
    • Tocopherols are metabolized in HepG2 cells by side chain ω-oxidation and consecutive β-oxidation
    • Birringer M., Drogan D., and Brigelius-Flohé R. Tocopherols are metabolized in HepG2 cells by side chain ω-oxidation and consecutive β-oxidation. Free Radic. Biol. Med. 31 (2001) 226-232
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 226-232
    • Birringer, M.1    Drogan, D.2    Brigelius-Flohé, R.3
  • 5
    • 0036791124 scopus 로고    scopus 로고
    • Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells
    • Birringer M., Pfluger P., Kluth D., Landes N., and Brigelius-Flohé R. Identities and differences in the metabolism of tocotrienols and tocopherols in HepG2 cells. J. Nutr. 132 (2002) 3113-3118
    • (2002) J. Nutr. , vol.132 , pp. 3113-3118
    • Birringer, M.1    Pfluger, P.2    Kluth, D.3    Landes, N.4    Brigelius-Flohé, R.5
  • 6
    • 0021323645 scopus 로고
    • Novel urinary metabolite of α-tocopherol in rats
    • Chiku S., Hamamura K., and Nakamura T. Novel urinary metabolite of α-tocopherol in rats. J. Lipid Res. 25 (1984) 40-48
    • (1984) J. Lipid Res. , vol.25 , pp. 40-48
    • Chiku, S.1    Hamamura, K.2    Nakamura, T.3
  • 7
    • 14944362640 scopus 로고    scopus 로고
    • Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells
    • Conte C., Floridi A., Aisa C., Piroddi M., Floridi A., and Galli F. Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. Ann. NY Acad. Sci. 1031 (2004) 391-394
    • (2004) Ann. NY Acad. Sci. , vol.1031 , pp. 391-394
    • Conte, C.1    Floridi, A.2    Aisa, C.3    Piroddi, M.4    Floridi, A.5    Galli, F.6
  • 8
    • 0026066882 scopus 로고
    • Absorption, transport and metabolism of vitamin E
    • Drevon C.A. Absorption, transport and metabolism of vitamin E. Free Radic. Res. Commun. 4 (1991) 229-246
    • (1991) Free Radic. Res. Commun. , vol.4 , pp. 229-246
    • Drevon, C.A.1
  • 9
    • 20144378760 scopus 로고    scopus 로고
    • Beyond vitamin E supplementation: An alternative strategy to improve vitamin E status
    • Frank J. Beyond vitamin E supplementation: An alternative strategy to improve vitamin E status. J. Plant Physiol. 162 (2005) 834-843
    • (2005) J. Plant Physiol. , vol.162 , pp. 834-843
    • Frank, J.1
  • 10
    • 0037082352 scopus 로고    scopus 로고
    • Gas chromatography mass spectrometry analysis of carboxyethyl-hydroxychroman metabolites of alpha- and gamma-tocopherol in human plasma
    • Galli F., Lee R., Dunster C., and Kelly F.J. Gas chromatography mass spectrometry analysis of carboxyethyl-hydroxychroman metabolites of alpha- and gamma-tocopherol in human plasma. Free Radic. Biol. Med. 32 (2002) 333-340
    • (2002) Free Radic. Biol. Med. , vol.32 , pp. 333-340
    • Galli, F.1    Lee, R.2    Dunster, C.3    Kelly, F.J.4
  • 12
    • 1642527428 scopus 로고    scopus 로고
    • Accumulation of vitamin E metabolites in the blood of renal failure patients
    • Galli F., Floridi A.G., Floridi A., and Buoncristiani U. Accumulation of vitamin E metabolites in the blood of renal failure patients. Clin. Nutr. 23 (2004) 205-212
    • (2004) Clin. Nutr. , vol.23 , pp. 205-212
    • Galli, F.1    Floridi, A.G.2    Floridi, A.3    Buoncristiani, U.4
  • 13
    • 1042267393 scopus 로고    scopus 로고
    • The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation
    • Galli F., Stabile A.M., Betti M., Conte C., Pistilli A., Rende M., Floridi A., and Azzi A. The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation. Arch. Biochem. Biophys. 423 (2004) 97-102
    • (2004) Arch. Biochem. Biophys. , vol.423 , pp. 97-102
    • Galli, F.1    Stabile, A.M.2    Betti, M.3    Conte, C.4    Pistilli, A.5    Rende, M.6    Floridi, A.7    Azzi, A.8
  • 14
    • 10044261980 scopus 로고    scopus 로고
    • A comparison between the antioxidant and peroxynitrite-scavenging functions of the vitamin E metabolites alpha- and gamma-carboxyethyl-6-hydroxychromans
    • Galli F., Piroddi M., Lannone A., Pagliarani S., Tomasi A., and Floridi A. A comparison between the antioxidant and peroxynitrite-scavenging functions of the vitamin E metabolites alpha- and gamma-carboxyethyl-6-hydroxychromans. Int. J. Vitam. Nutr. Res. 74 (2004) 362-373
    • (2004) Int. J. Vitam. Nutr. Res. , vol.74 , pp. 362-373
    • Galli, F.1    Piroddi, M.2    Lannone, A.3    Pagliarani, S.4    Tomasi, A.5    Floridi, A.6
  • 15
    • 0346648799 scopus 로고    scopus 로고
    • The uptake of tocopherols by RAW 264.7 macrophages
    • Gao R., Stone W.L., Huang T., Papas A.M., and Qui M. The uptake of tocopherols by RAW 264.7 macrophages. Nutr. J. 1 (2002) 2-8
    • (2002) Nutr. J. , vol.1 , pp. 2-8
    • Gao, R.1    Stone, W.L.2    Huang, T.3    Papas, A.M.4    Qui, M.5
  • 17
    • 0034214168 scopus 로고    scopus 로고
    • Occurrence and determination of a natriuretic hormone, 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman, in rat plasma, urine, and bile
    • Hattori A., Fukushima T., and Imai K. Occurrence and determination of a natriuretic hormone, 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman, in rat plasma, urine, and bile. Anal. Biochem. 281 (2000) 209-215
    • (2000) Anal. Biochem. , vol.281 , pp. 209-215
    • Hattori, A.1    Fukushima, T.2    Imai, K.3
  • 18
    • 0033662499 scopus 로고    scopus 로고
    • Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats
    • Hattori A., Fukushima T., Yoshimura H., Abe K., and Imai K. Production of LLU-alpha following an oral administration of gamma-tocotrienol or gamma-tocopherol to rats. Biol. Pharm. Bull. 23 (2000) 1395-1397
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 1395-1397
    • Hattori, A.1    Fukushima, T.2    Yoshimura, H.3    Abe, K.4    Imai, K.5
  • 19
    • 0035185941 scopus 로고    scopus 로고
    • Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention
    • Jiang Q., Christen S., Shigenaga M.K., and Ames B.N. Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am. J. Clin. Nutr. 74 (2001) 714-722
    • (2001) Am. J. Clin. Nutr. , vol.74 , pp. 714-722
    • Jiang, Q.1    Christen, S.2    Shigenaga, M.K.3    Ames, B.N.4
  • 20
    • 0034074439 scopus 로고    scopus 로고
    • Studies of the metabolism of alpha-tocopherol stereoisomers in rats using [5-methyl-(14)C]SRR- and RRR-alpha-tocopherol
    • Kaneko K., Kiyose C., Ueda T., Ichikawa H., and Igarashi O. Studies of the metabolism of alpha-tocopherol stereoisomers in rats using [5-methyl-(14)C]SRR- and RRR-alpha-tocopherol. J. Lipid Res. 41 (2000) 357-367
    • (2000) J. Lipid Res. , vol.41 , pp. 357-367
    • Kaneko, K.1    Kiyose, C.2    Ueda, T.3    Ichikawa, H.4    Igarashi, O.5
  • 21
    • 14944366502 scopus 로고    scopus 로고
    • Inter- and intra-individual vitamin E uptake in healthy subjects is highly repeatable across a wide supplementation dose range
    • Kelly F.J., Lee R., and Mudway I.S. Inter- and intra-individual vitamin E uptake in healthy subjects is highly repeatable across a wide supplementation dose range. Ann. NY Acad. Sci. 1031 (2004) 22-39
    • (2004) Ann. NY Acad. Sci. , vol.1031 , pp. 22-39
    • Kelly, F.J.1    Lee, R.2    Mudway, I.S.3
  • 22
    • 4243915535 scopus 로고    scopus 로고
    • Quantification of urinary metabolites of α-tocopherol and γ-tocopherol in normal European subjects
    • Lee R., and Kelly F.J. Quantification of urinary metabolites of α-tocopherol and γ-tocopherol in normal European subjects. Free Radic. Biol. Med. 27 Suppl. 1 (1999) S38-S39
    • (1999) Free Radic. Biol. Med. , vol.27 , Issue.SUPPL. 1
    • Lee, R.1    Kelly, F.J.2
  • 23
    • 27244433672 scopus 로고    scopus 로고
    • Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration
    • Leonard S.W., Gumpricht E., Devereaux M.W., Sokol R.J., and Traber M. Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration. J. Lipid Res. 46 (2005) 1068-1075
    • (2005) J. Lipid Res. , vol.46 , pp. 1068-1075
    • Leonard, S.W.1    Gumpricht, E.2    Devereaux, M.W.3    Sokol, R.J.4    Traber, M.5
  • 24
    • 14644404970 scopus 로고    scopus 로고
    • Studies in humans using deuterium-labeled α- and γ-tocopherols demonstrate faster plasma γ-tocopherol disappearance and greater γ-metabolite production
    • Leonard S.W., Paterson E., Atkinson J.K., Ramakrishnan R., Cross C.E., and Traber M.G. Studies in humans using deuterium-labeled α- and γ-tocopherols demonstrate faster plasma γ-tocopherol disappearance and greater γ-metabolite production. Free Radic. Biol. Med. 38 (2005) 857-866
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 857-866
    • Leonard, S.W.1    Paterson, E.2    Atkinson, J.K.3    Ramakrishnan, R.4    Cross, C.E.5    Traber, M.G.6
  • 25
    • 0035113436 scopus 로고    scopus 로고
    • α- and γ-Tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine
    • Lodge J.K., Ridlington J., Leonard S., Vaule H., and Traber M.G. α- and γ-Tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine. Lipids 36 (2001) 43-48
    • (2001) Lipids , vol.36 , pp. 43-48
    • Lodge, J.K.1    Ridlington, J.2    Leonard, S.3    Vaule, H.4    Traber, M.G.5
  • 26
    • 2342487823 scopus 로고    scopus 로고
    • Cellular mechanisms of vitamin E uptake: Relevance in alpha-tocopherol metabolism and potential implications for disease
    • Mardones P., and Rigotti A. Cellular mechanisms of vitamin E uptake: Relevance in alpha-tocopherol metabolism and potential implications for disease. J. Nutr. Biochem. 15 (2004) 252-260
    • (2004) J. Nutr. Biochem. , vol.15 , pp. 252-260
    • Mardones, P.1    Rigotti, A.2
  • 28
    • 33747102069 scopus 로고    scopus 로고
    • Absence of VLDL secretion does not affect α-tocopherol content in peripheral tissues
    • Minehira-Castelli K., Leonard S.W., Walker Q.M., Traber M.G., and Young S.G. Absence of VLDL secretion does not affect α-tocopherol content in peripheral tissues. J. Lipid Res. 47 (2006) 1733-1738
    • (2006) J. Lipid Res. , vol.47 , pp. 1733-1738
    • Minehira-Castelli, K.1    Leonard, S.W.2    Walker, Q.M.3    Traber, M.G.4    Young, S.G.5
  • 29
    • 0037352264 scopus 로고    scopus 로고
    • Measurement of vitamin E metabolites by high-performance liquid chromatography during high-dose administration of alpha-tocopherol
    • Morinobu T., Yoshikawa S., Hamamura K., and Tamai H. Measurement of vitamin E metabolites by high-performance liquid chromatography during high-dose administration of alpha-tocopherol. Eur. J. Clin. Nutr. 57 (2003) 410-414
    • (2003) Eur. J. Clin. Nutr. , vol.57 , pp. 410-414
    • Morinobu, T.1    Yoshikawa, S.2    Hamamura, K.3    Tamai, H.4
  • 31
    • 0034673567 scopus 로고    scopus 로고
    • A novel 5′-carboxychroman metabolite of gamma-tocopherol secreted by HepG2 cells and excreted in human urine
    • Parker R.S., and Swanson J.E. A novel 5′-carboxychroman metabolite of gamma-tocopherol secreted by HepG2 cells and excreted in human urine. Biochem. Biophys. Res. Commun. 269 (2000) 580-583
    • (2000) Biochem. Biophys. Res. Commun. , vol.269 , pp. 580-583
    • Parker, R.S.1    Swanson, J.E.2
  • 33
  • 34
    • 25444455119 scopus 로고    scopus 로고
    • Intracellular trafficking of vitamin E in hepatocytes: The role of tocopherol transfer protein
    • Qian J., Morley S., Wilson K., Nava P., Atkinson J., and Manor D. Intracellular trafficking of vitamin E in hepatocytes: The role of tocopherol transfer protein. J. Lipid Res. 46 (2005) 2072-2082
    • (2005) J. Lipid Res. , vol.46 , pp. 2072-2082
    • Qian, J.1    Morley, S.2    Wilson, K.3    Nava, P.4    Atkinson, J.5    Manor, D.6
  • 35
    • 0036933122 scopus 로고    scopus 로고
    • Tocopherol metabolites 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and 2,7,8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman (gamma-CEHC) in human serum after a single dose of natural vitamin E
    • Radosavac D., Graf P., Polidori M.C., Sies H., and Stahl W. Tocopherol metabolites 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and 2,7,8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman (gamma-CEHC) in human serum after a single dose of natural vitamin E. Eur. J. Nutr. 41 (2002) 119-124
    • (2002) Eur. J. Nutr. , vol.41 , pp. 119-124
    • Radosavac, D.1    Graf, P.2    Polidori, M.C.3    Sies, H.4    Stahl, W.5
  • 37
    • 0028858639 scopus 로고
    • Novel urinary metabolite of alpha-tocopherol, 2,5,7,8-tetramethyl-2(2′-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply?
    • Schultz M., Leist M., Petrzika M., Gassmann B., and Brigelius-Flohé R. Novel urinary metabolite of alpha-tocopherol, 2,5,7,8-tetramethyl-2(2′-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply?. Am. J. Clin. Nutr. 62 Suppl. 6 (1995) 1527S-1534S
    • (1995) Am. J. Clin. Nutr. , vol.62 , Issue.SUPPL. 6
    • Schultz, M.1    Leist, M.2    Petrzika, M.3    Gassmann, B.4    Brigelius-Flohé, R.5
  • 38
    • 77049283494 scopus 로고
    • The metabolism of vitamin E. II. Purification and characterization of urinary metabolites of alpha-tocopherol
    • Simon E.J., Eisengart A., Sundneim L., and Milorat A.T. The metabolism of vitamin E. II. Purification and characterization of urinary metabolites of alpha-tocopherol. J. Biol. Chem. 221 (1956) 807-817
    • (1956) J. Biol. Chem. , vol.221 , pp. 807-817
    • Simon, E.J.1    Eisengart, A.2    Sundneim, L.3    Milorat, A.T.4
  • 39
    • 0141481799 scopus 로고    scopus 로고
    • Vitamin E supplementation increases circulating vitamin E metabolites tenfold in end-stage renal disease patients
    • Smith K.S., Lee C.L., Ridlington J.W., Leonard S.W., Devaraj S., and Traber M.G. Vitamin E supplementation increases circulating vitamin E metabolites tenfold in end-stage renal disease patients. Lipids 38 (2003) 813-819
    • (2003) Lipids , vol.38 , pp. 813-819
    • Smith, K.S.1    Lee, C.L.2    Ridlington, J.W.3    Leonard, S.W.4    Devaraj, S.5    Traber, M.G.6
  • 40
    • 0037067711 scopus 로고    scopus 로고
    • Cytochrome P450 ω-hydroxylase pathway of tocopherol catabolism
    • Sontag T.J., and Parker R.S. Cytochrome P450 ω-hydroxylase pathway of tocopherol catabolism. J. Biol. Chem. 277 (2002) 25290-25296
    • (2002) J. Biol. Chem. , vol.277 , pp. 25290-25296
    • Sontag, T.J.1    Parker, R.S.2
  • 41
    • 0033571604 scopus 로고    scopus 로고
    • Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman and 2,7,8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman in human serum
    • Stahl W., Graf P., Brigelius-Flohé R., Wechter W., and Sies H. Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman and 2,7,8-trimethyl-2-(2′-carboxyethyl)-6-hydroxychroman in human serum. Anal. Biochem. 275 (1999) 254-259
    • (1999) Anal. Biochem. , vol.275 , pp. 254-259
    • Stahl, W.1    Graf, P.2    Brigelius-Flohé, R.3    Wechter, W.4    Sies, H.5
  • 43
    • 0032933234 scopus 로고    scopus 로고
    • Urinary excretion of 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman is a major route of elimination of gamma-tocopherol in humans
    • Swanson J.E., Ben R.N., Burton G.W., and Parker R.S. Urinary excretion of 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman is a major route of elimination of gamma-tocopherol in humans. J. Lipid Res. 40 (1999) 665-671
    • (1999) J. Lipid Res. , vol.40 , pp. 665-671
    • Swanson, J.E.1    Ben, R.N.2    Burton, G.W.3    Parker, R.S.4
  • 44
    • 1042290478 scopus 로고    scopus 로고
    • Vitamin E, nuclear receptors and xenobiotic metabolism
    • Traber M.G. Vitamin E, nuclear receptors and xenobiotic metabolism. Arch. Biochem. Biophys. 423 (2004) 6-11
    • (2004) Arch. Biochem. Biophys. , vol.423 , pp. 6-11
    • Traber, M.G.1
  • 45
    • 0032778334 scopus 로고    scopus 로고
    • Molecular mechanisms of vitamin E transport
    • Traber M.G., and Arai H. Molecular mechanisms of vitamin E transport. Annu. Rev. Nutr. 19 (1999) 343-355
    • (1999) Annu. Rev. Nutr. , vol.19 , pp. 343-355
    • Traber, M.G.1    Arai, H.2
  • 46
    • 0032538402 scopus 로고    scopus 로고
    • Synthetic as compared with natural vitamin E is preferentially excreted as alpha-CEHC in human urine: Studies using deuterated alpha-tocopheryl acetates
    • Traber M.G., Elsner A., and Brigelius-Flohe R. Synthetic as compared with natural vitamin E is preferentially excreted as alpha-CEHC in human urine: Studies using deuterated alpha-tocopheryl acetates. FEBS Lett. 437 (1998) 145-148
    • (1998) FEBS Lett. , vol.437 , pp. 145-148
    • Traber, M.G.1    Elsner, A.2    Brigelius-Flohe, R.3
  • 48
    • 13844255025 scopus 로고    scopus 로고
    • Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets
    • Traber M.G., Siddens L.K., Leonard S.W., Schock B., Gohil K., Krueger S.K., Cross C.E., and Williams D.E. Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets. Free Radic. Biol. Med. 38 (2005) 773-785
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 773-785
    • Traber, M.G.1    Siddens, L.K.2    Leonard, S.W.3    Schock, B.4    Gohil, K.5    Krueger, S.K.6    Cross, C.E.7    Williams, D.E.8
  • 49
    • 0026570589 scopus 로고
    • Comparative uptake of alpha- and gamma-tocopherol by human endothelial cells
    • Tran K., and Chan A.C. Comparative uptake of alpha- and gamma-tocopherol by human endothelial cells. Lipids 27 (1992) 38-41
    • (1992) Lipids , vol.27 , pp. 38-41
    • Tran, K.1    Chan, A.C.2
  • 51
    • 0035140716 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status
    • Yap S.P., Yuen K.H., and Wong J.W. Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status. J. Pharm. Pharmacol. 53 (2001) 67-71
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 67-71
    • Yap, S.P.1    Yuen, K.H.2    Wong, J.W.3
  • 52
    • 0141957270 scopus 로고    scopus 로고
    • Antioxidant effects of alpha- and gamma-carboxyethyl-6-hydroxychromans
    • Yoshida Y., and Niki E. Antioxidant effects of alpha- and gamma-carboxyethyl-6-hydroxychromans. Biofactors 16 (2002) 93-103
    • (2002) Biofactors , vol.16 , pp. 93-103
    • Yoshida, Y.1    Niki, E.2
  • 53
    • 13244291335 scopus 로고    scopus 로고
    • Long-chain carboxychromanols are the major metabolites of tocopherols and tocotrienols in A549 lung epithelial cells but not HepG2 cells
    • You C.S., Sontag T.J., Swanson J.E., and Parker R.S. Long-chain carboxychromanols are the major metabolites of tocopherols and tocotrienols in A549 lung epithelial cells but not HepG2 cells. J. Nutr. 135 (2005) 227-232
    • (2005) J. Nutr. , vol.135 , pp. 227-232
    • You, C.S.1    Sontag, T.J.2    Swanson, J.E.3    Parker, R.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.