α-Tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats

Free Radical Biology and Medicine

Volumn 41, Issue 7, 2006, Pages 1069-1078

  Mustacich, Debbie J ^a   Leonard, Scott W ^a   Devereaux, Michael W ^b   Sokol, Ronald J ^b   Traber, Maret G ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b CHILDREN S HOSPITAL   (United States)

Author keywords

Tocopherol; CYP; Cytochrome P450; MDR1; p Glycoprotein; Rat; Xenobiotic metabolism

Indexed keywords

ABC TRANSPORTER; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL TRANSFER PROTEIN; CARRIER PROTEIN; CYTOCHROME P450; CYTOCHROME P450 2B; CYTOCHROME P450 3A; CYTOCHROME P450 4F; DRUG METABOLITE; DRUG METABOLIZING ENZYME; GLYCOPROTEIN P; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG EXCRETION; DRUG LIVER LEVEL; DRUG STRUCTURE; ENZYME REGULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; XENOBIOTIC METABOLISM;

ALPHA-TOCOPHEROL; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHROMANS; CYTOCHROME P-450 ENZYME SYSTEM; INJECTIONS, SUBCUTANEOUS; LIVER; LIVER EXTRACTS; MALE; MODELS, MOLECULAR; PROPIONATES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 33748446961     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.06.022     Document Type: Article

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