Identification of Human MVB12 Proteins as ESCRT-I Subunits that Function in HIV Budding

Cell Host and Microbe

Volumn 2, Issue 1, 2007, Pages 41-53

  Morita, Eiji ^a   Sandrin, Virginie ^a   Alam, Steven L ^a   Eckert, Debra M ^a   Gygi, Steven P ^b   Sundquist, Wesley I ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CELLBIO; MICROBIO

Indexed keywords

ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT 1 PROTEIN; GAG PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN ESCRT 1; PROTEIN MVB12A; PROTEIN MVB12B; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL BUDDING; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDRODYNAMICS; METAZOON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONTENT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; VIRION; VIRUS CELL INTERACTION; VIRUS MORPHOLOGY; VIRUS VIRULENCE;

BIOLOGICAL TRANSPORT; ENDOSOMES; HIV-1; HUMANS; MORPHOGENESIS; PROTEIN SUBUNITS; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1; METAZOA;

EID: 34347339528     PISSN: 19313128     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chom.2007.06.003     Document Type: Article

References (37)

1. Babst M., Odorizzi G., Estepa E.J., and Emr S.D. Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1 (2000) 248-258
2. Babst M., Sato T.K., Banta L.M., and Emr S.D. Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO J. 16 (1997) 1820-1831
3. Babst M., Wendland B., Estepa E.J., and Emr S.D. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17 (1998) 2982-2993
4. Bache K.G., Brech A., Mehlum A., and Stenmark H. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J. Cell Biol. 162 (2003) 435-442
5. Bache K.G., Slagsvold T., Cabezas A., Rosendal K.R., Raiborg C., and Stenmark H. The Growth-Regulatory Protein HCRP1/hVps37A is a Subunit of Mammalian ESCRT-I and Mediates Receptor Downregulation. Mol. Biol.Cell. 15 (2004) 4337-4346
6. Bieniasz P.D. Late budding domains and host proteins in enveloped virus release. Virology 344 (2006) 55-63
7. Chu T., Sun J., Saksena S., and Emr S.D. New component of ESCRT-I regulates endosomal sorting complex assembly. J. Cell Biol. 175 (2006) 815-823
8. Cole J.L. Analysis of heterogeneous interactions. Methods Enzymol. 384 (2004) 212-232
9. Curtiss M., Jones C., and Babst M. Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol. Biol. Cell 18 (2007) 636-645
10. Demirov D.G., and Freed E.O. Retrovirus budding. Virus Res. 106 (2004) 87-102
11. Durocher Y., Perret S., and Kamen A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res. 30 (2002) E9
12. Eastman S.W., Martin-Serrano J., Chung W., Zang T., and Bieniasz P.D. Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. J. Biol. Chem. 280 (2005) 628-636
13. Garrus J.E., von Schwedler U.K., Pornillos O.W., Morham S.G., Zavitz K.H., Wang H.E., Wettstein D.A., Stray K.M., Cote M., Rich R.L., et al. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107 (2001) 55-65
14. Gill D.J., Teo H., Sun J., Perisic O., Veprintsev D.B., Emr S.D., and Williams R.L. Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. EMBO J. 26 (2007) 600-612
15. Gill D.J., Teo H., Sun J., Perisic O., Veprintsev D.B., Vallis Y., Emr S.D., and Williams R.L. Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies. Biochem. Soc. Symp. 74 (2007) 47-57
16. Gruenberg J., and Stenmark H. The biogenesis of multivesicular endosomes. Nat. Rev. Mol. Cell Biol. 5 (2004) 317-323
17. Hurley J.H., and Emr S.D. The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu. Rev. Biophys. Biomol. Struct. 35 (2006) 277-298
18. Katzmann D.J., Babst M., and Emr S.D. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106 (2001) 145-155
19. Katzmann D.J., Stefan C.J., Babst M., and Emr S.D. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J. Cell Biol. 162 (2003) 413-423
20. Kostelansky M.S., Schluter C., Tam Y.Y., Lee S., Ghirlando R., Beach B., Conibear E., and Hurley J.H. Molecular Architecture and Functional Model of the Complete Yeast ESCRT-I Heterotetramer. Cell 129 (2007) 485-498
21. Kostelansky M.S., Sun J., Lee S., Kim J., Ghirlando R., Hierro A., Emr S.D., and Hurley J.H. Structural and functional organization of the ESCRT-I trafficking complex. Cell 125 (2006) 113-126
22. Lu Q., Hope L.W., Brasch M., Reinhard C., and Cohen S.N. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc. Natl. Acad. Sci. USA 100 (2003) 7626-7631
23. Martin-Serrano J., Zang T., and Bieniasz P.D. HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress. Nat. Med. 7 (2001) 1313-1319
24. Martin-Serrano J., Zang T., and Bieniasz P.D. Role of ESCRT-I in Retroviral Budding. J. Virol. 77 (2003) 4794-4804
25. Morita E., and Sundquist W.I. Retrovirus budding. Annu. Rev. Cell Dev. Biol. 20 (2004) 395-425
26. Oestreich A.J., Davies B.A., Payne J.A., and Katzmann D.J. Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway. Mol. Biol. Cell 18 (2007) 646-657
27. Pornillos O., Alam S.L., Davis D.R., and Sundquist W.I. Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nat. Struct. Biol. 9 (2002) 812-817
28. Pornillos O., Higginson D.S., Stray K.M., Fisher R.D., Garrus J.E., Payne M., He G.P., Wang H.E., Morham S.G., and Sundquist W.I. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J. Cell Biol. 162 (2003) 425-434
29. Shehu-Xhilaga M., Ablan S., Demirov D.G., Chen C., Montelaro R.C., and Freed E.O. Late domain-dependent inhibition of equine infectious anemia virus budding. J. Virol. 78 (2004) 724-732
30. Stuchell M.D., Garrus J.E., Muller B., Stray K.M., Ghaffarian S., McKinnon R., Krausslich H.G., Morham S.G., and Sundquist W.I. The Human Endosomal Sorting Complex Required for Transport (ESCRT-I) and Its Role in HIV-1 Budding. J. Biol. Chem. 279 (2004) 36059-36071
31. Sundquist W.I., Schubert H.L., Kelly B.N., Hill G.C., Holton J.M., and Hill C.P. Ubiquitin recognition by the human TSG101 protein. Mol. Cell 13 (2004) 783-789
32. Swingler S., Gallay P., Camaur D., Song J., Abo A., and Trono D. The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix. J. Virol. 71 (1997) 4372-4377
33. Teo H., Gill D.J., Sun J., Perisic O., Veprintsev D.B., Vallis Y., Emr S.D., and Williams R.L. ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell 125 (2006) 99-111
34. Teo H., Veprintsev D.B., and Williams R.L. Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins. J. Biol. Chem. 279 (2004) 28689-28696
35. von Schwedler U.K., Stemmler T.L., Klishko V.Y., Li S., Albertine K.H., Davis D.R., and Sundquist W.I. Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly. EMBO J. 17 (1998) 1555-1568
36. von Schwedler U.K., Stuchell M., Muller B., Ward D.M., Chung H.Y., Morita E., Wang H.E., Davis T., He G.P., Cimbora D.M., et al. The protein network of HIV budding. Cell 114 (2003) 701-713
37. Welsch S., Habermann A., Jager S., Muller B., Krijnse-Locker J., and Krausslich H.G. Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function. Traffic 7 (2006) 1551-1566