Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

EMBO Journal

Volumn 26, Issue 2, 2007, Pages 600-612

  Gill, David J ^a   Teo, Hsiangling ^a   Sun, Ji ^b   Perisic, Olga ^a   Veprintsev, Dmitry B ^c   Emr, Scott D ^b   Williams, Roger L ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

CHMP; ESCRT; HIV budding; MVB; NZF finger

Indexed keywords

ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT 1 PROTEIN; ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT 2 PROTEIN; FUNGAL PROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROPHOBICITY; IN VITRO STUDY; MEMBRANE VESICLE; MOLECULAR MECHANICS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; ENDOSOMES; FUNGAL PROTEINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VESICULAR TRANSPORT PROTEINS; XENOPUS LAEVIS; YEASTS;

EID: 33846517041     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601501     Document Type: Article

References (35)

1. Adams SR, Campbell RE, Gross LA, Martin BR, Walkup GK, Yao Y, Llopis J, Tsien RY (2002) New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications. J Am Chem Soc 124: 6063-6076
2. Alam SL, Sun J, Payne M, Welch BD, Blake BK, Davis DR, Meyer HH, Emr SD, Sundquist WI (2004) Ubiquitin interactions of NZF zinc fingers. EMBO J 23: 1411-1421
3. Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD (2002a) ESCRT-III: an endosome-associated heterooligomeric protein complex required for MVB sorting. Dev Cell 3: 271-282
4. Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD (2002b) Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev Cell 3: 283-289
5. Bache KG, Stuffers S, Malerod L, Slagsvold T, Raiborg C, Lechardeur D, Walchli S, Lukacs GL, Brech A, Stenmark H (2006) The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. Mol Biol Cell 17: 2513-2523
6. Bilodeau PS, Winistorfer SC, Kearney WR, Robertson AD, Piper RC (2003) Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome. J Cell Biol 163: 237-243
7. Bonangelino CJ, Chavez EM, Bonifacino JS (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13: 2486-2501
8. Bowers K, Lottridge J, Helliwell SB, Goldthwaite LM, Luzio JP, Stevens TH (2004) Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae. Traffic 5: 194-210
9. Chu T, Sun J, Saksena S, Emr SD (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175: 815-823
10. Doyotte A, Russell MR, Hopkins CR,Woodman PG (2005) Depletion of TSG101 forms a mammalian 'Class E' compartment: a multicisternal early endosome with multiple sorting defects. J Cell Sci 118: 3003-3017
11. Field MC, Gabernet-Castello C, Dacks JB (2006) Reconstructing the evolution of the endocytic system: insights from genomics and molecular cell biology In Origins and Evolution of Eukaryotic Endomembranes and Cytoskeleton, Jékely G (ed) pp. 309-334. Austin, TX: Eurekah/Landes Bioscience Press
12. Hierro A, Sun J, Rusnak AS, Kim J, Prag G, Emr SD, Hurley JH (2004) Structure of the ESCRT-II endosomal trafficking complex. Nature 431: 221-225
13. Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW,Weissman JS, O'Shea EK (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-691
14. Hurley JH, Emr SD (2006) The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct 35: 277-298
15. Katzmann DJ, Babst M, Emr SD (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106: 145-155
16. Katzmann DJ, Stefan CJ, Babst M, Emr SD (2003) Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol 162: 413-423
17. Kostelansky MS, Sun J, Lee S, Kim J, Ghirlando R, Hierro A, Emr SD, Hurley JH (2006) Structural and functional organization of the ESCRT-I trafficking complex. Cell 125: 113-126
18. Krishna SS, Majumdar I, Grishin NV (2003) Structural classification of zinc fingers: survey and summary. Nucleic Acids Res 31: 532-550
19. Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrin-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440: 637-643
20. Landau M, Mayrose I, Rosenberg Y, Glaser F, Martz E, Pupko T, Ben-Tal N (2005) ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res 33: W299-W302
21. Lin Y, Kimpler LA, Naismith TV, Lauer JM, Hanson PI (2005) Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. J Biol Chem 280: 12799-12809
22. Muziol T, Pineda-Molina E, Ravelli RB, Zamborlini A, Usami Y, Gottlinger H, Weissenhorn W (2006) Structural basis for budding by the ESCRT-III factor CHMP3. Dev Cell 10: 821-830
23. Pineda-Molina E, Belrhali H, Piefer AJ, Akula I, Bates P, Weissenhorn W (2006) The crystal structure of the C-terminal domain of Vps28 reveals a conserved surface required for Vps20 recruitment. Traffic 7: 1007-1016
24. Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, Babu MM, Mills IG, McMahon HT (2004) Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis. EMBO J 23: 4371-4383
25. Raiborg C, Wesche J, Malerod L, Stenmark H (2006) Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains. J Cell Sci 119: 2414-2424
26. Razi M, Futter CE (2006) Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. Mol Biol Cell 17: 3469-3483
27. Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S (2006) CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol 172: 1045-1056
28. Slagsvold T, Aasland R, Hirano S, Bache KG, Raiborg C, Trambaiolo D, Wakatsuki S, Stenmark H (2005) Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. J Biol Chem 280: 19600-19606
29. Slagsvold T, Pattni K, Malerod L, Stenmark H (2006) Endosomal and non-endosomal functions of ESCRT proteins. Trends Cell Biol 16: 317-326
30. Tan S (2001) A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli. Protein Expr Purif 21: 224-234
31. Teo H, Gill DJ, Sun J, Perisic O, Veprintsev DB, Vallis Y, Emr SD, Williams RL (2006) ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell 125: 99-111
32. Teo H, Perisic O, Gonzalez B, Williams RL (2004) ESCRT-II, an endosome-associated complex required for protein sorting; crystal structure and interactions with ESCRT-III and membranes. Dev Cell 7: 559-569
33. Wang B, Alam SL, Meyer HH, Payne M, Stemmler TL, Davis DR, Sundquist WI (2003) Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J Biol Chem 278: 20225-20234
34. Whitley P, Reaves BJ, Hashimoto M, Riley AM, Potter BVL, Holman GD (2003) Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization. J Biol Chem 278: 38786-38795
35. Yorikawa C, Shibata H, Waguri S, Hatta K, Horii M, Katoh K, Kobayashi T, Uchiyama Y, Maki M (2005) Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRTII component EAP20 and regulates endosomal cargo sorting. Biochem J 387: 17-26