Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

Developmental Biology

Volumn 307, Issue 2, 2007, Pages 314-327

  Kim, Shinseog ^a,b   Bardwell, Vivian J ^a,b   Zarkower, David ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b Graduate Program in Biochemistry   (United States)

Author keywords

Autonomous; Conditional targeting; DMRT1; Gonocyte; Sertoli; Spermatogenesis; Testis

Indexed keywords

DOUBLESEX AND MAB 3 RELATED TRANSCRIPTION FACTOR 1; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL TYPE; CONTROLLED STUDY; GENE ACTIVITY; GENE EXPRESSION; GENE TARGETING; GERM CELL; KNOCKOUT MOUSE; MALE; MEIOSIS; MITOSIS; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; SEMINIFEROUS TUBULE; SERTOLI CELL; SPERMATOGENESIS; TESTIS;

CAENORHABDITIS ELEGANS; MUS; VERTEBRATA;

EID: 34347248432     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2007.04.046     Document Type: Article

References (46)

1. Adams I.R., and McLaren A. Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. Development 129 (2002) 1155-1164
2. Anderson R., Copeland T.K., Scholer H., Heasman J., and Wylie C. The onset of germ cell migration in the mouse embryo. Mech. Dev. 91 (2000) 61-68
3. Bowles J., Knight D., Smith C., Wilhelm D., Richman J., Mamiya S., Yashiro K., Chawengsaksophak K., Wilson M.J., Rossant J., Hamada H., and Koopman P. Retinoid signaling determines germ cell fate in mice. Science 312 (2006) 596-600
4. Bremner W.J., Millar M.R., Sharpe R.M., and Saunders P.T. Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens. Endocrinology 135 (1994) 1227-1234
5. Chang C., Chen Y.T., Yeh S.D., Xu Q., Wang R.S., Guillou F., Lardy H., and Yeh S. Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 6876-6881
6. Crocker M., Coghill S.B., and Cortinho R. An unbalanced autosomal translocation (7;9) associated with feminization. Clin. Genet. 34 (1988) 70-73
7. De Gendt K., Swinnen J.V., Saunders P.T., Schoonjans L., Dewerchin M., Devos A., Tan K., Atanassova N., Claessens F., Lecureuil C., Heyns W., Carmeliet P., Guillou F., Sharpe R.M., and Verhoeven G. A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 1327-1332
8. de Rooij D.G. Proliferation and differentiation of spermatogonial stem cells. Reproduction 121 (2001) 347-354
9. de Rooij D.G., and Russell L.D. All you wanted to know about spermatogonia but were afraid to ask. J. Androl. 21 (2000) 776-798
10. Erdman S.E., and Burtis K.C. The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. EMBO J. 12 (1993) 527-535
11. Fahrioglu U., Murphy M.M., Zarkower D., and Bardwell V.J. mRNA expression analysis and the molecular basis of neonatal testis defects in Dmrt1 mutant mice. Sex. Dev. 1 (2007) 42-58
12. Ginsburg M., Snow M.H., and McLaren A. Primordial germ cells in the mouse embryo during gastrulation. Development 110 (1990) 521-528
13. Griswold M.D. Interactions between germ cells and Sertoli cells in the testis. Biol. Reprod. 52 (1995) 211-216
14. Hess R.A., Cooke P.S., Hofmann M.C., and Murphy K.M. Mechanistic insights into the regulation of the spermatogonial stem cell niche. Cell Cycle 5 (2006) 1164-1170
15. Holdcraft R.W., and Braun R.E. Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids. Development 131 (2004) 459-467
16. Ion R., Telvi L., Chaussain J.L., Barbet J.P., Nunes M., Safar A., Rethore M.O., Fellous M., and McElreavey K. Failure of testicular development associated with a rearrangement of 9p24.1 proximal to the SNF2 gene. Hum. Genet. 102 (1998) 151-156
17. Kettlewell J.R., Raymond C.S., and Zarkower D. Temperature-dependent expression of turtle Dmrt1 prior to sexual differentiation. Genesis 26 (2000) 174-178
18. Kobayashi T., Matsuda M., Kajiura-Kobayashi H., Suzuki A., Saito N., Nakamoto M., Shibata N., and Nagahama Y. Two DM domain genes, DMY and DMRT1, involved in testicular differentiation and development in the medaka, Oryzias latipes. Dev. Dyn. 231 (2004) 518-526
19. Koshimizu U., Watanabe D., Sawada K., and Nishimune Y. A novel stage-specific differentiation antigen is expressed on mouse testicular germ cells during early meiotic prophase. Biol. Reprod. 49 (1993) 875-884
20. Lindeboom F., Gillemans N., Karis A., Jaegle M., Meijer D., Grosveld F., and Philipsen S. A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse. Nucleic Acids Res. 31 (2003) 5405-5412
21. Lomeli H., Ramos-Mejia V., Gertsenstein M., Lobe C.G., and Nagy A. Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells. Genesis 26 (2000) 116-117
22. Looijenga L.H., Hersmus R., Gillis A.J., Pfundt R., Stoop H.J., van Gurp R.J., Veltman J., Beverloo H.B., van Drunen E., van Kessel A.G., Pera R.R., Schneider D.T., Summersgill B., Shipley J., McIntyre A., van der Spek P., Schoenmakers E., and Oosterhuis J.W. Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res. 66 (2006) 290-302
23. Marchand O., Govoroun M., D'Cotta H., McMeel O., Lareyre J., Bernot A., Laudet V., and Guiguen Y. DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss. Biochim. Biophys. Acta 1493 (2000) 180-187
24. McLaren A. Gonad development: assembling the mammalian testis. Curr. Biol. 8 (1998) R175-R177
25. McLaren A., and Southee D. Entry of mouse embryonic germ cells into meiosis. Dev. Biol. 187 (1997) 107-113
26. McLean D.J., Friel P.J., Johnston D.S., and Griswold M.D. Characterization of spermatogonial stem cell maturation and differentiation in neonatal mice. Biol. Reprod. 69 (2003) 2085-2091
27. Moniot B., Berta P., Scherer G., Sudbeck P., and Poulat F. Male specific expression suggests role of DMRT1 in human sex determination. Mech. Dev. 91 (2000) 323-325
28. Nagano R., Tabata S., Nakanishi Y., Ohsako S., Kurohmaru M., and Hayashi Y. Reproliferation and relocation of mouse male germ cells (gonocytes) during prespermatogenesis. Anat. Rec. 258 (2000) 210-220
29. Ogata T., Muroya K., Matsuo N., Hata J., Fukushima Y., and Suzuki Y. Impaired male sex development in an infant with molecularly defined partial 9p monosomy: implication for a testis forming gene(s) on 9p. J. Med. Genet. 34 (1997) 331-334
30. Ohbo K., Yoshida S., Ohmura M., Ohneda O., Ogawa T., Tsuchiya H., Kuwana T., Kehler J., Abe K., Scholer H.R., and Suda T. Identification and characterization of stem cells in prepubertal spermatogenesis in mice small star, filled. Dev. Biol. 258 (2003) 209-225
31. Orth J.M., Qiu J., Jester Jr. W.F., and Pilder S. Expression of the c-kit gene is critical for migration of neonatal rat gonocytes in vitro. Biol. Reprod. 57 (1997) 676-683
32. Raymond C.S., Shamu C.E., Shen M.M., Seifert K.J., Hirsch B., Hodgkin J., and Zarkower D. Evidence for evolutionary conservation of sex-determining genes. Nature 391 (1998) 691-695
33. Raymond C.S., Kettlewell J.R., Hirsch B., Bardwell V.J., and Zarkower D. Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development. Dev. Biol. 215 (1999) 208-220
34. Raymond C.S., Parker E.D., Kettlewell J.R., Brown L.G., Page D.C., Kusz K., Jaruzelska J., Reinberg Y., Flejter W.L., Bardwell V.J., Hirsch B., and Zarkower D. A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators. Hum. Mol. Genet. 8 (1999) 989-996
35. Raymond C.S., Murphy M.W., O'Sullivan M.G., Bardwell V.J., and Zarkower D. Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation. Genes Dev. 14 (2000) 2587-2595
36. Sharpe R.M., McKinnell C., Kivlin C., and Fisher J.S. Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125 (2003) 769-784
37. Skinner M.K., Tung P.S., and Fritz I.B. Cooperativity between Sertoli cells and testicular peritubular cells in the production and deposition of extracellular matrix components. J. Cell Biol. 100 (1985) 1941-1947
38. Smith C.A., McClive P.J., Western P.S., Reed K.J., and Sinclair A.H. Conservation of a sex-determining gene. Nature 402 (1999) 601-602
39. Sreenivasulu K., Ganesh S., and Raman R. Evolutionarily conserved, DMRT1, encodes alternatively spliced transcripts and shows dimorphic expression during gonadal differentiation in the lizard, Calotes versicolor. Mech. Dev. 119 Suppl. 1 (2002) S55-S64
40. Tan K.A., De Gendt K., Atanassova N., Walker M., Sharpe R.M., Saunders P.T., Denolet E., and Verhoeven G. The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor. Endocrinology 146 (2005) 2674-2683
41. Tung P.S., and Fritz I.B. Morphogenetic restructuring and formation of basement membranes by Sertoli cells and testis peritubular cells in co-culture: inhibition of the morphogenetic cascade by cyclic AMP derivatives and by blocking direct cell contact. Dev. Biol. 120 (1987) 139-153
42. Vergouwen R.P., Jacobs S.G., Huiskamp R., Davids J.A., and de Rooij D.G. Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice. J. Reprod. Fertil. 93 (1991) 233-243
43. Watanabe D., Sawada K., Koshimizu U., Kagawa T., and Nishimune Y. Characterization of male meiotic germ cell-specific antigen (Meg 1) by monoclonal antibody TRA 369 in mice. Mol. Reprod. Dev. 33 (1992) 307-312
44. Wu J., Jester Jr. W.F., and Orth J.M. Short-type PB-cadherin promotes survival of gonocytes and activates JAK-STAT signalling. Dev. Biol. 284 (2005) 437-450
45. Xia W., Zhou L., Yao B., Li C.J., and Gui J.F. Differential and spermatogenic cell-specific expression of DMRT1 during sex reversal in protogynous hermaphroditic groupers. Mol. Cell. Endocrinol. 263 (2007) 156-172
46. Zarkower D. Establishing sexual dimorphism: conservation amidst diversity?. Nat. Rev., Genet 2 (2001) 175-185