Direct palladium-catalyzed alkynylation of N-fused heterocycles

Journal of the American Chemical Society

Volumn 129, Issue 25, 2007, Pages 7742-7743

  Seregin, Ilya V ^a   Ryabova, Victoria ^a   Gevorgyan, Vladimir ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCYCLIC COMPOUND; PALLADIUM;

ALKYNYLATION; ARTICLE; ARYLATION; CATALYSIS; CROSS COUPLING REACTION; HYDROGEN BOND; REACTION ANALYSIS;

CATALYSIS; HETEROCYCLIC COMPOUNDS; PALLADIUM;

EID: 34347241643     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja072718l     Document Type: Article

References (41)

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37. Trial attempts with non-fused heterocycles, such as pyrroles, under these reaction conditions, afforded low yields of the corresponding alkynylation products. Further studies on the scope of this transformation are underway in our group.
38. For preparation of bromoalkynes, see Supporting Information.
39. See Supporting Information for details.
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41. The reaction was stopped at 60% conversion to avoid thermal decomposition of the product.