-
1
-
-
0033570079
-
A fluorescence-based highperformance liquid chromatographic assay to determine acid ceramidase activity
-
He X, Li CM, Park JH, Dagan A, Gatt S, Schuchman EH: A fluorescence-based highperformance liquid chromatographic assay to determine acid ceramidase activity. Anal Biochem 1999;274:264-269.
-
(1999)
Anal Biochem
, vol.274
, pp. 264-269
-
-
He, X.1
Li, C.M.2
Park, J.H.3
Dagan, A.4
Gatt, S.5
Schuchman, E.H.6
-
2
-
-
0032744715
-
Purification of acid ceramidase from human placenta
-
Linke T, Lansmann S, Sandhoff K: Purification of acid ceramidase from human placenta. Methods Enzymol 2000;311:201-207.
-
(2000)
Methods Enzymol
, vol.311
, pp. 201-207
-
-
Linke, T.1
Lansmann, S.2
Sandhoff, K.3
-
3
-
-
0020378285
-
Substrate-specificities of acid and alkaline ceramidases in fibroblasts from patients with Farber disease and controls
-
Momoi T, Ben Yoseph Y, Nadler HL: Substrate-specificities of acid and alkaline ceramidases in fibroblasts from patients with Farber disease and controls. Biochem J 1982;205:419-425.
-
(1982)
Biochem J
, vol.205
, pp. 419-425
-
-
Momoi, T.1
Ben Yoseph, Y.2
Nadler, H.L.3
-
4
-
-
0030479325
-
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease
-
Koch J, Gartner S, Li CM, Quintern LE, Bernardo K, Levran O, Schnabel D, Desnick RJ, Schuchman EH, Sandhoff K: Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease. J Biol Chem 1996;271:33110-33115.
-
(1996)
J Biol Chem
, vol.271
, pp. 33110-33115
-
-
Koch, J.1
Gartner, S.2
Li, C.M.3
Quintern, L.E.4
Bernardo, K.5
Levran, O.6
Schnabel, D.7
Desnick, R.J.8
Schuchman, E.H.9
Sandhoff, K.10
-
5
-
-
0033795330
-
Human acid ceramidase gene: Novel mutations in Farber disease
-
Zhang Z, Mandal AK, Mital A, Popescu N, Zimonjic D, Moser A, Moser H, Mukherjee AB: Human acid ceramidase gene: novel mutations in Farber disease. Mol Genet Metab 2000;70:301-309.
-
(2000)
Mol Genet Metab
, vol.70
, pp. 301-309
-
-
Zhang, Z.1
Mandal, A.K.2
Mital, A.3
Popescu, N.4
Zimonjic, D.5
Moser, A.6
Moser, H.7
Mukherjee, A.B.8
-
6
-
-
0034647935
-
Molecular cloning and characterization of a human mitochondrial ceramidase
-
El Bawab S, Roddy P, Qian T, Bielawska A, Lemasters JJ, Hannun YA: Molecular cloning and characterization of a human mitochondrial ceramidase. J Biol Chem 2000;275:21508-21513.
-
(2000)
J Biol Chem
, vol.275
, pp. 21508-21513
-
-
El Bawab, S.1
Roddy, P.2
Qian, T.3
Bielawska, A.4
Lemasters, J.J.5
Hannun, Y.A.6
-
7
-
-
17444368619
-
Subcellular localization of human neutral ceramidase expressed in HEK293 cells
-
Hwang YH, Tani M, Nakagawa T, Okino N, Ito M: Subcellular localization of human neutral ceramidase expressed in HEK293 cells. Biochem Biophys Res Commun 2005;331:37-42.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 37-42
-
-
Hwang, Y.H.1
Tani, M.2
Nakagawa, T.3
Okino, N.4
Ito, M.5
-
8
-
-
0035854766
-
Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide
-
Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM: Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide. J Biol Chem 2001;276:26577-26588.
-
(2001)
J Biol Chem
, vol.276
, pp. 26577-26588
-
-
Mao, C.1
Xu, R.2
Szulc, Z.M.3
Bielawska, A.4
Galadari, S.H.5
Obeid, L.M.6
-
9
-
-
0043234296
-
Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: An enzyme that preferentially regulates metabolism of very long chain ceramides
-
Mao C, Xu R, Szulc ZM, Bielawski J, Becker KP, Bielawska A, Galadari SH, Hu W, Obeid LM: Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides. J Biol Chem 2003;278:31184-31191.
-
(2003)
J Biol Chem
, vol.278
, pp. 31184-31191
-
-
Mao, C.1
Xu, R.2
Szulc, Z.M.3
Bielawski, J.4
Becker, K.P.5
Bielawska, A.6
Galadari, S.H.7
Hu, W.8
Obeid, L.M.9
-
10
-
-
33646758184
-
Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis
-
Houben E, Holleran WM, Yaginuma T, Mao C, Obeid LM, Rogiers V, Takagi Y, Elias PM, Uchida Y: Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis. J Lipid Res 2006;47:1063-1070.
-
(2006)
J Lipid Res
, vol.47
, pp. 1063-1070
-
-
Houben, E.1
Holleran, W.M.2
Yaginuma, T.3
Mao, C.4
Obeid, L.M.5
Rogiers, V.6
Takagi, Y.7
Elias, P.M.8
Uchida, Y.9
-
11
-
-
0028303749
-
Keratinocyte differentiation is induced by cell-permeant ceramides and its proliferation is promoted by sphingosine
-
Wakita H, Tokura Y, Yagi H, Nishimura K, Furukawa F, Takigawa M: Keratinocyte differentiation is induced by cell-permeant ceramides and its proliferation is promoted by sphingosine. Arch Dermatol Res 1994;286:350-354.
-
(1994)
Arch Dermatol Res
, vol.286
, pp. 350-354
-
-
Wakita, H.1
Tokura, Y.2
Yagi, H.3
Nishimura, K.4
Furukawa, F.5
Takigawa, M.6
-
12
-
-
0031898446
-
A potential role for ceramide in the regulation of mouse epidermal keratinocyte proliferation and differentiation
-
Jung EM, Griner RD, Mann-Blakeney R, Bollag WB: A potential role for ceramide in the regulation of mouse epidermal keratinocyte proliferation and differentiation. J Invest Dermatol 1998;110:318-323.
-
(1998)
J Invest Dermatol
, vol.110
, pp. 318-323
-
-
Jung, E.M.1
Griner, R.D.2
Mann-Blakeney, R.3
Bollag, W.B.4
-
13
-
-
0031816571
-
Variable expression of apoptotic phenotype in keratinocytes treated with ultraviolet radiation, ceramide, or suspended in semisolid methylcellulose
-
Gniadecki R, Gajkowska B, Bartosik J, Hansen M, Wulf HC: Variable expression of apoptotic phenotype in keratinocytes treated with ultraviolet radiation, ceramide, or suspended in semisolid methylcellulose. Acta Derm Venereol 1998;78:248-257.
-
(1998)
Acta Derm Venereol
, vol.78
, pp. 248-257
-
-
Gniadecki, R.1
Gajkowska, B.2
Bartosik, J.3
Hansen, M.4
Wulf, H.C.5
-
14
-
-
0031735115
-
Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT
-
Bektas M, Dullin Y, Wieder T, Kolter T, Sandhoff K, Brossmer R, Ihrig P, Orfanos CE, Geilen CC: Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT. Exp Dermatol 1998;7:342-349.
-
(1998)
Exp Dermatol
, vol.7
, pp. 342-349
-
-
Bektas, M.1
Dullin, Y.2
Wieder, T.3
Kolter, T.4
Sandhoff, K.5
Brossmer, R.6
Ihrig, P.7
Orfanos, C.E.8
Geilen, C.C.9
-
15
-
-
0032939630
-
Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: Comparison between keratinocytes and HL-60 cells
-
Pillai S, Mahajan M, Carlomusto M: Ceramide potentiates, but sphingomyelin inhibits, vitamin D-induced keratinocyte differentiation: comparison between keratinocytes and HL-60 cells. Arch Dermatol Res 1999;291:284-289.
-
(1999)
Arch Dermatol Res
, vol.291
, pp. 284-289
-
-
Pillai, S.1
Mahajan, M.2
Carlomusto, M.3
-
17
-
-
0033796148
-
Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes
-
Di Nardo A, Benassi L, Magnoni C, Cossarizza A, Seidenari S, Giannetti A: Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes. Br J Dermatol 2000;143:491-497.
-
(2000)
Br J Dermatol
, vol.143
, pp. 491-497
-
-
Di Nardo, A.1
Benassi, L.2
Magnoni, C.3
Cossarizza, A.4
Seidenari, S.5
Giannetti, A.6
-
18
-
-
0033607517
-
Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells
-
Xia P, Wang L, Gamble JR, Vadas MA: Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. J Biol Chem 1999;274:34499-34505.
-
(1999)
J Biol Chem
, vol.274
, pp. 34499-34505
-
-
Xia, P.1
Wang, L.2
Gamble, J.R.3
Vadas, M.A.4
-
20
-
-
0037378439
-
Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing
-
Vogler R, Sauer B, Kim DS, Schafer-Korting M, Kleuser B: Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing. J Invest Dermatol 2003;120:693-700.
-
(2003)
J Invest Dermatol
, vol.120
, pp. 693-700
-
-
Vogler, R.1
Sauer, B.2
Kim, D.S.3
Schafer-Korting, M.4
Kleuser, B.5
-
21
-
-
4644268278
-
Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes
-
Sauer B, Vogler R, von Wenckstern H, Fujii M, Anzano MB, Glick AB, Schafer-Korting M, Roberts AB, Kleuser B: Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes. J Biol Chem 2004;279:38471-38479.
-
(2004)
J Biol Chem
, vol.279
, pp. 38471-38479
-
-
Sauer, B.1
Vogler, R.2
von Wenckstern, H.3
Fujii, M.4
Anzano, M.B.5
Glick, A.B.6
Schafer-Korting, M.7
Roberts, A.B.8
Kleuser, B.9
-
22
-
-
4344702204
-
Glucocorticoids mediate differential anti-apoptotic effects in human fibroblasts and keratinocytes via sphingosine-1-phosphate formation
-
Hammer S, Sauer B, Spika I, Schraut C, Kleuser B, Schafer-Korting M: Glucocorticoids mediate differential anti-apoptotic effects in human fibroblasts and keratinocytes via sphingosine-1-phosphate formation. J Cell Biochem 2004;91:840-851.
-
(2004)
J Cell Biochem
, vol.91
, pp. 840-851
-
-
Hammer, S.1
Sauer, B.2
Spika, I.3
Schraut, C.4
Kleuser, B.5
Schafer-Korting, M.6
-
23
-
-
0023036582
-
Biosynthesis of longchain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s)
-
Merrill AH, Wang E: Biosynthesis of longchain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s). J Biol Chem 1986;261:3764-3769.
-
(1986)
J Biol Chem
, vol.261
, pp. 3764-3769
-
-
Merrill, A.H.1
Wang, E.2
-
24
-
-
0027074149
-
Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells
-
Rother J, van Echten G, Schwarzmann G, Sandhoff K: Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells. Biochem Biophys Res Commun 1992;189:14-20.
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 14-20
-
-
Rother, J.1
van Echten, G.2
Schwarzmann, G.3
Sandhoff, K.4
-
25
-
-
0026265525
-
Structural and lipid biochemical correlates of the epidermal permeability barrier
-
Elias PM, Menon GK: Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 1991;24:1-26.
-
(1991)
Adv Lipid Res
, vol.24
, pp. 1-26
-
-
Elias, P.M.1
Menon, G.K.2
-
26
-
-
0026693975
-
Lipids and the epidermal water barrier: Metabolism, regulation, and pathophysiology
-
Elias PM, Feingold KR: Lipids and the epidermal water barrier: metabolism, regulation, and pathophysiology. Semin Dermatol 1992;11:176-182.
-
(1992)
Semin Dermatol
, vol.11
, pp. 176-182
-
-
Elias, P.M.1
Feingold, K.R.2
-
27
-
-
0029588535
-
Topical sphingolipids in antisepsis and antifungal therapy
-
Bibel DJ, Aly R, Shinefield HR: Topical sphingolipids in antisepsis and antifungal therapy. Clin Exp Dermatol 1995;20:395-400.
-
(1995)
Clin Exp Dermatol
, vol.20
, pp. 395-400
-
-
Bibel, D.J.1
Aly, R.2
Shinefield, H.R.3
-
28
-
-
0036036354
-
Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus
-
Arikawa J, Ishibashi M, Kawashima M, Takagi Y, Ichikawa Y, Imokawa G: Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus . J Invest Dermatol 2002;119:433-439.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 433-439
-
-
Arikawa, J.1
Ishibashi, M.2
Kawashima, M.3
Takagi, Y.4
Ichikawa, Y.5
Imokawa, G.6
-
29
-
-
0036206513
-
Synthesis of a novel fluorescent ceramide analogue and its use in the characterization of recombinant ceramidase from Pseudomonas aeruginosa PA01
-
Nieuwenhuizen WF, van Leeuwen S, Gotz F, Egmond MR: Synthesis of a novel fluorescent ceramide analogue and its use in the characterization of recombinant ceramidase from Pseudomonas aeruginosa PA01. Chem Phys Lipids 2002;114:181-191.
-
(2002)
Chem Phys Lipids
, vol.114
, pp. 181-191
-
-
Nieuwenhuizen, W.F.1
van Leeuwen, S.2
Gotz, F.3
Egmond, M.R.4
-
30
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of proteindye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of proteindye binding. Anal Biochem 1976;72:248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
31
-
-
0025303634
-
Ceramidase activity in porcine epidermis
-
Wertz PW, Downing DT: Ceramidase activity in porcine epidermis. FEBS Lett 1990;268:110-112.
-
(1990)
FEBS Lett
, vol.268
, pp. 110-112
-
-
Wertz, P.W.1
Downing, D.T.2
-
32
-
-
0029070835
-
Purification and biochemical characterization of membrane-bound epidermal ceramidases from guinea pig skin
-
Yada Y, Higuchi K, Imokawa G: Purification and biochemical characterization of membrane-bound epidermal ceramidases from guinea pig skin. J Biol Chem 1995;270:12677-12684.
-
(1995)
J Biol Chem
, vol.270
, pp. 12677-12684
-
-
Yada, Y.1
Higuchi, K.2
Imokawa, G.3
-
33
-
-
0029070822
-
Purification, characterization, and biosynthesis of human acid ceramidase
-
Bernardo K, Hurwitz R, Zenk T, Desnick RJ, Ferlinz K, Schuchman EH, Sandhoff K: Purification, characterization, and biosynthesis of human acid ceramidase. J Biol Chem 1995;270:11098-11102.
-
(1995)
J Biol Chem
, vol.270
, pp. 11098-11102
-
-
Bernardo, K.1
Hurwitz, R.2
Zenk, T.3
Desnick, R.J.4
Ferlinz, K.5
Schuchman, E.H.6
Sandhoff, K.7
-
34
-
-
0346668341
-
NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging
-
Behne MJ, Meyer JW, Hanson KM, Barry NP, Murata S, Crumrine D, Clegg RW, Gratton E, Holleran WM, Elias PM, Mauro TM: NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging. J Biol Chem 2002;277:47399-47406.
-
(2002)
J Biol Chem
, vol.277
, pp. 47399-47406
-
-
Behne, M.J.1
Meyer, J.W.2
Hanson, K.M.3
Barry, N.P.4
Murata, S.5
Crumrine, D.6
Clegg, R.W.7
Gratton, E.8
Holleran, W.M.9
Elias, P.M.10
Mauro, T.M.11
-
35
-
-
0038806397
-
Neonatal development of the stratum corneum pH gradient: Localization and mechanisms leading to emergence of optimal barrier function
-
Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM: Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol 2003;120:998-1006.
-
(2003)
J Invest Dermatol
, vol.120
, pp. 998-1006
-
-
Behne, M.J.1
Barry, N.P.2
Hanson, K.M.3
Aronchik, I.4
Clegg, R.W.5
Gratton, E.6
Feingold, K.7
Holleran, W.M.8
Elias, P.M.9
Mauro, T.M.10
|