Stability of antimicrobial decapeptide (KSL) and its analogues for delivery in the oral cavity

Pharmaceutical Research

Volumn 24, Issue 8, 2007, Pages 1544-1550

  Na, Dong Hee ^a   Faraj, Jabar ^b   Capan, Yilmaz ^c   Leung, Kai P ^d   DeLuca, Patrick P ^b  

^a Kyungsung University   (South Korea)

^b University of Kentucky   (United States)

^c HACETTEPE UNIVERSITY   (Turkey)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

Antimicrobial peptide; Antiplaque agent; Chewing gum; Peptide analogue; Stability

Indexed keywords

ANTIINFECTIVE AGENT; LYSYLLYSYLVALYLVALYLPHENYLALANINAMIDE; LYSYLLYSYLVALYLVALYLPHENYLALANYLLYSINAMIDE; LYSYLLYSYLVALYLVALYLPHENYLALANYLTRYPTOPHYLVALYLLYSYLPHENYLALANYL LYSINAMIDE; LYSYLVALYLLYSYLPHENYLALANYLLYSINAMIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; VALYLLYSYLPHENYLALANYLLYSINAMIDE;

ACTINOMYCES NAESLUNDII; ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CHEWING GUM; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG STABILITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LACTOBACILLUS ACIDOPHILUS; MALE; MOUTH CAVITY; MOUTH FLORA; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SALIVA; SOLID; STOMACH JUICE; STREPTOCOCCUS MUTANS; STREPTOCOCCUS SALIVARIUS; STREPTOCOCCUS SOBRINUS;

ADMINISTRATION, ORAL; AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CHEWING GUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DENTAL PLAQUE; DEPSIPEPTIDES; DRUG STABILITY; GASTRIC JUICE; HUMANS; KINETICS; LYSINE; MASS SPECTROMETRY; METHYLATION; MICROBIAL SENSITIVITY TESTS; SALIVA;

EID: 34250888750     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-007-9274-8     Document Type: Article

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