Effects of venous needle turbulence during ex vivo hemodialysis on endothelial morphology and nitric oxide formation

Journal of Biomechanics

Volumn 40, Issue 10, 2007, Pages 2158-2166

  Huynh, Thanh N ^a   Chacko, Balu K ^b   Teng, Xinjun ^b   Brott, Brigitta C ^c   Allon, Michael ^d   Kelpke, Stacey S ^e   Thompson, John A ^e   Patel, Rakesh P ^b   Anayiotos, Andreas S ^a  

^a and Radiation Oncology   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Alabama at Birmingham   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

Endothelial cells; Hemodialysis; Intimal hyperplasia; Needle turbulence; Nitric oxide

Indexed keywords

CELL CULTURE; ENDOTHELIAL CELLS; GRAFT VS. HOST REACTIONS; NITRIC OXIDE;

BOVINE AORTIC ENDOTHELIAL CELLS (BAEC); INTIMAL HYPERPLASIA (IH); NEEDLE TURBULENCE;

HEMODYNAMICS;

NITRIC OXIDE;

ARTERIOVENOUS FISTULA; ARTERY COMPLIANCE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; COW; ENDOTHELIUM CELL; GRAFT FAILURE; HEMODIALYSIS; INHIBITION KINETICS; MATHEMATICAL COMPUTING; NEEDLE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SIMULATION; SMOOTH MUSCLE FIBER; TURBULENT FLOW; VASOMOTOR DISORDER; VEIN BLOOD FLOW;

ANIMALS; AORTA; BLOOD VESSEL PROSTHESIS; CATTLE; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; HYPERPLASIA; MODELS, CARDIOVASCULAR; NEEDLES; NITRIC OXIDE; RENAL DIALYSIS; TUNICA INTIMA;

EID: 34250886285     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2006.10.028     Document Type: Article

References (77)

1. Azuma H., Ishikawa M., and Sekizaki S. Endothelium-dependent inhibition of platelet aggregation. British Journal of Pharmacology 88 (1986) 441-445
2. Barbato J.E., and Tzeng E. Nitric oxide and arterial disease. Journal of Vascular Surgery 40 (2004) 187-193
3. Bath P., Hassall D., Gladwin A., Palmer R., and Martin J. Nitric oxide and prostacyclin. Divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro. Arteriosclerosis and Thrombosis 11 (1991) 254-260
4. Bay W., Van Cleef S., and Owens M. The hemodialysis access: preferences and concerns of patients, dialysis nurses and technicians, and physicians. American Journal of Nephrology 54 (1998) 379-383
5. Boo Y., and Jo H. Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. American Journal of Physiology Cell Physiology 285 (2003) C499-C508
6. Boo Y., Sorescu G., Bauer P., Fulton D., Kemp B., Harrison D., Sessa W., and Jo H. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. Free Radical Biology Medicine 35 (2003) 729-741
7. Cai H., McNally J., Weber M., and Harrison D. Oscillatory shear stress upregulation of endothelial nitric oxide synthase requires intracellular hydrogen peroxide and CaMKII. Journal of Molecular and Cell Cardiology 37 (2004) 121-125
8. Chiu J., Lee P., Chen C., Lee C., Chang S., Chen L., Lien S., Ko Y., Usami S., and Chien S. Shear stress increases ICAM-1 and decreases VCAM-1 and E-selection expressions induced by tumor necrosis factor-[alpha] in endothelial cells. Arteriosclerosis and Thrombosis Vascular Biology 24 (2004) 73-79
9. Chiu J., Wang D., Chien S., Skalak R., and Usami S. Effects of disturbed flow on endothelial cells. Journal of Biomechanical Engineering 120 (1998) 2-8
10. Conlon P., Schwab S., and Nicholson M. Hemodialysis: Practices and Problems (2000), Oxford University Press, New York, NY
11. Davies M., and Hagen P. Pathobiology of intimal hyperplasia. British Journal of Surgery 81 (1994)
12. Davies, P., Remuzzi, A., Gordon, E., Dewey, C.J., Gimbrone, M., 1986. Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro. In: Proceedings of the National Academy of Science, vol. 7, pp. 2114-2117.
13. Davis C.F.J., Ley K., and Sarembock I.J. The role of inflammation in vascular injury and repair. Journal of Thrombosis and Haemostasis 8 (2003) 1699-1709
14. De Caterina R., Libby P., Peng H.-B., Thannickal V., Rajavashisth T., Gimbrone M.J., Shin W., and Liao J. Nitric oxide decreases cytokine-induced endothelial activation: nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. Journal of Clinical Investigation 96 (1995) 60-68
15. Dewey C., Bussolari Jr. S.R., and Davies P.F. The dynamic response of vascular endothelial cells to fluid shear stress. Journal of Biomechanical Engineering (1981) 177-185
16. Dhingra R., Young E.W., Hulbert-Shearon T., Leavey S., and Port F. Type of vascular access and mortality in US hemodialysis patients. Kidney International 60 (2001) 1443-1451
17. Dilley R.J., McGeachie J.K., and Tennant M. Vein to artery grafts: a morphological and histochemical study of the histogenesis of intimal hyperplasia. Australian and New Zealand Journal of Surgery 62 (1992) 223-235
18. Dimmeler S., and Zeiher A.M. Nitric oxide-an endothelial cell survival factor. Cellular Death and Differentiation 6 (1999) 964-968
19. Dobrin P.B., Littooy F.N., and Endean E.D. Mechanical factors predisposing to intimal hyperplasia and medial thickening in autogenous vein grafts. Surgery 105 (1989) 393-400
20. Ezzahiri R., Lemson M., Kitslaar P., Leunissen K., and Tordoir J. Haemodialysis vascular access and fistula surveillance methods in The Netherlands. Nephrology Dialysis Transplantation 14 (1999) 2110-2115
21. Fillinger M., Reinitz E., Schwartz R., Resetarits D., Paskanik A., Bruch D., and Bredenberg C. Graft geometry and venous intimal-medial hyperplasia in arteriovenous loop grafts. Journal of Vascular Surgery 4 (1990) 556-566
22. Franke R., Grafe M., Schnittler H., Seiffge D., Mittermayer C., and Drenckhahn D. Induction of human vascular endothelial stress fibres by fluid shear stress. Nature 307 (1984)
23. Freyberg M., Kaiser D., Graf R., Vischer P., and Friedl P. Integrin-associated protein and thrombospondin-1 as endothelial mechanosensitive death mediators. Biochemical and Biophysical Research Communications 271 (2000) 584-588
24. Freyberg M., Kaiser D., Graf R., Buttenbender J., and Friedl P. Proatherogenic flow conditions initiate endothelial apoptosis via thrombospondin-1 and the integrin-associated protein. Biochemical and Biophysical Research Communications 286 (2001) 141-149
25. Freyberg M., Kaiser D., Graf R., and Friedl P. Vascular endothelial cells express a functional fas-receptor due to lack of hemodynamic forces. Apoptosis 6 (2001) 339-343
26. Galbraith C., Skalak R., and Chien S. Shear stress induces spatial reorganization of the endothelial cell cytoskeleton. Cell Motility and the Cytoskeleton (1998) 317-330
27. Garg U.C., and Hassid H.A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. Journal of Clinical Investigation 83 (1989) 1774-1777
28. Gauthier T., Scalia R., Murohara T., Guo J., and Lefer A. Nitric oxide protects against leukocyte-endothelium interactions in the early stages of hypercholesterolemia. Arteriosclerosis and Thrombosis Vascular Biology 15 (1995) 1652-1659
29. Go Y., Patel R., Maland M., Park H., Beckman J., Darley-Usmar V., and Jo H. Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. American Journal of Physiology 277 (1999) H1647-H1653
30. Go Y., Boo Y., Park H., Maland M., Patel R., Pritchard K.J., Fujio Y., Walsh K., Darley-Usmar V., and Jo H. Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress. Journal of Applied Physiology 91 (2001) 1574-1581
31. Goodkin D.A., Bragg-Gresham J.L., Koenig K.G., Wolfe R.A., Akiba T., Andreucci V.E., Saito A., Rayner H.C., Kurokawa K., Port F.K., et al. Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the dialysis outcomes and practice patterns study (DOPPS). Journal of the American Society of Nephrology 14 (2003) 235-246
32. Graf R., Apenberg S., Freyberg M., and Fried P. A common mechanism for the mechanosensitive regulation of apoptosis in different cell types and for different mechanical stimuli. Apoptosis (2003) 531-538
33. Grisham M.B., Johnson G.G., and Lancaster Jr. J.R. Quantitation of nitrate and nitrite in extracellular fluids. Methods in Enzymology 268 (1996) 237-246
34. Groves P., Banning A., Penny W., Newby A., Cheadle H., and Lewis M. The effects of exogenous nitric oxide on smooth muscle cell proliferation following porcine carotid angioplasty. Cardiovascular Research 30 (1996) 87-96
35. Hakim R., and Himmelfarb J. Hemodialysis access failure: a call to action. Kidney International 51 (1998) 1029-1040
36. Hoffmann J., Haendeler J., Aicher A., Rossig L., Vasa M., and Zeiher A.M. Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide. Circulation and Respiratory 89 (2001) 709-715
37. Ishiwata S., Tukada T., Nakanishi S., Nishiyama S., and Seki A. Postangioplasty restenosis: platelet activation and the coagulation-fibrinolysis system as possible factors in the pathogenesis of restenosis. American Heart Journal 133 (1997) 387-392
38. Kanterman R., Vesely T., Pilgram T., Guy B., Windus D., and Picus D. Dialysis access grafts: anatomic location of venous stenosis and results of angioplasty. Radiology 13 (1995) 135-139
39. Kibbe M.R., Li J., and Nie S. Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate. Journal of Vascular Surgery 31 (2000) 1214-1228
40. Kolpakov V., Gordon D., and Kulik T. Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circulation Research 76 (1995) 305-309
41. Kotamraju S., Hogg N., Joseph J., Keefer L.K., and Kalyanaraman B. Inhibition of oxidized low-density lipoprotein-induced apoptosis in endothelial cells by nitric oxide. Peroxyl radical scavenging as an antiapoptotic mechanism. Journal of Biological Chemistry 276 (2001) 17316-17323
42. Kubes, P., Suzuki, M., Granger, D.N., 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. In: Proceedings of the National Academy of Science USA, vol. 88, pp. 4651-4655.
43. Landmesser U., Harrison D., and Drexler H. Oxidant stress-a major cause of reduced endothelial nitric oxide availability in cardiovascular disease. European Journal of Clinical Pharmacology 62 (2006) 13-19
44. Lee M., David E., Makkar R., and Wilentz J. Molecular and cellular basis of restenosis after percutaneous coronary intervention: the intertwining roles of platelets, leucocytes, and the coagulation-fibrinolysis system. Journal of Pathology 203 (2004) 861-870
45. Lefer A.M. Nitric oxide: nature's naturally occurring leukocyte inhibitor. Circulation (1997) 553-554
46. Lemson M., Tordoir J., Daemen M., and Kitslaar P. Intimal hyperplasia in vascular grafts. European Journal Vascular and Endovascular Surgery 4 (2000) 336-350
47. Li S., Chen B.P., Azuma N., Hu Y.L., Wu S.Z., Sumpio B.E., Shyy J.Y., and Chien S. Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. Journal of Clinical Investigation 103 (1999) 1141-1150
48. Li C., Zeng Y., Hu J., and Yu H. Effects of fluid shear stress on expression of proto-oncogenes c-fos and c-myc in cultured human umbilical vein endothelial cells. Clinical Hemorheology and Microcirculation 26 (2002) 117-123
49. Lindner, V., Reidy, M., 1991. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. In: Proceedings of the National Academy of Science USA, vol. 7, pp. 37-39.
50. Lopez-Farre A., Rodriguez-Feo J.A., Sanchez D.M., Rico L., and Casado S. Role of nitric oxide in the control of apoptosis in the microvasculature. International Journal of Biochemical and Cellular Biology 30 (1998) 1095-1106
51. Loth F., Fischer P., Arslan N., Bertram C., Lee S., Royston T., Shaalan W., and Bassiouny H. Transitional flow at the venous anastomosis of an arteriovenous graft: potential activation of the ERK 1/2 mechanotransduction pathway. Journal of Biomechanical Engineering 125 (2003) 49-61
52. Marks D.S., Vita J.A., Folts J.D., Keaney Jr. J.F., Welch G.N., and Loscalzo J. Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide. Journal of Clinical Investigation 6 (1995) 2630-2638
53. McCarty M. Optimizing endothelial nitric oxide activity may slow endothelial aging. Medical Hypotheses 63 (2004) 719-723
54. Mellion B.T., Ignarro L.J., Ohlstein E.H., Pontecorvo E.G., Hyman A.L., and Kadowitz P.J. Evidence for the inhibitory role of guanosine 3′,5′-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators. Blood 57 (1981) 946-955
55. Moellering D., Levonen A., Go Y., Patel R., Dickinson D., Forman H., and Darley-Usmar V. Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection against quinone-mediated oxidative stress. Biochemical Journal Part 1 (2002) 51-59
56. Moreno M.R. Endothelial Expression of Endothelin and Prostacyclin in Response to Combined Flow-Induced Shear Stress and Pressure-Driven Cyclic Strain. Master Thesis (2004), Florida International University, Miami pp. 22-45
57. Moore Z.W.Q., and Hui D.Y. Apolipoprotein E inhibition of vascular hyperplasia and neointima formation requires inducible nitric oxide synthase. Journal of Lipid Research 46 (2005) 2083-2090
58. Noris M., Donadelli R., Aiello S., Foppolo M., Todeschini M., Orisio S., Remuzzi G., and Remuzzi A. Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions. Circulation research 76 (1995) 536-543
59. Pedroso P., Hershey B., Holman W., Venugopalan R., and Anayiotos A. The hemodynamic effects of compliance, bulging, and curvature in a saphenous vein coronary artery bypass graft model. Technological Health Care 11 (2003) 443-455
60. Pisoni R. Vascular access use and outcomes: results from the DOPPS. Contribution Nephrology (2002) 13-19
61. Pisoni R., Young E., and Dykstra D. Vascular access use in Europe and the United States: results from the DOPPS. Kidney International (2002) 305-316
62. Preli R., Klein K., and Herrington D. Vascular effects of dietary L-arginine supplementation. Atherosclerosis 162 (2002) 1-15
63. Qiu Y., and Tarbell J.M. Interaction between wall shear stress and circumferential strain affects endothelial cell biochemical production. Journal of Vascular Research 37 (2000) 147-157
64. Radomski M., Palmer R., and Moncada S. The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. British Journal of Pharmacology 92 (1987) 639-646
65. Radomski M., Palmer R., and Moncada S. The role of nitric oxide and cGMP in platelet adhesion molecules to vascular endothelium. Biochemical Biophysics Research Community 148 (1987) 1482-1489
66. Saran R., Dykstra D.M., Pisoni R.L., Akiba T., Akizawa T., Canaud B., Chen K., Piera L., Saito A., and Young E.W. Timing of first cannulation and vascular access failure in haemodialysis: an analysis of practice patterns at dialysis facilities in the DOPPS. Nephrology Dialysis Transplantation 19 (2004) 2334-2340
67. Sarkar R., Meinberg E., Stanley J., Gordon D., and Webb R. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells. Circular Research 78 (1996) 225-230
68. Schwab S., Harrington J., Singh A., Roher R., Shohaib S., Perrone R., Meyer K., and Beasley D. Vascular access for hemodialysis. Kidney International (1999) 2078-2090
69. Schwartz S.M. Smooth muscle migration in atherosclerosis and restenosis. Journal of Clinical Investigation 11 (1997) 87-89
70. Topper, J., Cai, J., Falb, D., Gimbrone, M.J., 1996. Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. In: Proceedings of the National Academy of Science USA, vol. 93, pp. 10417-10422.
71. Unnikrishnan S., Brott B., Huynh T., Cheng C., Ito Y., Allon M., and Anayiotos A. Turbulent flow evaluation of the venous needle during hemodialysis. Journal of Biomechanical Engineering 7 (2005) 1141-1146
72. von der Leyen HE G.G., Morishita R., Lewis N.P., Zhang L., Nakajima M., Kaneda Y., Cooke J.P., and Dzau V.J. In vivo gene transfer to prevent neointima hyperplasia after vascular injury: effect of overexpression of constitutive nitric oxide synthase. Proceedings of the National Academy of Sciences USA 10 (1995) 92-113
73. Weber M., Hagedorn C., Harrison D., and Searles C. Laminar shear stress and 3′ polyadenylation of eNOS mRNA. Circular Research 96 (2005) 1161-1168
74. Weibel E. Stereological Methods (1979), Academic Press, London, NY pp. 57-98
75. Wilensky R.L., March K.L., Gradus-Pizlo I., Sandusky G., Fineberg N., and Hathaway D.R. Vascular injury, repair, and restenosis after percutaneous transluminal angioplasty in the atherosclerotic rabbit. Circulation 92 (1995) 2995-3005
76. Wojciak-Stothard B., and Ridley A. Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. Journal of Cell Biology (2003) 429-439
77. Zarate A.R. New needle for two needle hemodialysis. ASAIO Journal 44 (1998) m549-m554