Effects of fluid shear stress on expression of proto-oncogenes c-fos and c-myc in cultured human umbilical vein endothelial cells

Clinical Hemorheology and Microcirculation

Volumn 26, Issue 2, 2002, Pages 117-123

  Li, Caixia ^a   Zeng, Yanjun ^a   Hu, Jinlin ^a   Yu, Hongmei ^a  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

c fos protein; c myc protein; Endothelial cells; Proto oncogene; Shear stress

Indexed keywords

MYC PROTEIN; PROTEIN C FOS;

ARTICLE; BASAL CELL; CELL ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; MEDICAL RESEARCH; ONCOGENE C FOS; ONCOGENE C MYC; ONSET AGE; PROTEIN BLOOD LEVEL; PROTO ONCOGENE; SHEAR STRESS; CELL CULTURE; CIRCULATION; CYTOLOGY; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; KINETICS; MECHANICAL STRESS; METABOLISM; PHYSIOLOGY; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

BLOOD CIRCULATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; KINETICS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-MYC; STRESS, MECHANICAL; UMBILICAL VEINS;

EID: 0036111842     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Effect of fluid shear stress on gene regulation of vascular cells
2. Fluid shear stress induces synthesis and nuclear localization of c-fos in culture human endothelial cells
3. Shear stress induced detachment of human polymorphonuclear leukocytes from endothelial cell monolayers
4. Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors
5. Pulsatile and steady flow induces c-fos expression in human endothelial cells
6. The Ras-JNK pathway is involved in shear-induced gene expression
7. Selective activation of the JNK signaling cascade and c-jun transcriptional activity by the small GTPases Rac and Cdc42Hs
8. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
9. Induction of proto-oncogene c-jun by serum growth factors
10. Regulation of genetic expression in shear stress-stimulated endothelial cell
11. Hemodynamic forces are complex regulators of endothelial gene expression