Microsatellite instability in poorly differentiated adenocarcinomas of the colon and rectum: Relationship to clinicopathological features

Journal of Clinical Pathology

Volumn 60, Issue 6, 2007, Pages 701-704

  Kazama, Yoshihiro ^a   Watanabe, Toshiaki ^a   Kanazawa, Takamitsu ^a   Tanaka, Junichiro ^a   Tanaka, Toshiaki ^a   Nagawa, Hirokazu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CLINICAL FEATURE; COLON ADENOCARCINOMA; CONTROLLED STUDY; FEMALE; GENE LOCUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; RECTUM CARCINOMA;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; CELL DIFFERENTIATION; COLORECTAL NEOPLASMS; DNA, NEOPLASM; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; SURVIVAL ANALYSIS;

EID: 34250873914     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2006.039081     Document Type: Article

References (20)

1. Hamilton SR, Aaltonen LA. Pathology and genetics; tumors of the digestive system. Lyon: IARC, 2000.
2. Chung CK, Zaino RJ, Stryker JA. Colorectal carcinoma: evaluation of histologic grade and factors influencing prognosis. J Surg Oncol 1982;21:143-8.
3. Umpleby HC, Bristol JB, Rainey JB, et al. Survival of 727 patients with single carcinomas of the large bowel. Dis Colon Rectum 1984;27:803-10.
4. Bjerkeset T, Morild I, Mork S, et al. Tumor characteristics in colorectal cancer and their relationship to treatment and prognosis. Dis Colon Rectum 1987;30:934-8.
5. Compton CC, Fielding LP, Burgart LJ, et al. Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000;124:979-94.
6. Gryfe R, Kim H, Hsieh ET, et al. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 2000;342:69-77.
7. Gafa R, Maestri I, Matteuzzi M, et al. Sporadic colorectal adenocarcinomas with high-frequency microsatellite instability. Cancer 2000;89:2025-37.
8. Goel A, Arnold CN, Niedzwiecki D, et al. Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res 2003;63:1608-14.
9. Ward R, Meagher A, Tomlinson I, et al. Microsatellite instability and the clinicopathological features of sporadic colorectal cancer. Gut 2001;48:821-9.
10. Kawabata Y, Tomita N, Monden T, et al. Molecular characteristics of poorly differentiated adenocarcinoma and signet-ring-cell carcinoma of colorectum. Int J Cancer 1999;84:33-8.
11. Hemminki A, Mecklin JP, Jarvinen H, et al. Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology 2000;119:921-8.
12. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
13. Vasen HF, Watson P, Mecklin JP, et al. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology 1999;116:1453-6.
14. Sobin LH. TNM, sixth edition: new developments in general concepts and rules. Semin Surg Oncol 2003;21:19-22.
15. Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-57.
16. Umetani N, Sasaki S, Watanabe T, et al. Diagnostic primer sets for microsatellite instability optimized for a minimal amount of damaged DNA from colorectal tissue samples. Ann Surg Oncol 2000;7:276-80.
17. Laiho P, Launonen V, Lahermo P, et al. Low-level microsatellite instability in most colorectal carcinomas. Cancer Res 2002;62:1166-70.
18. Cserni G. Nodal staging of colorectal carcinomas and sentinel nodes. J Clin Pathol 2003;56:327-35.
19. Ribic CM, Sargent DJ, Moore MJ, et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003;349:247-57.
20. Fallik D, Borrini F, Boige V, et al. Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer. Cancer Res 2003;63:5738- 44.