-
1
-
-
0032572912
-
Acute lymphoblastic leukemia
-
Pui C.H., and Evans W.E. Acute lymphoblastic leukemia. N Engl J Med 339 (1998) 605-615
-
(1998)
N Engl J Med
, vol.339
, pp. 605-615
-
-
Pui, C.H.1
Evans, W.E.2
-
2
-
-
0041629362
-
Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions
-
Verrills N.M., Flemming C.L., Liu M., Ivery M.T., Cobon G.S., Norris M.D., et al. Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions. Chem Biol 10 (2003) 597-607
-
(2003)
Chem Biol
, vol.10
, pp. 597-607
-
-
Verrills, N.M.1
Flemming, C.L.2
Liu, M.3
Ivery, M.T.4
Cobon, G.S.5
Norris, M.D.6
-
3
-
-
0033054696
-
Paclitaxel-induced apoptosis in Jurkat, a leukemic T cell line, is enhanced by ceramide
-
Myrick D., Blackinton D., Klostergaard J., Kouttab N., Maizel A., Wanebo H., et al. Paclitaxel-induced apoptosis in Jurkat, a leukemic T cell line, is enhanced by ceramide. Leuk Res 23 (1999) 569-578
-
(1999)
Leuk Res
, vol.23
, pp. 569-578
-
-
Myrick, D.1
Blackinton, D.2
Klostergaard, J.3
Kouttab, N.4
Maizel, A.5
Wanebo, H.6
-
4
-
-
0031043119
-
The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance
-
Kavallaris M. The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance. Anticancer Drugs 8 (1997) 17-25
-
(1997)
Anticancer Drugs
, vol.8
, pp. 17-25
-
-
Kavallaris, M.1
-
5
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
Bollag D.M., McQueney P.A., Zhu J., Hensens O., Koupal L., Liesch J., et al. Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res 55 (1995) 2325-2333
-
(1995)
Cancer Res
, vol.55
, pp. 2325-2333
-
-
Bollag, D.M.1
McQueney, P.A.2
Zhu, J.3
Hensens, O.4
Koupal, L.5
Liesch, J.6
-
6
-
-
0031027531
-
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
-
Kowalski R.J., Giannakakou P., and Hamel E. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J Biol Chem 272 (1997) 2534-2541
-
(1997)
J Biol Chem
, vol.272
, pp. 2534-2541
-
-
Kowalski, R.J.1
Giannakakou, P.2
Hamel, E.3
-
7
-
-
0030899009
-
Anthelmintics: a comparative review of their clinical pharmacology
-
De Silva N., Guyatt H., and Bundy D. Anthelmintics: a comparative review of their clinical pharmacology. Drugs 53 (1997) 769-788
-
(1997)
Drugs
, vol.53
, pp. 769-788
-
-
De Silva, N.1
Guyatt, H.2
Bundy, D.3
-
8
-
-
0018703882
-
The interaction of benzimidazole carbamates with mammalian microtobule protein
-
Ireland C.M., Gull K., Gutteridge W.E., and Pogson C.I. The interaction of benzimidazole carbamates with mammalian microtobule protein. Biochem Pharmacol 28 (1979) 2680-2682
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 2680-2682
-
-
Ireland, C.M.1
Gull, K.2
Gutteridge, W.E.3
Pogson, C.I.4
-
9
-
-
0034439133
-
Albendazole: a review of anthelmintic efficacy and safety in humans
-
Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology 121 Suppl (2000) S113-S132
-
(2000)
Parasitology
, vol.121
, Issue.SUPPL
-
-
Horton, J.1
-
10
-
-
17644414121
-
Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis
-
Pourgholami M.H., Akhter J., Wang L., Lu Y., and Morris D.L. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. Cancer Chemother Pharmacol 55 (2005) 425-432
-
(2005)
Cancer Chemother Pharmacol
, vol.55
, pp. 425-432
-
-
Pourgholami, M.H.1
Akhter, J.2
Wang, L.3
Lu, Y.4
Morris, D.L.5
-
11
-
-
33645661534
-
Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice
-
Pourgholami M.H., Yan Cai Z., Lu Y., Wang L., and Morris D.L. Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice. Clin Cancer Res 12 (2006) 1928-1935
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1928-1935
-
-
Pourgholami, M.H.1
Yan Cai, Z.2
Lu, Y.3
Wang, L.4
Morris, D.L.5
-
12
-
-
33744500237
-
Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL
-
Meyer L.H., Karawajew L., Schrappe M., Ludwig W.D., Debatin K.M., and Stahnke K. Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL. Blood 107 (2006) 4524-4531
-
(2006)
Blood
, vol.107
, pp. 4524-4531
-
-
Meyer, L.H.1
Karawajew, L.2
Schrappe, M.3
Ludwig, W.D.4
Debatin, K.M.5
Stahnke, K.6
-
13
-
-
0025738516
-
Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production
-
Vistica D.T., Skehan P., Scudiero D., Monks A., Pittman A., and Boyd M.R. Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production. Cancer Res 51 (1991) 2515-2520
-
(1991)
Cancer Res
, vol.51
, pp. 2515-2520
-
-
Vistica, D.T.1
Skehan, P.2
Scudiero, D.3
Monks, A.4
Pittman, A.5
Boyd, M.R.6
-
14
-
-
0344010620
-
Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients
-
Savli H., Sirma S., Nagy B., Aktan M., Dincol G., and Ozbek U. Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients. Exp Mol Med 35 (2003) 454-459
-
(2003)
Exp Mol Med
, vol.35
, pp. 454-459
-
-
Savli, H.1
Sirma, S.2
Nagy, B.3
Aktan, M.4
Dincol, G.5
Ozbek, U.6
-
15
-
-
24144450013
-
Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells
-
Faucher K., Rabinovitch-Chable H., Cook-Moreau J., Barriere G., Sturtz F., and Rigaud M. Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells. Mol Cell Biochem 277 (2005) 81-87
-
(2005)
Mol Cell Biochem
, vol.277
, pp. 81-87
-
-
Faucher, K.1
Rabinovitch-Chable, H.2
Cook-Moreau, J.3
Barriere, G.4
Sturtz, F.5
Rigaud, M.6
-
16
-
-
15044358997
-
The antiapoptotic member of the Bcl-2 family Mcl-1 is a CTL target in cancer patients
-
Andersen M.H., Becker J.C., and Thor Straten P. The antiapoptotic member of the Bcl-2 family Mcl-1 is a CTL target in cancer patients. Leukemia 19 (2005) 484-485
-
(2005)
Leukemia
, vol.19
, pp. 484-485
-
-
Andersen, M.H.1
Becker, J.C.2
Thor Straten, P.3
-
17
-
-
20044379059
-
Review: tubulin function, action of antitubulin drugs, and new drug development
-
Pellegrini F., and Budman D.R. Review: tubulin function, action of antitubulin drugs, and new drug development. Cancer Invest 23 (2005) 264-273
-
(2005)
Cancer Invest
, vol.23
, pp. 264-273
-
-
Pellegrini, F.1
Budman, D.R.2
-
19
-
-
33747878462
-
Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model
-
Hersey P., Zhuang L., and Zhang X.D. Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model. Int Rev Cytol 251 (2006) 131-158
-
(2006)
Int Rev Cytol
, vol.251
, pp. 131-158
-
-
Hersey, P.1
Zhuang, L.2
Zhang, X.D.3
-
20
-
-
0035036508
-
Caspase-3 apoptotic signaling following injury to the central nervous system
-
Springer J.E., Nottingham S.A., McEwen M.L., Azbill R.D., and Jin Y. Caspase-3 apoptotic signaling following injury to the central nervous system. Clin Chem Lab Med 39 (2001) 299-307
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 299-307
-
-
Springer, J.E.1
Nottingham, S.A.2
McEwen, M.L.3
Azbill, R.D.4
Jin, Y.5
-
21
-
-
0034077189
-
Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies
-
Wang J., and Lenardo M.J. Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies. J Cell Sci 113 Pt 5 (2000) 753-757
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 5
, pp. 753-757
-
-
Wang, J.1
Lenardo, M.J.2
-
22
-
-
0032576692
-
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
-
Rosse T., Olivier R., Monney L., Rager M., Conus S., Fellay I., et al. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature 391 (1998) 496-499
-
(1998)
Nature
, vol.391
, pp. 496-499
-
-
Rosse, T.1
Olivier, R.2
Monney, L.3
Rager, M.4
Conus, S.5
Fellay, I.6
-
23
-
-
0032168545
-
The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells
-
Amos C.L., Woetmann A., Nielsen M., Geisler C., Odum N., Brown B.L., et al. The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells. Cytokine 10 (1998) 662-668
-
(1998)
Cytokine
, vol.10
, pp. 662-668
-
-
Amos, C.L.1
Woetmann, A.2
Nielsen, M.3
Geisler, C.4
Odum, N.5
Brown, B.L.6
-
24
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
-
Liu X., Kim C.N., Yang J., Jemmerson R., and Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86 (1996) 147-157
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
25
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
-
Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275 (1997) 1129-1132
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
-
26
-
-
0031918223
-
Bcl-2 family: regulators of cell death
-
Chao D.T., and Korsmeyer S.J. Bcl-2 family: regulators of cell death. Annu Rev Immunol 16 (1998) 395-419
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
27
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3 (1997) 614-620
-
(1997)
Nat Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
28
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed J.C. Double identity for proteins of the Bcl-2 family. Nature 387 (1997) 773-776
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
29
-
-
0037085048
-
Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel
-
Kolfschoten G.M., Hulscher T.M., Duyndam M.C., Pinedo H.M., and Boven E. Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel. Biochem Pharmacol 63 (2002) 733-743
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 733-743
-
-
Kolfschoten, G.M.1
Hulscher, T.M.2
Duyndam, M.C.3
Pinedo, H.M.4
Boven, E.5
-
30
-
-
0035890335
-
Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate
-
Makin G.W., Corfe B.M., Griffiths G.J., Thistlethwaite A., Hickman J.A., and Dive C. Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate. Embo J 20 (2001) 6306-6315
-
(2001)
Embo J
, vol.20
, pp. 6306-6315
-
-
Makin, G.W.1
Corfe, B.M.2
Griffiths, G.J.3
Thistlethwaite, A.4
Hickman, J.A.5
Dive, C.6
-
32
-
-
0028972616
-
Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance
-
Reed J.C. Regulation of apoptosis by Bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 7 (1995) 541-546
-
(1995)
Curr Opin Oncol
, vol.7
, pp. 541-546
-
-
Reed, J.C.1
-
33
-
-
0033616709
-
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
-
Srivastava R.K., Mi Q.S., Hardwick J.M., and Longo D.L. Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Proc Natl Acad Sci USA 96 (1999) 3775-3780
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3775-3780
-
-
Srivastava, R.K.1
Mi, Q.S.2
Hardwick, J.M.3
Longo, D.L.4
-
34
-
-
0027130238
-
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death
-
Korsmeyer S.J., Shutter J.R., Veis D.J., Merry D.E., and Oltvai Z.N. Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Semin Cancer Biol 4 (1993) 327-332
-
(1993)
Semin Cancer Biol
, vol.4
, pp. 327-332
-
-
Korsmeyer, S.J.1
Shutter, J.R.2
Veis, D.J.3
Merry, D.E.4
Oltvai, Z.N.5
-
36
-
-
33750723137
-
Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
-
Yoshino T., Shiina H., Urakami S., Kikuno N., Yoneda T., Shigeno K., et al. Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy. Clin Cancer Res 12 (2006) 6116-6124
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6116-6124
-
-
Yoshino, T.1
Shiina, H.2
Urakami, S.3
Kikuno, N.4
Yoneda, T.5
Shigeno, K.6
-
37
-
-
0027480450
-
Mcl-1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2
-
Kozopas K.M., Yang T., Buchan H.L., Zhou P., and Craig R.W. Mcl-1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. Proc Natl Acad Sci USA 90 (1993) 3516-3520
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3516-3520
-
-
Kozopas, K.M.1
Yang, T.2
Buchan, H.L.3
Zhou, P.4
Craig, R.W.5
-
38
-
-
0032006805
-
Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse
-
Kaufmann S.H., Karp J.E., Svingen P.A., Krajewski S., Burke P.J., Gore S.D., et al. Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse. Blood 91 (1998) 991-1000
-
(1998)
Blood
, vol.91
, pp. 991-1000
-
-
Kaufmann, S.H.1
Karp, J.E.2
Svingen, P.A.3
Krajewski, S.4
Burke, P.J.5
Gore, S.D.6
-
40
-
-
0028958030
-
Bcl-2: prevention of apoptosis as a mechanism of drug resistance
-
Reed J.C. Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol Oncol Clin North Am 9 (1995) 451-473
-
(1995)
Hematol Oncol Clin North Am
, vol.9
, pp. 451-473
-
-
Reed, J.C.1
-
41
-
-
0031080576
-
P53 protein expression in human multidrug-resistant CEM lymphoblasts
-
Rafki N., Liautaud-Roger F., Devy L., Trentesaux C., and Dufer J. P53 protein expression in human multidrug-resistant CEM lymphoblasts. Leuk Res 21 (1997) 147-152
-
(1997)
Leuk Res
, vol.21
, pp. 147-152
-
-
Rafki, N.1
Liautaud-Roger, F.2
Devy, L.3
Trentesaux, C.4
Dufer, J.5
-
42
-
-
0027369120
-
Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
-
Brown R., Clugston C., Burns P., Edlin A., Vasey P., Vojtesek B., et al. Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines. Int J Cancer 55 (1993) 678-684
-
(1993)
Int J Cancer
, vol.55
, pp. 678-684
-
-
Brown, R.1
Clugston, C.2
Burns, P.3
Edlin, A.4
Vasey, P.5
Vojtesek, B.6
|