Comprehensive loss of heterozygosity analysis and identification of a novel hotspot at 3p21 in salivary gland neoplasms

Otolaryngology - Head and Neck Surgery

Volumn 137, Issue 1, 2007, Pages 119-125

  Honjo, Noriyasu ^a   Gunduz, Mehmet ^a   Fukushima, Kunihiro ^a   Cengiz, Beyhan ^a   Beder, Levent B ^a   Gunduz, Esra ^a   Nagatsuka, Hitoshi ^a   Xiao, Jing ^a   Shimizu, Kenji ^a   Nishizaki, Kazunori ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACINAR CELL CARCINOMA; ADULT; AGED; ARTICLE; CHROMOSOME 10Q; CHROMOSOME 12Q; CHROMOSOME 13Q; CHROMOSOME 17P; CHROMOSOME 3P; CHROMOSOME 6Q; CHROMOSOME 8Q; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE IDENTIFICATION; GENE LOCUS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LYMPHOEPITHELIOMA; MALE; MICROSATELLITE MARKER; MYOEPITHELIOMA; PLEOMORPHIC ADENOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; SALIVARY GLAND CANCER; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE; WARTHIN TUMOR;

ADENOLYMPHOMA; ADENOMA, PLEOMORPHIC; ADULT; AGED; CARCINOMA; CARCINOMA, SQUAMOUS CELL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 6; CHROMOSOMES, HUMAN, PAIR 8; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PAROTID NEOPLASMS; SUBMANDIBULAR GLAND NEOPLASMS;

EID: 34250761905     PISSN: 01945998     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otohns.2007.01.017     Document Type: Article

References (21)

1. Beder L.B., Gunduz M., Ouchida M., et al. Genome-wide analyses on loss of heterozygosity in head and neck squamous cell carcinomas. Lab Invest 83 (2003) 99-105
2. El-Naggar A.K., Callender D., Coombes M.M., et al. Molecular genetic alterations in carcinoma ex-pleomorphic adenoma: a putative progression model?. Genes Chromosomes Cancer 27 (2000) 162-168
3. El-Naggar A.K., Hurr K., Kagan J., et al. Genotypic alterations in benign and malignant salivary gland tumors: histogenetic and clinical implications. Am J Surg Pathol 21 (1997) 691-697
4. Gillenwater A., Hurr K., Wolf P., et al. Microsatellite alterations at chromosome 8q loci in pleomorphic adenoma. Otolaryngol Head Neck Surg 117 (1997) 448-452
5. Johns III M.M., Westra W.H., Califano J.A., et al. Allelotype of salivary gland tumors. Cancer Res 56 (1996) 1151-1154
6. Rutherford S., Hampton G.M., Frierson H.F., et al. Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma. Lab Invest 85 (2005) 1076-1085
7. Sahlin P., Mark J., and Stenman G. Submicroscopic deletions of 3p sequences in pleomorphic adenomas with t(3;8)(p21;q12). Genes Chromosomes Cancer 10 (1994) 256-261
8. Gunduz M., Ouchida M., Fukushima K., et al. Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas. Cancer Res 60 (2000) 3143-3146
9. Kiss H., Kedra D., Yang Y., et al. A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3. Hum Genet 105 (1999) 552-559
10. Shriver S.P., Shriver M.D., Tirpak D.L., et al. Trinucleotide repeat length variation in the human ribosomal protein L14 gene (RPL14): localization to 3p21.3 and loss of heterozygosity in lung and oral cancers. Mutat Res 406 (1998) 9-23
11. Huang X.P., Zhao C.X., Li Q.J., et al. Alteration of RPL14 in squamous cell carcinomas and preneoplastic lesions of the esophagus. Gene 366 (2006) 161-168
12. Chano T., Kontani K., Teramoto K., et al. Truncating mutations of RB1CC1 in human breast cancer. Nat Genet 31 (2002) 285-288
13. Jandrig B., Seitz S., Hinzmann B., et al. ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2. Oncogene 23 (2004) 9295-9302
14. Kishi M., Nakamura M., Nishimine M., et al. Loss of heterozygosity on chromosome 6q correlates with decreased thrombospondin-2 expression in human salivary gland carcinomas. Cancer Sci 94 (2003) 530-535
15. Abdollahi A., Pisarcik D., Roberts D., et al. LOT1 (PLAGL1/ZAC1), the candidate tumor suppressor gene at chromosome 6q24-25, is epigenetically regulated in cancer. J Biol Chem 278 (2003) 6041-6049
16. Takahashi Y., Miyoshi Y., Takahata C., et al. Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers. Clin Cancer Res 11 (2005) 1380-1385
17. Rutherford S., Yu Y., Rumpel C.A., et al. Chromosome 6 deletion and candidate tumor suppressor genes in adenoid cystic carcinoma. Cancer Lett 236 (2006) 309-317
18. Enlund F., Persson F., and Stenman G. Molecular analyses of the candidate tumor suppressor gene, PLAGL1, in benign and malignant salivary gland tumors. Eur J Oral Sci 112 (2004) 545-547
19. Sood R., Makalowska I., Galdzicki M., et al. Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region. Genomics 82 (2003) 153-161
20. Kishi M., Nakamura M., Nishimine M., et al. Genetic and epigenetic alteration profiles for multiple genes in salivary gland carcinomas. Oral Oncol 41 (2005) 161-169
21. Fowler M.H., Fowler J., Ducatman B., et al. Malignant mixed tumors of the salivary gland: a study of loss of heterozygosity in tumor suppressor genes. Mod Pathol 19 (2006) 350-355