Chromosome 6 deletion and candidate tumor suppressor genes in adenoid cystic carcinoma

Cancer Letters

Volumn 236, Issue 2, 2006, Pages 309-317

  Rutherford, Sue ^a   Yu, Yongtao ^a   Rumpel, Craig A ^a   Frierson Jr , Henry F ^a   Moskaluk, Christopher A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Adenoid cystic carcinoma; Chromosome 6; Genetic deletion; LATS1; Loss of heterozygosity; PLAGL1

Indexed keywords

ADENOID CYSTIC CARCINOMA; ADULT; AGED; ARTICLE; CHROMOSOME 6; CHROMOSOME DELETION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE LOCUS; GENE LOSS; GENE MUTATION; GENE SEQUENCE; HETEROZYGOSITY LOSS; HISTOLOGY; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE MARKER; PRIORITY JOURNAL; SALIVARY GLAND; SALIVARY GLAND CARCINOMA; SALIVARY GLAND DUCT; TUMOR SUPPRESSOR GENE;

ADULT; AGED; CARCINOMA, ADENOID CYSTIC; CELL CYCLE PROTEINS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 6; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALIVARY DUCTS; SALIVARY GLAND NEOPLASMS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 33646494873     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.05.049     Document Type: Article

References (39)

1. Ellis G., and Auclair P. Tumors of the Salivary Glands (1996), Armed Forces Institute of Pathology, Washington, DC
2. Higashi K., Jin Y., Johansson M., Heim S., Mandahl N., Biorklund A., et al. Rearrangement of 9p13 as the primary chromosomal aberration in adenoid cystic carcinoma of the respiratory tract. Genes Chromosomes Cancer 3 (1991) 21-23
3. Hrynchak M., White V., Berean K., and Horsman D. Cytogenetic findings in seven lacrimal gland neoplasms. Cancer Genet. Cytogenet. 75 (1994) 133-138
4. Lopez-Gines C., Cerda-Nicolas M., and Llombart-Bosch A. Cytogenetic findings in a new case of adenoid cystic carcinoma arising in sphenoidal sinus. Cancer Genet. Cytogenet. 75 (1994) 150-152
5. Mark H.F., Hanna I., and Gnepp D.R. Cytogenetic analysis of salivary gland type tumors. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 82 (1996) 187-192
6. Martins C., Fonseca I., Roque L., Pinto A.E., and Soares J. Malignant salivary gland neoplasms: a cytogenetic study of 19 cases. Eur. J. Cancer B Oral Oncol. 32B (1996) 128-132
7. Nordkvist A., Mark J., Gustavsson H., Bang G., and Stenman G. Nonrandom chromosome rearrangements in adenoid cystic carcinoma of the salivary glands. Genes Chromosomes Cancer 10 (1994) 115-121
8. Roijer E., Dahlenfors R., Mark J., and Stenman G. Observations by chromosome banding, FISH and immunohistochemistry in an adenoid cystic carcinoma with del(17)(p13) as the sole deviation. Virchows Arch. 430 (1997) 339-342
9. Sandros J., Stenman G., and Mark J. Cytogenetic and molecular observations in human and experimental salivary gland tumors. Cancer Genet. Cytogenet. 44 (1990) 153-167
10. Jin C., Martins C., Jin Y., Wiegant J., Wennerberg J., Dictor M., et al. Characterization of chromosome aberrations in salivary gland tumors by FISH, including multicolor COBRA-FISH. Genes Chromosomes Cancer 30 (2001) 161-167
11. Queimado L., Reis A., Fonseca I., Martins C., Lovett M., Soares J., Parreira L., et al. A refined localization of two deleted regions in chromosome 6q associated with salivary gland carcinomas. Oncogene 16 (1998) 83-88
12. Johns M.M., Westra W.H., Califano J.A., Eisele D., Koch,D W.M., and Sidransky D. Allelotype of salivary gland tumors. Cancer Res. 56 (1996) 1151-1154
13. El-Rifai W., Rutherford S., Knuutila S., Frierson Jr. H.F., and Moskaluk C.A. Novel DNA copy number losses in chromosome 12q12-q13 in adenoid cystic carcinoma. Neoplasia 3 (2001) 173-178
14. Szanto P.A., Luna M.A., Tortoledo M.E., and White R.A. Histologic grading of adenoid cystic carcinoma of the salivary glands. Cancer 54 (1984) 1062-1069
15. AJCC Cancer Staging Manual (1997), Lippincott-Raven Publishers, Philadelphia
16. Moskaluk C., and Kern S. Microdissection and PCR amplification of genomic DNA from histologic tissue sections. Am. J. Pathol. 150 (1997) 1547-1552
17. Rumpel C.A., Powell S.M., and Moskaluk C.A. Mapping of genetic deletions on the long arm of chromosome 4 in human esophageal adenocarcinomas. Am. J. Pathol. 154 (1999) 1329-1334
18. Emmert-Buck M.R., Lubensky I.A., Dong Q., Manickam P., Guru S.C., Kester M.B., et al. Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis. Cancer Res. 57 (1997) 1855-1858
19. Godfrey T.E., Kim S.H., Chavira M., Ruff D.W., Warren R.S., Gray J.W., and Jensen R.H. Quantitative mRNA expression analysis from formalin-fixed paraffin-embedded tissue using 5′ nuclease quantitative reverse transcription-polymerase chain reaction. J. Mol. Diag. 2 (2000) 84-90
20. Moskaluk C.A., Zhang H., Powell S.M., Cerilli L.A., Hampton G.M., and Frierson Jr. F.H. Cdx2 protein expression in normal and malignant human tissues: an immunohistochemical survey using tissue microarrays. Mod. Pathol. 16 (2003) 913-919
21. Girard L., Zochbauer-Muller S., Virmani A.K., Gazdar A.F., and Minna J.D. Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering. Cancer Res. 60 (2000) 4894-4906
22. Vogelstein B., Fearon E.R., Kern S.E., Hamilton S.R., Preisinger A.C., Nakamura Y., et al. Allelotype of colorectal carcinomas. Science 244 (1989) 207-211
23. Pruitt K.D., and Maglott D.R. RefSeq and LocusLink: NCBI gene-centered resources. Nucleic Acids Res. 29 (2001) 137-140
24. Human Genome Project Working Draft, University of California at Santa Cruz.
25. Haber D., and Harlow E. Tumour-suppressor genes: evolving definitions in the genomic age. Nat. Genet. 16 (1997) 320-322
26. Jones P.A., and Laird P.W. Cancer epigenetics comes of age. Nat. Genet. 21 (1999) 163-167
27. Abdollahi A., Bao R., and Hamilton T.C. LOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger protein. Oncogene 18 (1999) 6477-6487
28. Abdollahi A., Godwin A.K., Miller P.D., Getts L.A., Schultz D.C., Taguchi T., et al. Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells. Cancer Res. 57 (1997) 2029-2034
29. Abdollahi A., Roberts D., Godwin A.K., Schultz D.C., Sonoda G., Testa J.R., et al. Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors. Oncogene 14 (1997) 1973-1979
30. Bilanges B., Varrault A., Basyuk E., Rodriguez C., Mazumdar A., Pantaloni C., et al. Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors. Oncogene 18 (1999) 3979-3988
31. Varrault A., Ciani E., Apiou F., Bilanges B., Hoffmann A., Pantaloni C., et al. hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. Proc. Natl Acad. Sci. USA 95 (1998) 8835-8840
32. Xu T., Wang W., Zhang S., Stewart R.A., and Yu W. Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121 (1995) 1053-1063
33. Yang X., Li D.M., Chen W., and Xu T. Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis. Oncogene 20 (2001) 6516-6523
34. Hisaoka M., Tanaka A., and Hashimoto H. Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma. Lab. Invest. 82 (2002) 1427-1435
35. Xia H., Qi H., Li Y., Pei J., Barton J., Blackstad M., et al. LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene 21 (2002) 1233-1241
36. Theile M., Seitz S., Arnold W., Jandrig B., Frege R., Schlag P.M., et al. A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. Oncogene 13 (1996) 677-685
37. Huang L.W., Garrett A.P., Muto M.G., Colitti C.V., Bell D.A., Welch W.R., et al. Identification of a novel 9 cM deletion unit on chromosome 6q23-24 in papillary serous carcinoma of the peritoneum. Hum. Pathol. 31 (2000) 367-373
38. Colitti C.V., Rodabaugh K.J., Welch W.R., Berkowitz R.S., and Mok S.C. A novel 4 cM minimal deletion unit on chromosome 6q25.1-q25.2 associated with high grade invasive epithelial ovarian carcinomas. Oncogene 16 (1998) 555-559
39. Noviello C., Courjal F., and Theillet C. Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: possibly four regions of deletion. Clin. Cancer Res. 2 (1996) 1601-1606