A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3

Human Genetics

Volumn 105, Issue 6, 1999, Pages 552-559

  Kiss, Hajnalka ^a   Kedra, Darek ^b   Yang, Ying ^a   Kost Alimova, Maria ^a   Kiss, Csaba ^a   O'Brien, Kevin P ^b   Fransson, Ingegerd ^b   Klein, George ^a   Imreh, Stephan ^a   Dumanski, Jan P ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CONTIG; CYSTEINE; LEUCINE TRANSFER RNA LIGASE; LIM PROTEIN; MESSENGER RNA; MITOCHONDRIAL ENZYME;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CHROMOSOME 3P; CHROMOSOME 9; CONSENSUS SEQUENCE; DEVELOPMENT; GENE LOCATION; GENE STRUCTURE; HUMAN; INTERSTITIAL CHROMOSOME DELETION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; CARRIER PROTEINS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 3; GENES, TUMOR SUPPRESSOR; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PHYSICAL CHROMOSOME MAPPING; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; SEQUENCE ALIGNMENT; TUMOR SUPPRESSOR PROTEINS;

EUKARYOTA;

EID: 18744432764     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390051144     Document Type: Article

References (35)

1. Beckerle MC (1997) Zyxin: zinc fingers at sites of cell adhesion. Bioessays 19:949-957
2. Bucher P, Bairoch A (1994) A generalized profile syntax for biomolecular sequence motifs and its function in automatic sequence interpretation. Ismb 2:53-61
3. Cheng AK, Robertson EJ (1995) The murine LIM-kinase gene (limk) encodes a novel serine threonine kinase expressed predominantly in trophoblast giant cells and the developing nervous system. Mech Dev 52:187-197
4. Crawford AW, Pino JD, Beckerle MC (1994) Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeleton. J Cell Biol 124:117-127
5. Dawid IB, Toyama R, Taira M (1995) LIM domain proteins. C R Acad Sci III 318:295-306
6. Dawid IB, Breen JJ, Toyama R (1998) LIM domains: multiple roles as adapters and functional modifiers in protein interactions. Trends Genet 14:156-162
7. Fedorova L, Kost-Alimova M, Gizatullin RZ, Alimov A, Zabarovska VI, Szeles A, Protopopov AI, Vorobieva NV, Kashuba VI, Klein G, Zelenin AV, Sheer D, Zabarovsky ER (1997) Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'-monophosphate synthetase gene to human chromosome 3. Eur J Hum Genet 5:110-116
8. Feinberg AP, Vogelstein B (1984) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity (addendum). Anal Biochem 137:266-267
9. Freyd G, Kim SK, Horvitz HR (1990) Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11. Nature 344:876-879
10. Gill GN (1995) The enigma of LIM domains. Structure 3:1285-1289
11. Imreh S, Kholodnyuk I, Allikmetts R, Stanbridge EJ, Zabarovsky ER, Klein G (1994) Nonrandom loss of human chromosome 3 fragments from mouse-human microcell hybrids following progressive growth in SCID mice. Genes Chromosomes Cancer 11:237-245
12. Imreh S, Kost-Alimova M, Kholodnyuk I, Yang Y, Szeles A, Kiss H, Liu Y, Foster K, Zabarovsky E, Stanbridge E, Klein G (1997) Differential elimination of 3p and retention of 3q segments in human/mouse microcell hybrids during tumor growth. Genes Chromosomes Cancer 20:224-233
13. Karlsson O, Thor S, Norberg T, Ohlsson H, Edlund T (1990) Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys-His domain. Nature 344:879-882
14. Kedra D, Pan HQ, Seroussi E, Fransson I, Guilbaud C, Collins JE, Dunham I, Blennow E, Roe BA, Piehl F, Dumanski JP (1998) Characterization of the human synaptogyrin gene family. Hum Genet 103:131-141
15. Kholodnyuk I, Kost-Alimova M, Kashuba V, Gizatulin R, Szeles A, Stanbridge EJ, Zabarovsky ER, Klein G, Imreh S (1997) A 3p21.3 region is preferentially eliminated from human chromosome 3/mouse microcell hybrids during tumor growth in SCID mice. Genes Chromosomes Cancer 18:200-211
16. Kok K, Naylor SL, Buys CH (1997) Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv Cancer Res 71:27-92
17. Kozak M (1996) Interpreting cDNA sequences: some insights from studies on translation. Mamm Genome 7:563-574
18. Lupas A, Van Dyke M, Stock J (1991) Predicting coiled coils from protein sequences. Science 252:1162-1164
19. Macalma T, Otte J, Hensler ME, Bockholt SM, Louis HA, Kalff-Suske M, Grzeschik KH, Ahe D von der, Beckerle MC (1996) Molecular characterization of human zyxin. J Biol Chem 271:31470-31478
20. Mitelman F, Mertens F, Johansson B (1997) A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet 15:417-74
21. Petit MMR, Mols R, Schoenmakers EF, Mandahl N, Van de Ven WJ (1996) LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics 36:118-129
22. Peyrard M, Pan HQ, Kedra D, Fransson I, Swahn S, Hartman K, Clifton SW, Roe BA, Dumanski JP (1996) Structure of the promoter and genomic organization of the human beta-adaptin gene (BAM22) from chromosome 22q12. Genomics 36:112-117
23. Ptashne M (1988) How eukaryotic transcriptional activators work. Nature 335:683-689
24. Ren R, Mayer BJ, Cicchetti P, Baltimore D (1993) Identification of a ten-amino acid proline-rich SH3 binding site. Science 259:1157-1161
25. Sadler I, Crawford AW, Michelsen JW, Beckerle MC (1992) Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton. J Cell Biol 119:1573-1587
26. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
27. Sanchez-Garcia I, Rabbitts TH (1994) The LIM domain: a new structural motif found in zinc-finger-like proteins. Trends Genet 10:315-320
28. Seroussi E, Pan HQ, Kedra D, Roe BA, Dumanski JP (1998) Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Gene 212:13-20
29. Shaw G, Kamen R (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659-667
30. Staden RE (1994) The Staden package. Humana Press, Totawa, New Jersey
31. Szeles A, Yang Y, Sandlund AM, Kholodnyuk I, Kiss H, Kost-Alimova M, Zabarovsky ER, Stanbridge E, Klein G, Imreh S (1997) Human/mouse microcell hybrid based elimination test reduces the putative tumor suppressor region at 3p21.3 to 1.6 cM. Genes Chromosomes Cancer 20:329-336
32. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG (1997) The CLUSTAL-X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882
33. Wolf E, Kim PS, Berger B (1997) MultiCoil: a program for predicting two-and three-stranded coiled coils. Protein Sci 6:1179-1189
34. Yang Y, Kiss H, Kost-Alimova M, Kedra D, Fransson I, Seroussi E, Li J, Szeles A, Kholodnyuk I, Imreh MP, Fodor K, Hadlaczky G, Klein G, Dumanski JP, Imreh S (1999) A one megabase PAC contig spanning the common eliminated region 1 (CER 1) in 3p21.3. Genomics (in press)
35. Yi J, Beckerle MC (1998) The human TRIP6 gene encodes a LIM domain protein and maps to chromosome 7q22, a region associated with tumorigenesis. Genomics 49:314-316