Aspirin can elicit the recurrence of gastric ulcer induced with acetic acid in rats

Cellular Physiology and Biochemistry

Volumn 20, Issue 1-4, 2007, Pages 205-212

  Wang, Guo Zhong ^a,b   Huang, Guo Ping ^a   Yin, Guo Li ^c   Zhou, Gang ^c   Guo, Chun Juan ^a   Xie, Chun Gang ^a   Jia, Bing Bing ^a   Wang, Jin Fu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b QIQIHAR MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Aspirin; Cyclooxygenase; Gastric ulcer; Mucosal blood flow; Ulcer healing

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MESSENGER RNA; PROSTAGLANDIN E2; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; DRUG MECHANISM; GASTRIC PH MONITORING; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECURRENT PEPTIC ULCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; STATISTICAL SIGNIFICANCE; STOMACH JUICE; STOMACH MUCOSA BLOOD FLOW; STOMACH MUCUS; STOMACH SECRETION; STOMACH ULCER; ULCER HEALING; WESTERN BLOTTING;

RATTUS;

EID: 34250740299     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000104167     Document Type: Article

References (38)

1. Villegas I, La Casa C, de la Lastra CA, Motilva V, Herrerias JM, Martin MJ: Mucosal damage induced by preferential COX-1 and COX-2 inhibitors: role of prostaglandins and inflammatory response. Life Sci 2004;74:873-884.
2. Tibble J, Sigthorsson G, Caldwell C, Palmer RH, Bjarnason I: Effects of NSAIDs on cryoprobe-induced gastric ulcer healing in rats. Aliment Pharmacol Ther 2001;15:2001-2008.
3. Hull MA, Knifton A, Filipowicz B, Brough JL, Vautier G, Hawkey CJ: Healing with basic fibroblast growth factor is associated with reduced indomethacin induced relapse in a human model of gastric ulceration. Gut 1997;40:204-210.
4. Arakawa T, Watanabe T, Fukuda T, Higuchi K, Fujiwara Y, Kobayashi K, Tarnawski A: Ulcer recurrence: cytokines and inflammatory response-dependent process. Dig Dis Sci 1998;43:61S-66S.
5. Kauffman G: Aspirin-induced gastric mucosal injury: lessons learned from animal models. Gastroenterology 1989;96:606-614.
6. Pawlik T, Konturek PC, Konturek JW, Konturek SJ, Brzozowski T, Czesnikiewicz M, Plonka M, Bielanski W, Areny H: Impact of Helicobacter pylori and nonsteroidal anti-inflammatory drugs on gastric ulcerogenesis in experimental animals and in humans. Eur J Pharmacol 2002;449:1-15.
7. Wang JY, Yamasaki S, Takeuchi K, Okabe S: Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. Gastroenterology 1989;96:393-402.
8. Penney AG, Andrews FJ, O'Brien PE: Effects of misoprostol on delayed ulcer healing induced by aspirin. Dig Dis Sci 1994;39:934-939.
9. Hirose H, Takeuchi K, Okabe S: Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. Gastroenterology 1991;100:1259-1265.
10. Wallace JL: Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract. Mechanisms of protection and healing: current knowledge and future research. Am J Med 2001;110:19S-23S.
11. Tarnawski A, Douglass TG, Stachura J, Krause WJ: Quality of gastric ulcer healing: histological and ultrastructural assessment. Aliment Pharmacol Ther 1991;5:79-90.
12. Tarnawski A, Stachura J, Krause WJ, Douglass TG, Gergely H: Quality of gastric ulcer healing: a new, emerging concept. J Clin Gastroenterol 1991;13:S42-47.
13. Tarnawski A, Hollander D, Krause WJ, Dabros W, Stachura J, Gergely H: "Healed" experimental gastric ulcers remain histologically and ultrastructurally abnormal. J Clin Gastroenterol 1990;12:S139-147.
14. Watanabe T, Higuchi K, Tominaga K, Fujiwara Y, Arakawa T: Acid regulates inflammatory response in a rat model of induction of gastric ulcer recurrence by interleukin 1β. Gut 2001;48:774-781.
15. Brzozowski T, Konturek PC, Konturek SJ, Sliwowski Z, Pajdo R, Drozdowicz D, Ptak A, Hahn EG: Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers. Microsc Res Tech 2001;53:343-353.
16. Ma L, Wang WP, Chow JY, Yuen ST, Cho CH: Reduction of EGF is associated with the delay of ulcer healing by cigarette smoking. Am J Physiol Gastrointest Liver Physiol 2000;278:G10-G17.
17. Piper DW, Whitecross D, Leonard P, Clarke A: Alcian blue binding properties of gastric juice. Gastroenterology 1970;59:534-538.
18. Brzozowski T, Konturek PC, Konturek SJ, Ernst H, Stachura J, Hahn EG: Gastric adaptation to injury by repeated doses of aspirin strengthens mucosal defence against subsequent exposure to various strong irritants in rats. Gut 1995;37:749-757.
19. Futaki N, Arai I, Hamasaka Y, Takahashi S, Higuchi S, Otomo S. Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation. J Pharm Pharmacol. 1993;45:753-755.
20. Hawkey CJ: Nonsteroidal anti-inflammatory drug gastropathy. Gastroenterology 2000;119:521-535.
21. Hawkey CJ, Naesdal J, Wilson I, Langstrom G, Swannell AJ, Peacock RA, Yeomans ND: Relative contribution of mucosal injury and Helicobacter pylori in the development of gastroduodenal lesions in patients taking non-steroidal anti- inflammatory drugs. Gut 2002;51:336-343.
22. Slomiany BL, Piotrowski J, Slomiany A: Up-regulation of gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide by aspirin but not indomethacin. J Endotoxin Res 2001;7:203-209.
23. Konturek PC, Brzozowski T, Kwiecien S, Drozdowicz D, Harsch IA, Meixner H, Stachura J, Hahn EG, Konturek SJ: Effect of Helicobacter pylori on delay in ulcer healing induced by aspirin in rats. Eur J Pharmacol 2002;451:191-202.
24. Okabe S, Amagase K: An overview of acetic acid ulcer models-the history and state of the art of peptic ulcer research. Biol Pharm Bull 2005;28:1321-1341.
25. Uchida M, Kawano O, Misaki N, Irino O: Healing process of acetic acid-induced gastric ulcer and gastric mucosal prostaglandin E generation level in rats. Jpn J Pharmacol 1989;50:366-368.
26. Warzecha Z, Dembinski A, Brzozowski T, Ceranowicz P, Pajdo R, Niemiec J, Drozdowicz D, Mitis-Musiol M, Konturek SJ: Gastroprotective effect of histamine and acid secretion on ammonia-induced gastric lesions in rats. Scand J Gastroenterol 2000;35:916-924.
27. Sarosiek J, Mizuta K, Slomiany A, Slomiany BL: Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ion, and susceptibility to pepsin. Biochem Pharmacol 1986;35:4291-4295.
28. Rainsford KD, Whitehouse MW: Biochemical gastroprotection from acute ulceration induced by aspirin and related drugs. Biochem Pharmacol 1980;29:1281-1289.
29. Menguy R, Desbaillets L: Role of inhibition of gastric mucous secretion in the phenomenon of gastric mucosal injury by indomethacin. Am J Dig Dis 1967;12:862-866.
30. Phillipson M, Henriksnas J, Holstad M, Sandler S, Holm L: Inducible nitric oxide synthase is involved in acid-induced gastric hyperemia in rats and mice. Am J Physiol Gastrointest Liver Physiol 2003;285:G154-G162.
31. Phillipson M, Atuma C, Henriksnas J, Holm L: The importance of mucus layers and bicarbonate transport in preservation of gastric juxtamucosal pH. Am J Physiol Gastrointest Liver Physiol 2002;282:G211-G219.
32. Synnerstad I, Johansson M, Nylander O, Holm L: Intraluminal acid and gastric mucosal integrity: the importance of blood-borne bicarbonate. Am J Physiol Gastrointest Liver Physiol 2001;280:G121-G129.
33. Bjorne H H, Petersson J, Phillipson M, Weitzberg E, Holm L, Lundberg JO: Nitrite in saliva increases gastric mucosal blood flow and mucus thickness. J Clin Invest 2004;113:106-114.
34. Sun WH, Tsuji S, Tsujii M, Gunawan ES, Kawai N, Kimura A, Kakiuchi Y, Yasumaru M, Iijima H, Okuda Y, Sasaki Y, Hori M, Kawano S: Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther 2000;295:447-452.
35. Halter F, Tarnawski AS, Schmassmann A, Peskar BM: Cyclooxygenase 2-implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives. Gut 2001;49:443-453.
36. Brzozowski T: Experimental production of peptic ulcer, gastric damage and cancer models and their use in pathophysiological studies and pharmacological treatment-Polish achievements. J Physiol Pharmacol 2003;54:99-126.
37. Chan FK, Leung WK: Peptic-ulcer disease. Lancet 2002;360:933-941.
38. Watanabe T, Higuchi K, Hamaguchi M, Shiba M, Tominaga K, Fujiwara Y, Matsumoto T, Arakawa T: Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha. Am J Physiol Gastrointest Liver Physiol 2004;287:G919-G928.