Role of transforming growth factor β in rat bladder smooth muscle cell proliferation

Journal of Pharmacology and Experimental Therapeutics

Volumn 322, Issue 1, 2007, Pages 117-122

  Barendrecht, Maurits M ^a   Mulders, Arthur C M ^a   Van Der Poel, Henk ^b   Van Den Hoff, Maurice J B ^a   Schmidt, Martina ^a,c   Michel, Martin C ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECEPTOR BLOCKING AGENT; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR ANTAGONIST; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLADDER DISEASE; CELL COUNT; CELL CULTURE; CELL DEATH; CELL GROWTH; CELL SIZE; CONTROLLED STUDY; DNA SYNTHESIS; FLOW CYTOMETRY; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SERUM; SMOOTH MUSCLE FIBER;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTROPHY; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; RATS; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA; URINARY BLADDER;

EID: 34250692066     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.119115     Document Type: Article

References (35)

1. Akutsu S, Shimada A, and Yamane A (2006) Transforming growth factor βs are upregulated in the rat masseter muscle hypertrophied by clenbuterol, a β2 adrenergic agonist. Br J Pharmacol 147:412-421.
2. Andersson KE (2003) Storage and voiding symptoms: pathophysiologic aspects. Urology 62 (Suppl 2):3-10.
3. Azhar M, Schultz JJ, Grupp I, Dorn GW, Meneton P, Molin DG, Gittenberger-de Groot AC, and Doetschman T (2003) Transforming growth factor beta in cardiovascular development and function. Cytokine Growth Factor Rev 14:391-407.
4. Baskin LS, Hayward SW, Sutherland RA, DiSandro MJ, Thomson AA, Goodman J, and Cunha GR (1996) Mesenchymal-epithelial interactions in the bladder. World J Urol 14:301-309.
5. 3 muscarinic receptor function in human detrusor cultured smooth muscle cells. J Urol 168:2672-2676.
6. Chen G and Khalil N (2006) TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases. Respir Res 7:2.
7. Chen MW, Krasnapolsky L, Levin RM, and Buttyan R (1994) An early molecular response induced by acute overdistension of the rabbit urinary bladder. Mol Cell Biochem 132:39-44.
8. Derynck R and Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425:577-584.
9. Ewen ME, Sluss HK, Whitehouse LL, and Livingston DM (1993) TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009-1020.
10. Feng XH and Derynck R (2005) Specificity and versatility in TGF-β signaling through Smads. Annu Rev Cell Dev Biol 21:659-693.
11. Herrmann J, Borkham-Kamphorst E, Haas U, Van de LE, Fraga MF, Esteller M, Gressner AM, and Weiskirchen R (2006) The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-β in smooth muscle and hepatic stellate cells. Biochem Biophys Res Commun 345:1526-1535.
12. Howard PS, Kucich U, Coplen DE, and He Y (2005) Transforming growth factor-beta1-induced hypertrophy and matrix expression in human bladder smooth muscle cells. Urology 66:1349-1353.
13. Kapoun AM, Gaspar NJ, Wang Y, Damm D, Liu YW, O'Young G, Quon D, Lam A, Munson K, Tran TT, et al. (2006) Transforming growth factor-β receptor type 1 (TGFβRI) kinase activity but not p38 activation is required for TGFβRI-induced myofibroblast differentiation and profibrotic gene expression. Mol Pharmacol 70: 518-531.
14. Chul Kim J, Seo SI, Park YH, and Hwang TK (2001) Changes in detrusor and urinary growth factors according to detrusor function after partial bladder outlet obstruction in the rat. Urology 57:371-375.
15. Kropp BP, Zhang Y, Tomasek JJ, Cowan R, Furness PD III, Vaughan MB, Parizi M, and Cheng EY (1999) Characterization of cultured bladder smooth muscle cells: assessment of in vitro contractility. J Urol 162:1779- 1784.
16. Lebrin F, Deckers M, Bertolino P, and Ten DP (2005) TGF-β receptor function in the endothelium. Cardiovasc Res 65:599-608.
17. Levin RM, Wein AJ, Buttyan R, Monson FC, and Longhurst PA (1994) Update on bladder smooth-muscle physiology. World J Urol 12:226-232.
18. Liu X, Sun SQ, Hassid AI, and Ostrom RS (2006) cAMP inhibits transforming growth factor-β-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts. Mol Pharmacol 70:1992-2003.
19. 3 receptors and β-adrenoceptor in cultured rat bladder smooth muscle. Life Sci 70:1159-1172.
20. 1 excretion in children with posterior urethral valves. Urology 56:311-314.
21. Malkowicz SB, Thomas J, and Levin RM (1995) The effect of cholinergic stimulation on cultured smooth muscle cells. Adv Exp Med Biol 385:257-260.
22. Massagué J (2000) How cells read TGF-β signals. Nat Rev Mol Cell Biol 1:169-178.
23. Monga M, Gabal-Shehab LL, and Stein P (2001) Urinary transforming growth factor-β1 levels correlate with bladder outlet obstruction. Int J Urol 8:487-489.
24. Ninomiya K, Takahashi A, Fujioka Y, Ishikawa Y, and Yokoyama M (2006) Transforming growth factor-β signaling enhances transdifferentiation of macrophages into smooth muscle-like cells. Hypertens Res 29:269-276.
25. 1 cell cycle arrest. J Cell Physiol 156:48-55.
26. Reynisdóttir I, Polyak K, Iavarone A, and Massague J (1995) Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 9:1831-1845.
27. Roberts AB (1998) Molecular and cell biology of TGF-β. Miner Electrolyte Metab 24:111-119.
28. Roberts AB and Sporn MB (1993) Physiological actions and clinical applications of transforming growth factor-β (TGF-β). Growth Factors 8:1-9.
29. Seay U, Sedding D, Krick S, Hecker M, Seeger W, and Eickelberg O (2005) Transforming growth factor-β-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther 315:1005-1012.
30. Sharif-Afshar AR, Donohoe JM, Pope JC, Adams MC, Brock JW III and Bhowmick NA (2005) Stromal hyperplasia in male bladders upon loss of transforming growth factor-β signaling in fibroblasts. J Urol 174:1704-1707.
31. Sterle M, Kreft ME, and Batista U (1997) The effect of epidermal growth factor and transforming growth factor β1 on proliferation and differentiation of urothelial cells in urinary bladder explant culture. Biol Cell 89:263-271.
32. van der Poel HG (2005) Androgen receptor and TGFbeta1/Smad signaling are mutually inhibitory in prostate cancer. Eur Urol 48:1051-1058.
33. Watkins SJ, Jonker L, and Arthur HM (2006) A direct interaction between TGFβ activated kinase 1 and the TGFβ type II receptor: implications for TGFβ signalling and cardiac hypertrophy. Cardiovasc Res 69:432-439.
34. Widmann C, Gibson S, Jarpe MB, and Johnson GL (1999) Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 79:143-180.
35. Wiesmann A, Kim M, Georgelas A, Searles AE, Cooper DD, Green WF, and Spangrude GJ (2000) Modulation of hematopoietic stem/progenitor cell engraftment by transforming growth factor β. Exp Hematol 28:128-139.