Could the effect of modeled microgravity on osteogenic differentiation of human mesenchymal stem cells be reversed by regulation of signaling pathways?

Biological Chemistry

Volumn 388, Issue 7, 2007, Pages 755-763

  Zheng, Qiang ^a,b   Huang, Guoping ^a   Yang, Jinfeng ^a   Xu, Yulin ^a   Guo, Chunjuan ^a   Xi, Yongmei ^a   Pan, Zhijun ^b   Wang, Jinfu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Adipogenesis; Human mesenchymal stem cells; Microgravity; Osteogenesis; Signaling pathways

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; TRANSCRIPTION FACTOR RUNX2;

ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MARKER GENE; MESENCHYMAL STEM CELL; MICROGRAVITY; MOLECULAR MODEL; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ALKALINE PHOSPHATASE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; MESENCHYMAL STEM CELLS; MODELS, BIOLOGICAL; OSTEOGENESIS; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; WEIGHTLESSNESS;

EID: 34250688670     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2007.082     Document Type: Article

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