The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates

Journal of Pediatrics

Volumn 132, Issue 4, 1998, Pages 731-734

  George, T N ^a   Johnson, K J ^a   Bates, J N ^a   Segar, J L ^a  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; COLLAGEN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; NITRIC OXIDE;

ARTICLE; BLEEDING TIME; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GESTATIONAL AGE; HEMATOCRIT; HUMAN; MECONIUM ASPIRATION; NEWBORN; PNEUMONIA; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RESPIRATORY DISTRESS SYNDROME; THROMBOCYTE AGGREGATION;

EID: 0031925241     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3476(98)70370-1     Document Type: Article

References (12)

1. The Neonatal Inhaled Nitric Oxide Study Group Inhaled nitric oxide in full term and nearly full-term infants with hypoxic respiratory failure N Engl J Med 336 1997 597 604
2. JD Roberts Jr JR Fineman FC Morin III PW Shaul S Rimar MD Schreiber Inhaled nitric oxide and persistent pulmonary hypertension of the newborn N Engl J Med 336 1997 605 610
3. JW Skimming KA Bender AA Hutchison WH Drummond Nitric oxide inhalation in infants with respiratory distress syndrome J Pediatr 130 1997 225 230
4. S Abman JP Kinsella MS Schaffer RB Wilkening Inhaled nitric oxide in the management of a premature infant with severe respiratory distress and pulmonary hypertension Pediatrics 92 1993 606 609
5. AF Varela A Runge LJ Ignano G Chandhuri Nitric oxide and prostacyclin inhibit fetal platelet aggregation: a response similar to that observed in adults Am J Obstet Gynecol 167 1992 1599 1604
6. E Bassenge Antiplatelet effects of endothelium-derived relaxing factor and nitric oxide donors Eur Heart J 12 Suppl E 1991 12 15
7. M Hogman C Frostell H Arnberg G Hedenstierna Bleeding time prolongation and NO inhalation Lancet 341 1993 1664 1665
8. MJ Stuart R McKenna Diseases of coagulation: the platelet and vasculature DG Nathan FA Oski Hematology of infancy and childhood 1980 WB Saunders Co Philadelphia 1234 1338
9. M Andrew V Castle L Mitchell B Paes Evaluation of an automated bleeding time device in the newborn Am J Hematol 35 1990 275 277
10. BT Mellion L Ignarro E Ohlstein E Pontecorvo A Hyman P Kadowitz Evidence for the inhibitory role of guanosine 3’,5’-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators Blood 57 1989 946 955
11. M Radomski R Palmer S Moncada Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets Br J Pharmacol 92 1987 181 187
12. SN Harris CS Rinder HM Rinder JB Tracey BR Smith R Hines Nitroprusside inhibition of platelet function is transient and reversible by catecholamine priming Anesthesiology 83 1995 1145 1152