Inhaled nitric oxide in premature neonates with severe hypoxaemic respiratory failure: A randomised controlled trial

Lancet

Volumn 354, Issue 9184, 1999, Pages 1061-1065

  Kinsella, John P ^a,k   Walsh, William F ^b   Bose, Carl L ^c   Gerstmann, Dale R ^d   Labella, J J ^e   Sardesai, Smeeta ^f   Walsh Sukys, Michele C ^g   McCaffrey, Martin J ^h   Cornfield, David N ⁱ   Bhutani, Vinod K ^j   Cutter, Gary R ^a   Baier, Monika ^a   Abman, Steven H ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UTAH VALLEY REGIONAL MEDICAL CENTER   (United States)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g CASE WESTERN RESERVE UNIVERSITY   (United States)

^h NAVAL MEDICAL CENTER SAN DIEGO   (United States)

ⁱ UNIVERSITY OF MINNESOTA   (United States)

^j PENNSYLVANIA HOSPITAL   (United States)

^k CHILDREN S HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ARTICLE; BRAIN HEMORRHAGE; CAUSE OF DEATH; CHRONIC LUNG DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; HUMAN; HYPOXEMIA; INHALATIONAL DRUG ADMINISTRATION; LUNG HEMORRHAGE; MAJOR CLINICAL STUDY; NEWBORN; PREMATURITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FAILURE;

EID: 0033604133     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)03558-8     Document Type: Article

References (30)

1. Roberts J.D., Polaner D.M., Lang P.et al. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet. 340:1992;818-819.
2. Kinsella J.P., Neish S.R., Shaffer E., Abman S.H. Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn. Lancet. 340:1992;819-820.
3. Kinsella J.P., Truog W.E., Walsh W.F.et al. Randomized, multicentre trial of inhaled nitric oxide and high frequency oscillatory ventilation in severe persistent pulmonary hypertension of the newborn. J Pediatr. 131:1997;55-62.
4. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. N Engl J Med. 336:1997;597-604.
5. Roberts J.D., Fineman J.R., Morin F.C.et al. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. N Engl J Med. 336:1997;605-610.
6. Kinsella J.P., Abman S.H. Inhaled nitric oxide in the premature neonate: animal models and clinical experience. Semin Perinatol. 21:1997;418-425.
7. Hardart G.E., Fackler J.C. Predictors of intracranial hemorrhage during neonatal extracorporeal membrane oxygenation. J Pediatr. 134:1999;156-159.
8. Kinsella J.P., Ivy D.D., Abman S.H. Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation. Am J Physiol. 267:1994;1955-1961.
9. Kinsella J.P., Ivy D.D., Abman S.H. Inhaled nitric oxide lowers pulmonary vascular resistance and improves gas exchange in severe experimental hyaline membrane disease. Pediatr Res. 36:1994;402-408.
10. Kinsella J.P., Parker T.A., Galan H.et al. Effects of inhaled nitric oxide on pulmonary edema and lung neutrophil accumulation in severe experimental hyaline membrane disease. Pediatr Res. 41:1997;457-463.
11. Abman S.H., Kinsella J.P., Schaffer M.S., Wilkening R.B. Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension. Pediatrics. 92:1993;606-609.
12. Peliowski A., Finer N.N., Etches P.C., Tierney A.J., Ryan C.A. Inhaled nitric oxide for premature infants after prolonged rupture of the membranes. J Pediatr. 126:1995;450-453.
13. Skimming J.W., Bender K.A., Hutchison A.A., Drummond W.H. Nitric oxide inhalation in infants with respiratory failure. J Pediatr. 130:1997;225-230.
14. Subhedar N.V., Shaw N.J. Changes in oxygenation and pulmonary haemodynamics in preterm infants treated with inhaled nitric oxide. Arch Dis Child. 77:1997;191-197.
15. Hogman M., Frostell C., Arnberg H., Hedenstierna G. Bleeding time prolongation and NO inhalation. Lancet. 341:1993;1664-1665.
16. Simon D.I., Stamler J.S., Jaraki O.et al. Antiplatelet properties of protein S-nitrosothiols derived from nitric oxide and endothelium-derived relaxing factor. Arterioscler Thromb. 13:1993;791-799.
17. George T.N., Johnson K.J., Bates J.N., Segar J.L. The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates. J Pediatr. 132:1998;731-734.
18. Van Meurs K.P., Rhine W.D., Asselin J.M., Durand D.J. Response of premature infants with severe respiratory to inhaled nitric oxide. Pediatr Pulmonol. 24:1997;319-323.
19. Cheung P., Peliowski A., Robertson C.M.T. The outcome of very low birth weight neonates (≤1500 g) rescued by inhaled nitric oxide: neurodevelopment in early childhood. J Pediatr. 133:1998;735-739.
20. The relationship of intraventricular hemorrhage or death with the level of umbilical artery catheter placement: a multicenter randomized clinical trial. Pediatrics. 90:1992;881-887.
21. Papile L., Burstein J., Burstein R., Koffler H. Incidence and evaluation of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1500 g. J Pediatr. 92:1978;529-534.
22. Partridge J.C., Babcock D.S., Steichen J.J.et al. Optimal timing for diagnostic cranial ultrasound in low-birth-weight infants; detection of intracranial hemorrhage and ventricular dilation. J Pediatr. 102:1983;281.
23. Subhedar N.V., Ryan S.W., Shaw N.J. Open randomised controlled trial of inhaled nitric oxide and early dexamethasone in high risk preterm infants. Arch Dis Child. 77:1997;185-190.
24. Kanwar S., Kubes P. Nitric oxide is an antiadhesive molecule for leukocytes. New Horiz. 3:1995;93-104.
25. Merritt T.A., Cochrane C.G., Holcomb K., bohl B., Hallman M., Strayer D., Edwards D.K. Elastase and α-1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. J Clin Invest. 72:1983;656-666.
26. Ogden B.E., Murphy S., Saunders G.C., Johnson J.D. Lung lavage of newborns with respiratory distress syndrome: prolonged neutrophil influx is associated with bronchopulmonary dysplasia. Chest. 83:1983;31-33.
27. Speer C.P., Ruess D., Harms K., Herting E., Gefeller O. Neutrophil elastase and acute pulmonary damage in neonates with severe respiratory distress syndrome. Pediatrics. 91:1993;794-799.
28. Brus F., Van Oeveren W., Heikamp A., Okken A., Oetomo S.B. Leakage of protein into lungs of preterm ventilated rabbits is correlated with activation of clotting, complement, and polymorphonuclear leukocytes in plasma. Pediatr Res. 39:1996;958-965.
29. Zimmerman J.J. Bronchoalveolar inflammatory pathophysiology of bronchopulmonary dysplasia. Clin Perinatol. 22:1995;429-456.
30. Sugiura M., McCulloch P.R., Wren S., Dawson R.H., Froese A.B. Ventilator pattern influences neutrophil influx and activation in atelactasis-prone rabbit lung. J Appl Physiol. 77:1994;1355-1365.