Different dark conformations function in color-sensitive photosignaling by the sensory rhodopsin I-HtrI complex

Biophysical Journal

Volumn 92, Issue 11, 2007, Pages 4045-4053

  Sasaki, Jun ^a   Phillips, Brian J ^a   Chen, Xinpu ^a   Van Eps, Ned ^b   Tsai, Ah Lim ^a   Hubbell, Wayne L ^b   Spudich, John L ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEA KINASE; CYSTEINE; SENSORY RHODOPSIN; SERINE;

ARTICLE; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; ENZYME INHIBITION; MUTATION; PHOTON; WILD TYPE;

EID: 34250370543     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.101121     Document Type: Article

References (30)

1. Spudich, J. L., and R. A. Bogomolni. 1984. Mechanism of colour discrimination by a bacterial sensory rhodopsin. Nature. 312:509-513.
2. Yao, V. J., and J. L. Spudich. 1992. Primary structure of an archaebacterial transducer, a methyl-accepting protein associated with sensory rhodopsin I. Proc. Natl. Acad. Sci. USA. 89:11915-11919.
3. Swartz, T. E., I. Szundi, J. L. Spudich, and R. A. Bogomolni. 2000. New photointermediates in the two photon signaling pathway of sensory rhodopsin-I. Biochemistry. 39:15101-15109.
4. Lutz, I., A. Sieg, A. A. Wegener, M. Engelhard, I. Boche, M. Otsuka, D. Oesterhelt, J. Wachtveitl, and W. Zinth. 2001. Primary reactions of sensory rhodopsins. Proc. Natl. Acad. Sci. USA. 98:962-967.
5. Hoff, W. D., K.-H. Jung, and J. L. Spudich. 1997. Molecular mechanism of photosignaling by archaeal sensory rhodopsins. Annu. Rev. Biophys. Biomol. Struct. 26:223-258.
6. Jung, K.-H., and J. L. Spudich. 1998. Suppressor mutation analysis of the sensory rhodopsin I-transducer complex: insights into the color-sensing mechanism. J. Bacteriol. 180:2033-2042.
7. Kataoka, M., H. Kamikubo, F. Tokunaga, L. S. Brown, Y. Yamazaki, A. Maeda, M. Sheves, R. Needleman, and J. K. Lanyi. 1994. Energy coupling in an ion pump. The reprotonation switch of bacteriorhodopsin. J. Mol. Biol. 243:621-638.
8. Spudich, J. L., and J. K. Lanyi. 1996. Shuttling between two protein conformations: the common mechanism for sensory transduction and ion transport. Curr. Opin. Cell Biol. 8:452-457.
9. 73 intrahelical salt bridge. Proc. Natl. Acad. Sci. USA. 94:4960-4965.
10. Bogomolni, R. A., W. Stoekenius, I. Szundi, E. Perozo, K. D. Olson, and J. L. Spudich. 1994. Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I. Proc. Natl. Acad. Sci. USA. 91:10188-10192.
11. Olson, K. D., X.-N. Zhang, and J. L. Spudich. 1995. Residue replacements of buried aspartyl and related residues in sensory rhodopsin I: D201N produces inverted phototaxis signals. Proc. Natl. Acad. Sci. USA. 92:3185-3189.
12. Chen, X., and J. L. Spudich. 2002. Demonstration of 2:2 stoichiometry in the functional SRI-HtrI signaling complex in Halobacterium membranes by gene fusion analysis. Biochemistry. 41:3891-3896.
13. Chen, B., and A. E. Przybyla. 1994. An efficient site-directed mutagenesis method based on PCR. Biotechniques. 17:657-659.
14. Yan, B., and J. L. Spudich. 1991. Evidence that the repellent receptor form of sensory rhodopsin I is an attractant signaling state. Photochem. Photobiol. 54:1023-1026.
15. Spudich, E. N., and J. L. Spudich. 1993. The photochemical reactions of sensory rhodopsin I are altered by its transducer. J. Biol. Chem. 268:16095-16097.
16. Yao, V. J., E. N. Spudich, and J. L. Spudich. 1994. Identification of distinct domains for signaling and receptor interaction of the sensory rhodopsin I transducer, HtrI. J. Bacteriol. 176:6931-6935.
17. Zhang, X.-N., J. Zhu, and J. L. Spudich. 1999. The specificity of interaction of archaeal transducers with their cognate sensory rhodopsins is determined by their transmembrane helices. Proc. Natl. Acad. Sci. USA. 96:857-862.
18. Chen, X., and J. L. Spudich. 2004. Five residues in the HtrI transducer membrane-proximal domain close the cytoplasmic proton-conducting channel of sensory rhodopsin I. J. Biol. Chem. 279:42964-42969.
19. Yang, C. S., O. Sineshchekov, E. N. Spudich, and J. L. Spudich. 2004. The cytoplasmic membrane-proximal domain of the HtrII transducer interacts with the E-F loop of photoactivated Natronomonas pharaonis sensory rhodopsin II. J. Biol. Chem. 279:42970-42976.
20. Rudolph, J., and D. Oesterhelt. 1995. Chemotaxis and phototaxis require a CheA histidine kinase in the archaeon Halobacterium salinarium. EMBO J. 14:667-673.
21. Subramaniam, S., M. Gerstein, D. Oesterhelt, and R. Henderson. 1993. Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin. EMBO J. 12:1-8.
22. Subramaniam, S., and R. Henderson. 2000. Molecular mechanism of vectorial proton translocation by bacteriorhodopsin. Nature. 406:653-657.
23. Steinhoff, H. J., R. Mollaaghababa, C. Altenbach, K. Hideg, M. Krebs, H. G. Khorana, and W. L. Hubbell. 1994. Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. Science. 266:105-107.
24. Vonck, J. 1996. A three-dimensional difference map of the N intermediate in the bacteriorhodopsin photocycle: part of the F helix tilts in the M to N transition. Biochemistry. 35:5870-5878.
25. Xiao, W., L. S. Brown, R. Needleman, J. K. Lanyi, and Y. K. Shin. 2000. Light-induced rotation of a transmembrane alpha-helix in bacteriorhodopsin. J. Mol. Biol. 304:715-721.
26. Wegener, A. A., I. Chizhov, M. Engelhard, and H. J. Steinhoff. 2000. Time-resolved detection of transient movement of helix F in spin-labelled pharaonis sensory rhodopsin II. J. Mol. Biol. 301:881-891.
27. Wegener, A. A., J. P. Klare, M. Engelhard, and H. J. Steinhoff. 2001. Structural insights into the early steps of receptor-transducer signal transfer in archaeal phototaxis. EMBO J. 20:5312-5319.
28. Luecke, H., B. Schobert, J. K. Lanyi, E. N. Spudich, and J. L. Spudich. 2001. Crystal structure of sensory rhodopsin II at 2.4 A: insights into color tuning and transducer interaction. Science. 293:1499-1503.
29. Gordeliy, V. I., J. Labahn, R. Moukhametzianov, R. Efremov, J. Granzin, R. Schlesinger, G. Buldt, T. Savopol, A. J. Scheidig, J. P. Klare, and M. Engelhard. 2002. Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex. Nature. 419:484-487.
30. Bordignon, E., J. P. Klare, M. Doebber, A. A. Wegener, S. Martell, M. Engelhard, and H. J. Steinhoff. 2005. Structural analysis of a HAMP domain: the linker region of the phototransducer in complex with sensory rhodopsin II. J. Biol. Chem. 280:38767-38775.