Light-induced rotation of a transmembrane α-helix in bacteriorhodopsin

Journal of Molecular Biology

Volumn 304, Issue 5, 2000, Pages 715-721

  Xiao, Wenzhong ^a   Brown, Leonid S ^b   Needleman, Richard ^c   Lanyi, Janos K ^b   Shin, Yeon Kyun ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d IOWA STATE UNIVERSITY   (United States)

Author keywords

Bacteriorhodopsin; Conformational change; EPR spectroscopy; Transmembrane

Indexed keywords

BACTERIORHODOPSIN; CYSTEINE; MEMBRANE PROTEIN; MUTANT PROTEIN; NITROXIDE; SCHIFF BASE;

ALPHA HELIX; ARTICLE; CATTLE; CHIRALITY; CONFORMATIONAL TRANSITION; ELECTRON SPIN RESONANCE; GENETIC ENGINEERING; ISOMER; LIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTON TRANSPORT; RETINA; SPIN LABELING;

EID: 0034671339     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4255     Document Type: Article

References (39)

1. Functions of a new photoreceptor membrane
2. Structure and function of G protein-coupled receptors
3. Protein-protein interaction converts a proton pump into a sensory receptor
4. Bacteriorhodopsin as a model for proton pumps
5. Model systems for the study of seven-transmembrane-segment receptors
6. G-protein-coupled receptors: Molecular mechanisms involved in receptor activation and selectivity of G-protein recognition
7. Electron crystallographic refinement of the structure of bacteriorhodopsin
8. Surface of bacteriorhodopsin revealed by high-resolution electron crystallography
9. Protein, lipid and water organization in bacteriorhodopsin crystals: A molecular view of the purple membrane at 1.9 Angstrom resolution
10. Structure of bacteriorhodopsin at 1.55 angstrom resolution
11. X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles
12. Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin
13. Structure of the N intermediate of bacteriorhodopsin revealed by X-ray diffraction
14. Protein conformational changes in the bacteriorhodopsin photocycle
15. Structure of the bacteriorhodopsin mutant F219L N intermediate revealed by electron crystallography
16. Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution
17. Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin
18. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
19. Arrangement of rhodopsin transmembrane alpha-helices
20. Investigation of structure and dynamics in membrane proteins using site-directed spin labeling
21. Recent advances in site-directed spin labeling of proteins
22. Identification of protein folding patterns using site-directed spin labeling. Structural characterization of a beta-sheet and putative substrate binding regions in the conserved domain of alpha A-crystallin
23. +-channel activation gating
24. The synaptic SNARE complex is a parallel four-stranded helical bundle
25. Determination of the distance between two spin labels attached to a macromolecule
26. Nitroxide spin-spin interactions: Applications to protein structure and dynamics
27. EPR spectroscopic ruler: The method and its applications
28. Transient channel-opening in bacteriorhodopsin: An EPR study
29. Direct measurement of small ligand-induced conformational changes in the aspartate chemoreceptor using EPR
30. A piston model for transmembrane signaling of the aspartate receptor
31. Closing in on bacteriorhodopsin: Progress in understanding the molecule
32. Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin
33. Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: Loop-specific conformational changes in M
34. Conformational change of helix G in the bacteriorhodopsin photocycle: Investigation with heavy atom labeling and X-ray diffraction
35. Proteins in motion
36. Molecular mechanism of vectorial proton translocation by bacteriorhodopsin
37. An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium
38. Functional significance of a protein conformation change at the cytoplasmic end of helix F during the bacteriorhodopsin photocycle
39. Connectivity of the retinal Schiff base to Asp85 and Asp96 during the bacteriorhodopsin photocycle: The local-access model