Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis

Laboratory Investigation

Volumn 87, Issue 7, 2007, Pages 651-661

  Cheung, Caroline T Y ^a   Deisher, Theresa A ^b   Luo, Honglin ^a   Yanagawa, Bobby ^a   Bonigut, Stefanie ^b   Samra, Amrit ^a   Zhao, Hongyan ^a   Walker, Elizabeth K ^a   McManus, Bruce M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b AMGEN INC   (United States)

Author keywords

4 1BB; Antibody treatment; CVB3; Echocardiography

Indexed keywords

CD137 LIGAND ANTIBODY; COLLAGEN; GELATINASE A; GELATINASE B; MACROPHAGE ELASTASE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B; DRUG EFFECT; ELECTROCARDIOGRAM; FEMALE; HEART FUNCTION; HEART INJURY; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE SIZE; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RANDOMIZATION; SCORING SYSTEM; TREATMENT OUTCOME; VIRUS MYOCARDITIS;

4-1BB LIGAND; ANIMALS; ANTIBODIES, MONOCLONAL; CARDIAC VOLUME; CARDIOMYOPATHY, DILATED; CELL LINE; COXSACKIEVIRUS INFECTIONS; DIASTOLE; HEART VENTRICLES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED STRAINS; MYOCARDITIS; MYOCARDIUM; PILOT PROJECTS; SYSTOLE; VENTRICULAR REMODELING;

EID: 34250350475     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700563     Document Type: Article

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