4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells

Cellular Immunology

Volumn 238, Issue 2, 2005, Pages 76-86

  Kim, Young H ^a   Seo, Su K ^a   Choi, Beom K ^a   Kang, Woo J ^a   Kim, Chang H ^a   Lee, Sun K ^a   Kwon, Byoung S ^a,b  

^a University of Ulsan   (South Korea)

^b LSU EYE CENTER   (United States)

Author keywords

4 1BB; CD11c+ CD8+ T cell; CD8+ T cell; Costimulation; HSV 1

Indexed keywords

CD137 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN P 15095; INHIBITOR OF APOPTOSIS PROTEIN; MONOCLONAL ANTIBODY 3H3; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ANTIVIRAL ACTIVITY; ARTICLE; CD11C+ CD8+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXICITY; EXPERIMENTAL INFECTION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IMMUNE RESPONSE; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MEDIATOR; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS CELL INTERACTION; VIRUS IMMUNITY; VIRUS INFECTION;

4-1BB LIGAND; ANIMALS; ANTIBODIES; ANTIGENS, CD11C; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNOLOGIC MEMORY; LYMPHOCYTE COUNT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TUMOR NECROSIS FACTORS; VIRUS LATENCY;

HUMAN HERPESVIRUS 1;

EID: 33646026455     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2006.01.004     Document Type: Article

References (24)

1. + T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation. J. Immunol. 172 (2004) 392-397
2. Mueller S.N., Jones C.M., Smith C.M., Heath W.R., and Carbone F.R. Rapid cytotoxic T lymphocyte activation occurs in the draining lymph nodes after cutaneous herpes simplex virus infection as a result of early antigen presentation and not the presence of virus. J. Exp. Med. 195 (2002) 651-656
3. Whitley R.J. Herpes simplex viruses. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Virology (1996), Lippincott-Raven Publishers, Philadelphia 2297
4. Zinkernagel R.M. In Fundamental Immunology. In: Paul W.E. (Ed). Immunity to Viruses. third ed. (1993), Raven Press, New York 1211
5. Smith P.M., Wolcott R.M., Chervenak R., and Jennings S.R. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-γ (IFN-γ). Virology 202 (1994) 76-88
6. + T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system. J. Gen. Virol. 68 (1987) 825-833
7. Simmons A., and Tscharke D.C. Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons. J. Exp. Med. 175 (1992) 1337-1344
8. Vinay D.S., and Kwon B.S. Role of 4-1BB in immune responses. Semin. Immunol. 10 (1998) 6481-6489
9. Melero I., Johnston J.V., Shufford W.W., Mittler R.S., and Chen L. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol. 190 (1998) 167-172
10. Kwon B., Moon C.H., Kang S., Seo S.K., and Kwon B.S. 4-1BB: still in the midst of darkness. Mol. Cell 30 (2000) 19-26
11. L and Bfl-1. J. Immunol. 169 (2002) 4882-4888
12. Miller R.E., Jones J., Le T., Whitmore J., Boiani N., Gliniak B., and Lynch D.H. 4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner. J. Immunol. 169 (2002) 1792-1800
13. Ye Z., Hellstrom I., Hayden-Ledbetter M., Dahlin A., Ledbetter J.A., and Hellstrom K.E. Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB. Nat. Med. 8 (2002) 343-348
14. Wilcox R.A., Flies D.B., Zhu G., Johnson A.J., Tamada K., Chapoval A.I., Strome S.E., Pease L.R., and Chen L. Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. J. Clin. Invest. 109 (2002) 651-659
15. Kwon B.S., Hurtado J.C., Lee Z.H., Kwack K.B., Seo S.K., Choi B.K., Koller B.H., Wolisi G., Broxmeyer H.E., and Vinay D.S. Immune responses in 4-1BB (CD137)-deficient mice. J. Immunol. 168 (2002) 5483-5490
16. + T cell responses. Nat. Immunol. 3 (2002) 536-541
17. Coles R.M., Mueller S.N., Heath W.R., Carbone F.R., and Brooks A.G. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J. Immunol. 168 (2002) 834-838
18. + T cells following an acute virus infection. Eur. J. Immunol. 33 (2003) 2736-2743
19. + T cells in vivo. J. Immunol. 154 (1995) 5684-5693
20. Kim S.K., Schluns K.S., and Lefrancois L. Induction and visualization of mucosal memory CD8 T cells following systemic virus infection. J. Immunol. 163 (1999) 4125-4132
21. + cytotoxic T cell activation and memory in virus infection. J. Immunol. 149 (1992) 1326-1333
22. + T cells and memory cells. Int. Immunol. 13 (2001) 593-600
23. + T cells facilitates homing to inflammatory sites. J. Immunol. 153 (1994) 2021-2028
24. Guidotti L.G., Ando K., Hobbs M.V., Ishikawa T., Runkel L., Schreiber R.D., and Chisari F.V. Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice. Proc. Natl. Acad. Sci. USA 91 (1994) 3764-3768