High preoperative recipient plasma 7β-hydroxycholesterol is associated with initial poor graft function after liver transplantation

Liver Transplantation

Volumn 11, Issue 12, 2005, Pages 1494-1504

  Corradini, Stefano Ginanni ^a   Micheletta, Fausta ^a   Natoli, Silvia ^a   Iappelli, Massimo ^a   Di Angelantonio, Emanuele ^a   De Marco, Rosanna ^a   Elisei, Walter ^a   Siciliano, Maria ^a   Rossi, Massimo ^a   Berloco, Pasquale ^a   Attili, Adolfo Francesco ^a   Diczfalusy, Ulf ^b   Iuliano, Luigi ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

7 OXOCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT DYSFUNCTION; GRAFT FAILURE; HUMAN; HUMAN TISSUE; LIVER CIRRHOSIS; LIVER FAILURE; LIVER ISCHEMIA; LIVER TRANSPLANTATION; MALE; OXIDATIVE STRESS; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; REPERFUSION INJURY; SCORING SYSTEM;

BIOLOGICAL MARKERS; DELAYED GRAFT FUNCTION; FOLLOW-UP STUDIES; HUMANS; HYDROXYCHOLESTEROLS; KETOCHOLESTEROLS; LIVER CIRRHOSIS; LIVER FAILURE; LIVER TRANSPLANTATION; MASS SPECTROMETRY; MIDDLE AGED; OXIDATIVE STRESS; PREOPERATIVE CARE; PROGNOSIS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 30444449036     PISSN: 15276465     EISSN: None     Source Type: Journal    
DOI: 10.1002/lt.20524     Document Type: Article

References (46)

1. Busuttil RW, Tanaka K. The utility of marginal donors in liver transplantation. Liver Transpl 2003;651-653.
2. Ginanni Corradini S, Elisei W, De Marco R, Siciliano M, Iappelli M, Pugliese F,et al. Preharvest donor hyperoxia predicts good early graft function and longer graft survival after liver transplantation. Liver Transpl 2005;11:140-151.
3. Northup PG, Berg CL. Preoperative delta-MELD score does not independently predict mortality after liver transplantation. Am J Transplant 2004;4:1643-1649.
4. Selzner N, Rudiger H, Graf R, Clavien PA. Protective strategies against ischemic injury of the liver. Gastroenterology 2003;125: 917-936.
5. Omar R, Nomikos I, Piccorelli G, Savino J, Agarwal N. Prevention of postischaemic lipid peroxidation and liver cell injury by iron chelation. Gut 1989;30:510-514.
6. Mizunuma K, Ohdan H, Tashiro H, Fudaba Y, Ito H, Asahara T. Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor. Transplantation 2003;75:579-586.
7. Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Mol Aspects Med 2000;21:49-98.
8. Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol 2001;35:297-306.
9. Jaeschke H. Reactive oxygen and mechanisms of inflammatory liver injury. J Gastroenterol Hepatol 2000;15:718-724.
10. Tsukamoto H, Rippe R, Niemela O, Lin M. Roles of oxidative stress in activation of Kupffer and Ito cells in liver fibrogenesis. J Gastroenterol Hepatol 1995;10:S50-S53.
11. Arteel GE. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003;124:778-790.
12. Loguercio C, Federico A. Oxidative stress in viral and alcoholic hepatitis. Free Radic Biol Med 2003;34:1-10.
13. Namikawa C, Shu-Ping Z, Vyselaar JR, Nozaki Y, Nemoto Y, Ono M, et al. Polymorphisms of microsomal triglyceride transfer protein gene and manganese superoxide dismutase gene in nonalcoholic steatohepatitis. J Hepatol 2004;40:781-786.
14. Aboutwerat A, Pemberton PW, Smith A, Burrows PC, McMahon RF, Jain SK, et al. Oxidant stress is a significant feature of primary biliary cirrhosis. Biochim Biophys Acta 2003;1637:142-150.
15. Bataller R, Brenner DA. Liver fibrosis. J Clin Invest 2005;115: 209-218.
16. Jain SK, Pemberton PW, Smith A, McMahon RF, Burrows PC, Aboutwerat A, et al. Oxidative stress in chronic hepatitis C: not just a feature of late stage disease. J Hepatol 2002;36:805-811.
17. Higueras V, Raya A, Rodrigo JM, Serra MA, Roma J, Romero FJ. Interferon decreases serum lipid peroxidation products of hepatitis C patients. Free Radic Biol Med 1994;16:131-133.
18. Ferre N, Camps J, Prats E, Girona J, Gomez F, Heras M, et al. Impaired vitamin E status in patients with parenchymal liver cirrhosis: relationships with lipoprotein compositional alterations, nutritional factors, and oxidative susceptibility of plasma. Metabolism 2002;51:609-615.
19. Nagita A, Ando M. Assessment of hepatic vitamin E status in adult patients with liver disease. Hepatology 1997;26:392-397.
20. Boya P, de la Pena A, Beloqui O, Larrea E, Conchillo M, Castelruiz Y, et al. Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C. J Hepatol 1999;31:808-814.
21. Yadav D, Hertan HI, Schweitzer P, Norkus EP, Pitchumoni CS. Serum and liver micronutrient antioxidants and serum oxidative stress in patients with chronic hepatitis C. Am J Gastroenterol 2002;97:2634-2639.
22. Pratico D, Iuliano L, Basili S, Ferro D, Camastra C, Cordova C, et al. Enhanced lipid peroxidation in hepatic cirrhosis. J Invest Med 1998;46:51-57.
23. Meagher EA, Barry OP, Burke A, Lucey MR, Lawson JA, Rokach J, et al. Alcohol-induced generation of lipid peroxidation products in humans. J Clin Invest 1999;104:805-813.
24. Biasi F, Bosco M, Chiappino I, Chiarpotto E, Lanfranco G, Ottobrelli A, et al. Oxidative damage in human liver transplantation. Free Radic Biol Med 1995;19:311-317.
25. Burke A, FitzGerald GA, Lucey MR. A prospective analysis of oxidative stress and liver transplantation. Transplantation 2002; 74:217-221.
26. Micheletta F, Natoli S, Misuraca M, Sbarigia E, Diczfalusy U, Iuliano L. Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque. Arterioscler Thromb Vasc Biol 2004;24:136-140.
27. Iuliano L, Micheletta F, Natoli S, Ginanni Corradini S, Iappelli M, Elisei W, et al. Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status. Anal Biochem 2003;312:217-223.
28. Zhou Q, Wasowicz E, Handler B, Fleischer L, Kummerow FA. An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells. Atherosclerosis 2000;149:191-197.
29. Gonzalez FX, Rimola A, Grande L, Antolin M, Garcia-Valdecasas JC, Fuster J, et al. Predictive factors of early postoperative graft function in human liver transplantation. Hepatology 1994; 20:565-573.
30. Chui AKK, Haghighi K, Painter D, Jayasundera M, Hall G, Rao ARN, et al. Donor fatty (steatotic) liver allograft in orthotopic liver transplantation. Transplant Proc 1998;30:3286-3287.
31. Nanashima A, Pillay P, Verran DJ, Painter D, Nakasuji M, Crawford M, et al. Analysis of initial poor graft function after orthotopic liver transplantation: experience of an Australian single liver transplantation center. Transplant Proc 2002;34:1231-1235.
32. Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation 2003;108:1912-1916.
33. Moore K. Isoprostanes and the liver. Chem Phys Lipids 2004; 128:125-133.
34. Mol MJ, de Rijke YB, Demacker PN, Stalenhoef AF. Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment. Atherosclerosis 1997;129:169-176.
35. Salonen JT, Nyyssonen K, Salonen R, Porkkala-Sarataho E, Tuomainen TP, Diczfalusy U, et al. Lipoprotein oxidation and progression of carotid atherosclerosis. Circulation 1997;95:840-845.
36. Look MP, Reichel C, von Falkenhausen M, Hahn C, Stockinger K, von Bergmann K, et al. Vitamin E status in patients with liver cirrhosis: normal or deficient? Metabolism 1999;48:86-91.
37. Patel RP, Diczfalusy U, Dzeletovic S, Wilson MT, Darley-Usmar VM. Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper. J Lipid Res 1996;37:2361-2371.
38. Rusinol AE, Thewke D, Liu J, Freeman N, Panini SR, Sinensky MS. AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis. J Biol Chem 2004;279: 1392-1399.
39. Pirillo A, Zhu W, Roma P, Galli G, Caruso D, Pellegatta F, et al. Oxysterols from oxidized LDL are cytotoxic but fail to induce hsp70 expression in endothelial cells. FEBS Lett 1999;462:113-116.
40. Meynier A, Andre A, Lherminier J, Grandgirard A, Demaison L. Dietary oxysterols induce in vivo toxicity of coronary endothelial and smooth muscle cells. Eur J Nutr. 2005-Jan 27:[Epub ahead of print].
41. Ljubuncic P, Tanne Z, Bomzon A. Evidence of a systemic phenomenon for oxidative stress in cholestatic liver disease. Gut 2000;47:710-716.
42. Stocker A, Azzi A. Tocopherol-binding proteins: their function and physiological significance. Antioxid Redox Signal 2000;2: 397-404.
43. Crovatto M, Pozzato G, Zorat F, Pussini E, Nascimben F, Baracetti S, et al. Peripheral blood neutrophils from hepatitis C virus-infected patients are replication sites of the virus. Haematologica 2000;85:356-361.
44. Garcia-Retortillo M, Forns X, Feliu A, Moitinho E, Costa J, Navasa M, et al. Hepatitis C virus kinetics during and immediately after liver transplantation. Hepatology 2002;35: 680-687.
45. Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM, et al. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002;122:366-375.
46. Gong G, Waris G, Tanveer R, Siddiqui A. Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci U S A 2001;98:9599-9604.