Idefix insulator activity can be modulated by nearby regulatory elements

Nucleic Acids Research

Volumn 35, Issue 8, 2007, Pages 2661-2670

  Brasset, E ^a   Bantignies, F ^b   Court, F ^a   Cheresiz, S ^c   Conte, C ^d   Vaury, Chantal ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSTITUTE OF HUMAN GENETICS   (France)

^c INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5' UNTRANSLATED REGION; ARTICLE; CHROMATIN; CONTROLLED STUDY; DROSOPHILA; GENE CONTROL; GENE FUNCTION; GENE LOCUS; GENE SEQUENCE; GENETIC ANALYSIS; GENOMICS; INSULATOR ELEMENT; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; RETROPOSON; ANIMAL; CELL NUCLEUS; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; GENOME; REGULATORY SEQUENCE; TRANSGENE;

5' UNTRANSLATED REGIONS; ANIMALS; CELL NUCLEUS; DROSOPHILA; GENE EXPRESSION REGULATION; GENOME; INSULATOR ELEMENTS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; RETROELEMENTS; TERMINAL REPEAT SEQUENCES; TRANSGENES;

EID: 34250312403     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm140     Document Type: Article

References (39)

1. West,A.G. and Fraser,P. (2005) Remote control of gene transcription. Hum. Mol. Genet., 14(Spec. No. 1), R101-R111
2. Dorsett,D. (1999) Distant liaisons: Long-range enhancer-promoter interactions in drosophila. Curr. Opin. Genet. Dev., 9, 505-514.
3. Carter,D., Chakalova,L., Osborne,C.S., Dai,Y.F. and Fraser,P. 2002) Long-range chromatin regulatory interactions in vivo. Natl Genet., 32, 623-626.
4. de Laat,W. and Grosveld,F. (2003) Spatial organization of gene expression: The active chromatin hub. Chromosome Res., 11, 447-459.
5. Palstra,R.J., Tolhuis,B., Splinter,E., Nijmeijer,R., Grosveld,F. and de Laat,W. (2003) The beta-globin nuclear compartment in development and erythroid differentiation. Nat. Genet., 35, 190-194.
6. Kellum,R. and Schedl,P. (1991) A position-effect assay for boundaries of higher order chromosomal domains. Cell, 64, 941-950.
7. Kellum,R. and Schedl,P. (1992) A group of scs elements function as domain boundaries in an enhancer-blocking assay. Mol. Cell. Biol., 12, 2424-2431.
8. Brasset,E. and Vaury,C. (2005) Insulators are fundamental components of the eukaryotic genomes. Heredity, 94, 571-576.
9. Cai,H.N. and Shen,P. (2001) Effects of cis arrangement of chromatin insulators on enhancer-blocking activity. Science, 291, 493-495.
10. Muravyova,E., Golovnin,A., Gracheva,E., Parshikov,A., Belenkaya,T., Pirrotta,V. and Georgiev,P. (2001) Loss of insulator activity by paired Su(Hw) chromatin insulators. Science, 291, 495-498.
11. Kravchenko,E., Savitskaya,E., Kravchuk,O., Parshikov,A., Georgiev,P. and Savitsky,M. (2005) Pairing between gypsy insulators facilitates the enhancer action in trans throughout the Drosophila genome. Mol. Cell. Biol., 25, 9283-9291.
12. Gerasimova,T.I., Byrd,K. and Corces,V.G. (2000) A chromatin insulator determines the nuclear localization of DNA. Mol. Cell, 6, 1025-1035.
13. Cai,H. and Levine,M. (1995) Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo [see comments]. Nature, 376, 533-536.
14. Scott,K.S. and Geyer,P.K. (1995) Effects of the su(Hw) insulator protein on the expression of the divergently transcribed Drosophila yolk protein genes. EMBO J., 14, 6258-6267.
15. Desset,S., Conte,C., Dimitri,P., Calco,V., Dastugue,B. and Vaury,C. (1999) Mobilization of two retroelements, ZAM and Idefix, in a novel unstable line of Drosophila melanogaster. Mol. Biol. Evol., 16 54-66.
16. Conte,C., Dastugue,B. and Vaury,C. (2002) Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genes. Mol. Cell. Biol., 22, 1767-1777.
17. Majumder,P. and Cai,H.N. (2003) The functional analysis of insulator interactions in the Drosophila embryo. Proc. Natl Acad. Sci. USA, 100, 5223-5228.
18. Gerasimova,T.I. and Corces,V.G. (2001) Chromatin insulators and boundaries: Effects on transcription and nuclear organization. Annu. Rev. Genet., 35, 193-208.
19. Kuhn,E.J. and Geyer,P.K. (2003) Genomic insulators: Connecting properties to mechanism. Curr. Opin. Cell. Biol., 15, 259-265.
20. Oki,M. and Kamakaka,R.T. (2002) Blockers and barriers to transcription: competing activities? Curr. Opin. Cell. Biol., 14, 299-304.
21. Xu,Q., Li.M., Adams,J. and Cai,H.N. (2004) Nuclear location of a chromatin insulator in Drosophila melanogaster. J. Cell. Sci., 117, 1025-1032.
22. Byrd,K. and Corces,V.G. (2003) Visualization of chromatin domains created by the gypsy insulator of Drosophila. J. Cell. Biol., 162, 565-574.
23. Sigrist,C.J. and Pirrotta,V. (1997) Chromatin insulator elements block the silencing of a target gene by the Drosophila polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes. Genetics, 147, 209-221.
24. Blanton,J., Gaszner,M. and Schedl,P. (2003) Protein: Protein interactions and the pairing of boundary elements in vivo. Genes Dev. 17, 664-675.
25. Ishii,K., Arib,G., Lin,C., Van Houwe,G. and Laemmli,U.K. (2002) Chromatin boundaries in budding yeast: The nuclear pore connection. Cell, 109, 551-562.
26. Cockerill,P.N. and Garrard,W.T. (1986) Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell, 44, 273-282.
27. Forrester,W.C., Fernandez,L.A. and Grosschedl,R. (1999) Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions. Genes Dev., 13, 3003-3014.
28. Loc,P. and Strätling.W. (1988) The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain. EMBO J., 7, 655-664.
29. McKnight,R.A., Shamay,A., Sankaran,L., Wall,R.J. and Hennighausen,L. (1992) Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice. Proc. Natl Acad. Sci. USA, 89, 6943-6947.
30. Spilianakis,C.G, Lalioti,M.D, Town,T., Lee,G.R. and Flavell,R.A. (2005) Interchromosomal associations between alternatively expressed loci. Nature, 435, 579-580.
31. Brown,J.M., Leach,J., Reittie,J.E., Atzberger,A., Lee-Prudhoe,J., Wood,W.G., Higgs,D.R., Iborra,F.J. and Buckle,V.J. (2006) Coregulated human globin genes are frequently in spatial proximity when active. J. Cell. Biol., 172, 177-187.
32. Muller,M., Hagstrom,K., Gyurkovics,H., Pirrotta,V. and Schedl,P. (1999) The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions. Genetics, 153 1333-1356.
33. Bantignies,F., Grimaud,C., Lavrov,S., Gabut,M. and Cavalli,G. (2003) Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev., 17, 2406-2420.
34. Mihaly,J., Flogga,I., Gausz,J., Gyurkovics,H. and Karch,F. (1997) In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element. Development, 124, 1809-1820.
35. Gruzdeva,N., Kyrchanova,O., Parshikov,A., Kullyev,A. and Georgiev,P. (2005) The mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication. Mol. Cell. Biol., 25, 3682-3689.
36. Rubin,G.M. and Spradling,A.C. (1982) Genetic transformation of Drosophila with transposable element vectors. Science, 218, 348-353.
37. Ahmad,K. and Golic,K.G. (1996) Somatic reversion of chromosomal position effects in Drosophila melanogaster. Genetics, 144, 657-670.
38. Evans,B.A. and Howells,A.J. (1978) Control of drosopterin synthesis in Drosophila melanogaster: Mutants showing an altered pattern of GTP cyclohydrolase activity during development. Biochem. Genet., 16 13-26.
39. Cryderman,D.E., Cuaycong,M.H., Elgin,S.C. and Wallrath,L.L. (1998) Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin. Chromosoma, 107, 277-285.