Protein:protein interactions and the pairing of boundary elements in vivo

Genes and Development

Volumn 17, Issue 5, 2003, Pages 664-675

  Blanton, Jason ^b   Gaszner, Miklos ^a   Schedl, Paul ^b  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b NONE

Author keywords

Boundaries; Domains; Insulators; Looping; Pairing; Protein:protein interaction

Indexed keywords

BEAF PROTEIN; PROTEIN; UNCLASSIFIED DRUG; ZW5 PROTEIN;

ARTICLE; CELL STRUCTURE; CHROMATIN; CHROMOSOMAL LOCALIZATION; CHROMOSOME; DROSOPHILA; EMBRYO; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; DNA; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EYE PROTEINS; INSULATOR ELEMENTS; NUCLEAR PROTEINS; PROTEIN BINDING;

EUKARYOTA;

EID: 0037338603     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1052003     Document Type: Article

References (40)

1. Bell, A.C., West, A.G., and Felsenfeld, G. 2001. Insulators and boundaries: Versatile regulatory elements in the eukaryotic genome. Science 291: 447-450.
2. Bellard, M., Kuo, M.T., Dretzen, G., and Chambon, P. 1980. Differential nuclease sensitivity of the ovalbumin and β-globin chromatin regions in erythrocytes and oviduct cells of laying hen. Nucleic Acids Res. 8: 2737-2750.
3. Cai, H.N. and Shen, P. 2001. Effects of cis arrangement of chromatin insulators on enhancer-blocking activity. Science 291: 493-495.
4. Chung, J.H., Whiteley, M., and Felsenfeld, G. 1993. A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74: 505-514.
5. Cuvier, O., Hart, C.M., and Laemmli, U.K. 1998. Identification of a class of chromatin boundary elements. Mol. Cell. Biol. 18: 7478-7486.
6. Cuvier, O., Hart, C.M., Kas, E., and Laemmli, U.K. 2002. Identification of a multicopy chromatin boundary element at the borders of silenced chromosomal domains. Chromosoma 110: 519-531.
7. Dekker, J., Rippe, K., Dekker, M., and Kleckner, N. 2002. Capturing chromosome conformation. Science 295: 1306-1311.
8. Gaszner, M., Vazquez, J., and Schedl, P. 1999. The Zw5 protein, a component of the scs chromatin domain boundary, is able to block enhancer-promoter interaction. Genes & Dev. 13: 2098-2107.
9. Gerasimova, T.I. and Corces, V.G. 2001. Chromatin insulators and boundaries: Effects on transcription and nuclear organization. Ann. Rev. Genet. 35: 193-208.
10. Gerasimova, T.I., Byrd, K., and Corces, VG. 2000. A chromatin insulator determines the nuclear localization of DNA. Mol. Cell 6: 1025-1035.
11. Geyer, P.K. 1997. The role of insulator elements in defining domains of gene expression. Curr. Opin. Genet. Dev. 7: 242-248.
12. Geyer, P. and Corces, V. 1992. DNA position-specific repression of transcription by a Drosophila zinc finger protein. Genes & Dev. 6: 1865-1973.
13. Glover, D.M., Leibowitz, M.H., McLean, D.A., and Parry H. 1995. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell 81: 95-105.
14. Grewal, S.I. 2000. Transcriptional silencing in fission yeast. J. Cell Physiol. 184: 311-318.
15. Gyurkovics, H., Gausz, J., Kummer, J., and Karch, F. 1990. A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation. EMBO J. 9: 2579-2585.
16. Hart, C.M., Zhao, K., and Laemmli, U.K. 1997. The scs' boundary element: Characterization of boundary element-associated factors. Mol. Cell. Biol. 17: 999-1009.
17. Hebbes, T.R., Clayton, A.L., Thorne, A., and Crane-Robinson, C. 1992. Core histone hyperacetylatiopn co-maps with generalized DNase I sensitivity in the chicken β-globin chromosomal domain. EMBO J. 13: 1823-1830.
18. Hogga, I., Mihaly, J., Barges, S., and Karch, F. 2001. Replacement of Fab-7 by the gypsy or scs insulator disrupts long-distance regulatory interactions in the Abd-B gene of the bithorax complex. Mol. Cell 8: 1145-1151.
19. Holdridge, C. and Dorsett, D. 1991. Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster. Mol. Cell. Biol. 11: 1894-1900
20. Huang, Y. 2002. Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Nucleic Acids Res. 30: 1465-1482.
21. Kellum, R. and Schedl, P. 1991. A position effect assay for boundaries of higher order chromatin domains. Cell 64: 941-951.
22. -. 1992. A group of scs elements function as domain boundaries in an enhancer-blocking assay. MCB 12: 2424-2431.
23. Litt, M.D., Simpson, M., Gaszner, M., Allis, C.D., and Felsenfeld, G. 2001a. Correlation between histone lysine methylation and developmental changes at the chicken β-globin locus. Science 293: 2453-2455.
24. Litt, M.D., Simpson, M., Recillas-Targa, F., Prioleau, M.N., and Felsenfeld, G. 2001b. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. EMBO J. 20: 2224-2235.
25. Marsden, M.P. and Laemmli, U.K. 1979. Metaphase chromosome structure: Evidence for a radial loop model. Cell 17: 849-858.
26. Muller, M., Hagstrom, K., Gyurkovics, H., Pirrotta, V., and Schedl, P. 1999. The Mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions. Genetics 153: 1333-1356.
27. Muravyova, E., Golovnin, A., Gracheva, E., Parshikov, A., Belenkaya, T., Pirrotta, V., and Georgiev, P. 2001. Loss of insulator activity by paired Su(Hw) chromatin insulators. Science 291: 495-498.
28. Noma, K., Allis, C.D., and Grewal, S.I. 2001. Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries. Science 293: 1150-1155.
29. Orlando, V. and Paro, R. 1993. Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin. Cell 75: 1187-1198.
30. Saitoh, N., Bell, A.C., Recillas-Targa, F., West, A.G., Simpson, M., Pikaart, M., and Felsenfeld, G. 2000. Structural and functional conservation at the boundaries of the chicken β-globin domain. EMBO J. 19: 2315-2322
31. Sigrist, C.J. and Pirrotta, V. 1997. Chromatin insulator elements block the silencing of a target gene by the Drosophila Polycomb Response Element (PRE) but allow trans interactions between PREs on different chromosomes. Genetics 147: 209-221.
32. Stalder, J., Larsen, A., Engel, J.D., Dolan, M., Groudine, M., and Weintraub, H. 1980. Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I. Cell 20: 451-460.
33. Thon, G., Bjerling, P., Bunner, C.M., and Verhein-Hansen, J. 2002. Expression-state boundaries in the mating-type region of fission yeast. Genetics 161: 611-622.
34. Udvardy, A. 1999. Dividing the empire: Boundary chromatin elements delimit the territory of enhancers. EMBO J. 18: 1-8.
35. Udvardy, A., Maine, E., and Schedl, P. 1985. The 87A7 chromomere: Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains. J. Mol. Biol. 185: 341-358.
36. Vazquez J. and Schedl, P. 1994. Sequences required for enhancer blocking activity of scs are located within two nucleasehypersensitive regions. EMBO J. 13: 5984-5993.
37. Verreault, A. and Thomas, J.O. 1993. Chromatin structure of the β-globin chromosomal domain in adult chicken erythrocytes. Cold Spring Harb. Symp. Quant. Biol. 58: 15-24.
38. West, A.G., Gaszner, M., and Felsenfeld, G. 2002. Insulators: Many functions, many mechanisms. Genes & Dev. 16: 271-288.
39. Yamaguchi M., Yoshida, H., Hirose, F., Inoue, Y.H., Hayashi, Y., Yamagishi, M., Nishi, Y., Tamai, K., Sakaguchi, K. and Matsukage A. 2001. Ectopic expression of BEAF32A in the Drosophila eye imaginal disc inhibits differentiation of photoreceptor cells and induces apoptosis. Chromosoma 110: 313-321.
40. Zhao, K., Hart, C.M., and Laemmli, U.K. 1995. Visualization of chromosomal domains with boundary element-associated factor BEAF-32. Cell 81: 879-889.