Role of topical calcineurin inhibitors on atopic dermatitis of children

Current Medicinal Chemistry

Volumn 14, Issue 14, 2007, Pages 1579-1591

  Ricci, Giampaolo ^a,b   Dondi, A ^a   Patrizi, A ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Department of Pediatrics ^*  (Italy)

Author keywords

Atopic dermatitis; Pimecrolimus; Tacrolimus; Topical calcineurin inhibitors

Indexed keywords

ANTIINFLAMMATORY AGENT; BETAMETHASONE VALERATE; CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM; CORTICOSTEROID; CYCLOSPORIN; CYTOKINE; EMOLLIENT AGENT; HYDROCORTISONE ACETATE; HYDROCORTISONE BUTYRATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 2; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN; PIMECROLIMUS; PROTEIN SERINE THREONINE KINASE; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; TRIAMCINOLONE ACETONIDE;

ACNE; ALCOHOL INTOLERANCE; ALLERGY; APPLICATION SITE REACTION; ASTHMA; ATOPIC DERMATITIS; BACTERIAL INFECTION; BRAIN TISSUE; BRONCHITIS; CARCINOGENICITY; CHICKENPOX; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; COUGHING; DIARRHEA; DISEASE SEVERITY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; DRUG PENETRATION; DRUG SAFETY; DRUG STRUCTURE; DRUG WITHDRAWAL; EAR INFECTION; ECZEMA; ENZYME INHIBITION; ERYTHEMA; FEVER; FLU LIKE SYNDROME; FOLLICULITIS; FOOD AND DRUG ADMINISTRATION; GASTROENTERITIS; GENETIC TRANSCRIPTION; HAND FOOT AND MOUTH DISEASE; HEADACHE; HEART VALVE; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; HYPERESTHESIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INHIBITION KINETICS; LYMPHOCYTE ACTIVATION; LYMPHOMA; MACULOPAPULAR RASH; META ANALYSIS; MOLLUSCUM CONTAGIOSUM; MORPHOGENESIS; MUSCLE DEVELOPMENT; NERVOUS SYSTEM DEVELOPMENT; PHARYNGITIS; PROTEIN DEPHOSPHORYLATION; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; REVIEW; RHINITIS; RHINOPHARYNGITIS; SIDE EFFECT; SIGNAL TRANSDUCTION; SINUSITIS; SKELETAL MUSCLE; SKIN BURNING SENSATION; SKIN TINGLING; SQUAMOUS CELL CARCINOMA; SYSTEMATIC REVIEW; UPPER RESPIRATORY TRACT INFECTION; VERRUCA VULGARIS; VOMITING;

ADMINISTRATION, TOPICAL; ANIMALS; CALCINEURIN; CHILD; DERMATITIS, ATOPIC; DRUG TOXICITY; ENZYME INHIBITORS; HUMANS; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 34250214551     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986707780831032     Document Type: Review

References (101)

1. Williams, H.; Robertson, C.; Stewart, A.; Ait- Khaled, N.; Anabwani, G.; Anderson, R.; Asher, I.; Beasley, R.; Bjorksten, B.; Burr, M.; Clayton, T.; Crane, J.; Ellwood, P.; Keil, U.; Lai, C.; Mallol, J.; Martinez, F.; Mitchell, E.; Montefort, S.; Pearce, N.; Shah, J.; Sibbald, B.; Strachan, D.; von Mutius, E.; Weiland, S.K. J. Allergy Clin. Immunol. 1999, 103, 125-38.
2. Hanifin, J.M. Immunol. Allergy Clin. NA 2002, 22, 1-24.
3. Eichenfield, L.F. Allergy 2004, 59 (Suppl 78), 86-92.
4. Castro, A.P. J. Pediatr. (Rio J.) 2006, 82 (Suppl 5), S166-72.
5. Simpson, D.; Noble, S. Drugs 2005, 65, 827-58.
6. Wollina, U.; Hansel, G.; Koch, A.; Abdel-Naser, M.B. Expert Opin. Pharmacother. 2006, 7, 1967-75.
7. Hows, J. M.; Palmer, S.; Gordon-Smith, E.C. Tansplantation 1982, 33, 382-6.
8. Lauerma, A.I.; Suber, C.; Maibach, H.I. Skin Pharmacol. 1997, 10, 230-4.
9. Kino, T.; Hatanaka, H.; Miyata, S.; Inamura, N.; Nishiyama, M.; Yajima, T.; Goto, T.; Okuhara, M.; Kohsaka, M.; Aoki, H. J. Antibiot. 1987, 40, 1256-65.
10. Goto, T., Kino, T.; Hatanaka, H.; Okuhara, M.; Kohsaka, M.; Aoki, H. Transplant. Proc. 1991, 23, 2713-7.
11. Reitamo, S. In Tacrolimus Ointment: A topical immunomodulator for atopic dermatitis, T. Ruzicka, S. Reitamo, Eds; Springer-Verlag: Berlin Heidelberg, 2004; Part II, Chap 6, pp. 101.
12. Alaiti, S.; Kang, S.; Fiedler, V.C.; Ellis, C.N.; Spurlin, D.V.; Fader, D.; Ulyanov, G.; Gadgil, S.D.; Tanase, A.; Lawrence, I.; Scotellaro, P.; Raye, K.; Bekersky, I. J. Am. Acad. Dermatol. 1998, 38, 69-76.
13. Michel, G.; Kemeny, L.; Homey, B.; Ruzicka, T. Immunol. Today 1996, 17, 106-8.
14. Reitamo, S. In Tacrolimus Ointment: A topical immunomodulator for atopic dermatitis, T. Ruzicka, S. Reitamo, Eds; Springer-Verlag: Berlin Heidelberg, 2004; Part III, Chap 10, pp. 200.
15. Hultsch, T.; Muller, K.D.; Meingassner, J.G.; Grassberger, M.; Schopf, R.E.; Knop, J. Arch. Dermatol. Res. 1998, 290, 501-7.
16. Grassberger, M.; Baumruker, T.; Enz, A.; Hiestand, P.; Hultsch, T.; Kalthoff, F.; Schuler, W.; Schulz, M.; Werner, F.J.; Winiski, A.; Wolff, B.; Zenke, G. Br. J. Dermatol. 1999, 141, 264-73
17. Billich, A.; Aschauer, H.; Aszódi A.; Stuetz, A. Int. J. Pharm. 2004, 269, 29-35.
18. Halloran, P.F. Lancet 2000, 356, 179-80.
19. Hughes, J.; Rustin, M. Clin. Dermatol. 1997, 15, 715-21.
20. Norris, D.A. J. Am. Acad. Dermatol. 2005, 53, S17-25.
21. Schainman, R.I.; Cogswell, P.C.; Lofquist, A.K.; Baldwin, A.S.jr. Science 1995, 270, 283-6.
22. Auphan, N.; Di Donato, J.A.; Rosette, C.; Helberg, A.; Karin, M. Science 1995, 270, 286-90.
23. Guerini, D.; Klee, C.B. Proc. Natl. Acad. Sci. USA 1989, 86, 9183-7.
24. Semsarian, C.; Wu, M.J.; Ju, Y.K.; Marciniec, T.; Yeoh, T.; Allen, D.G.; Harvey, R.P.; Graham, R.M. Nature 1999, 400, 576-81.
25. Musaro, A.; Mc Cullagh, K.J.; Naya, F.J.; Olson, Rosenthal, N. Nature 1999, 400, 581-5.
26. Flanagan, W.M.; Corthesy, B.; Bram, R.J.; Crabtree, G.R. Nature 1991, 29, 352, 803-7.
27. Loh, C.; Shaw, K.T.; Carew, J.; Viola, J.P.; Luo, C.; Perrino, B.A.; Rao, A. J. Biol. Chem. 1996, 271, 10884-91.
28. Rao, A. Immunol. Today 1994, 15, 274-81.
29. Cirillo, R.; Triggiani, M.; Siri, L.; Ciccarelli, A.; Pettit, G.R.; Condorelli, M.; Marone, G. J. Immunol. 1990, 144, 3891-7.
30. Kotturi, M.F.; Hunt, S.V.; Jefferies, W.A. Trends Pharmacol. Sci. 2006, 27, 360-7.
31. Thomson, A.W.; Bonham, C.A.; Zeevi, A. Ther. Drug Monit. 1995, 17, 584-91.
32. Hultsch, T.; Brand, P.; Lohmann, S.; Saloga, J.; Kincaid, R.L.; Knop, J. Arch. Dermatol. Res. 1998, 290, 258-63.
33. Panhans-Gross, A.; Novak, N.; Kraft, S.; Bieber, T. J. Allergy Clin. Immunol. 2001, 107, 345-52.
34. Bornhovd, E.C.; Burgdorf, W.H.C.; Wollenberg, A. Curr. Opin. Investig. Drugs 2002, 3, 708-12.
35. Wollenberg, A.; Wen, S.; Bieber, T. Cytometry 1999, 37, 147-55.
36. Schuller, E.; Oppel, T.; Bornhovd, E.; Wetzel, S.; Wollenberg, A. J. Allergy Clin. Immunol. 2004, 114, 137-43.
37. Wollenberg, A.; Sharma, S.; von Bubnoff, D.; Geiger, E.; Haberstok, J.; Bieber, T. J. Allergy Clin. Immunol. 2001, 107, 519-25.
38. Gisondi, P.; Ellis, C.N.; Girolomoni, G. Int. J. Clin. Pract. 2005, 59, 969-74.
39. Grassberger, M.; Steinhoff, M.; Schneider, D.; Luger, T.A. Exp. Dermatol. 2004, 13, 721-30.
40. Hofman, T.; Cranswick, N.; Kuna, P.; Boznanski, A.; Latos, T.; Gold, M.; Murell, D.; Gebauer, K.; Behre, U.; Machura, E.; Oacutelafsson, J.; Szalai, Z. Arch. Dis. Child. 2006, 23 (Epub ahead of print).
41. Papp, K.A.; Breuer, K.; Meurer, M.; Ortonne, J.P.; Potter, P.C.; de Prost, Y.; Davidson, M.J.; Barbier, N.; Goertz, H.P.; Paul, C. J. Am. Acad. Dermatol. 2005, 52, 247-53.
42. Stander, S.; Luger, T.A. Hautarzt 2003, 54, 413-7
43. Queille-Roussel, C.; Paul, C.; Duteil, L.; Lefebvre, M.C.; Rapatz, G.; Zagula, M.; Ortonne, J.P. Br. J. Dermatol. 2001, 144, 507-13.
44. Meingassner, J.G.; Stutz, A. J. Invest. Dermatol. 1992, 98, 851-5.
45. Sengoku, T.; Morita, K.; Sato, S. Folia Pharmacol. Jpn. 1998, 112, 221-32.
46. Reitamo, S.; Rissanen, J.; Remitz, A.; Granlund, H.; Erkko, P.; Elg, P.; Autio, P.; Lauerma, A.I. J. Invest. Dermatol. 1998, 111, 396-8.
47. Kyllonen, H.; Remitz, A.; Mandelin, J.M. Br. J. Dermatol. 2004, 150, 1174-81.
48. Hultsch, T.; Kapp, A.; Spergel, J. Dermatology 2005, 211, 174-187.
49. Allen, B.R. J. Allergy Clin. Immunol. 2002, 109, 401-3.
50. Allen, B.R.; Lakhanpaul, M.; Morris, A.; Lateo, S.; Davies, T.; Scott, G.; Cardno, M.; Ebelin, M.E.; Burtin, P.; Stephenson, T.J. Arch. Dis. Child. 2003, 88, 969-73.
51. Oji, V.; Beljan, G.; Beier, K.; Traupe, H.; Luger, T.A. Br. J. Dermatol. 2005, 13, 1067-1092.
52. Paller, A.; Eichenfield, L.F.; Leung, D.Y.; Stewart, D.; Appell, M. J. Am. Acad. Dermatol. 2001, 44(Suppl 1), S47-57.
53. Hanifin J.M.; Ling, M.R.; Langley, R.; Breneman, D.; Rafal, E. J. Am. Acad. Dermatol. 2001, 44(Suppl 1), S28-38.
54. Harper, J.; Smith, C.; Rubins, A.; Green, A.; Jackson, K.; Zigure, S.; Bourke, J.; Alomar, A.; Stevenson, P.; Foster, C.; Undre, N. J. Invest. Dermatol. 2005, 124, 695-9.
55. Rubins, A.; Gutmane, R.; Valdmane, N.; Stevenson, P.; Foster, C.; Undre, N. J. Invest. Dermatol. 2005, 125, 68-71.
56. Alomar, A.; Berth-Jones, J.; Bos, J.D.; Giannetti, A.; Reitamo, S.; Ruzicka, T.; Stalder, J.F.; Thestrup-Pedersen, K.; European Working Group on Atopic Dermatitis. Br. J. Dermatol. 2004, 151(Suppl 70), 3-27.
57. Reitamo, S.; Wollenberg, A.; Schöpf, E.; Perrot, J.L.; Marks, R.; Ruzicka, T.; Christophers, E.; Kapp, A.; Lahfa, M.; Rubins, A.; Jablonska, S.; Rustin, M. Arch. Dermatol. 2000, 136, 999-1006.
58. Draelos, Z.; Nayak, A.; Pariser, D., Shupack, J.L.; Chon, K.; Abrams, B.; Paul, C.F. J. Am. Acad. Dermatol. 2005, 53, 602-9.
59. Hanifin, J.M.; Rajka, G. Acta Dermatovener. 1980, (Suppl 92), 44-47.
60. Williams, H.C.; Burney, P.G.; Pembroke, A.C.; Hay, R.J. Br. J. Dermatol. 1994, 131, 406-16.
61. Seymour, J.L.; Keswick, B.H. Hanifin, J.M.; Jordan, W.P.; Milligan, M.C. J. Am. Acad. Dermatol. 1987, 17, 988-97.
62. Rajka, G.; Langeland, T. Acta Dermatol. Venereol. Suppl. 1989, 144, 13-4.
63. Eichenfield, L.F.; Lucky, A.W.; Boguniewicz, M.; Langley, R.G.B.; Cherill, R.; Marshall, K.; Bush, C.; Graeber, M. J. Am. Acad. Dermatol. 2002, 46, 495-504.
64. Schachner, L.A.; Lamerson, C.; Sheehan, M.P.; Boguniewicz, M.; Mosser, J.; Raimer, S.; Shull, T.; Jaracz, E. Pediatrics 2005, 116, 334-42.
65. Hanifin, J.M.; Thurston, M.; Omoto, M.; Cherill, R.; Tofte, S.J.; Graeber, M. Exp. Dermatol. 2001, 10, 11-8.
66. Reitamo, S.; Rustin, M.; Ruzicka, T.; Cambazard, F.; Kalimo, K.; Friedmann, P.S.; Schoepf, E.; Lahfa, M.; Diepgen, T.L.; Judodihardjo, H. J. Allergy Clin. Immunol. 2002, 109, 547-55.
67. Ruzicka, T.; Bieber, T.; Schöpf, E.; Rubins, A.; Dobozy, A.; Bos, J.D.; Jablonska, S.; Ahmed, I.; Thestrup-Pedersen, K.; Daniel, F.; Finzi, A.; Reitamo, S. N. Engl. J. Med. 1997, 337, 816-21.
68. Chapman, M.S.; Schachner, L.A.; Breneman, D.; Boguniewicz, M.; Gold, M.H.; Shull, T.; Linowski, G.J.; Jaracz, E. J. Am. Acad. Dermatol. 2005, 53, S177-85.
69. Boguniewicz, M.; Fiedler, V.C.; Raimer, S.; Lawrence, I.D.; Leung, D.Y.; Hanifin, J.M. J. Allergy Clin. Immunol. 1998, 102, 637-44.
70. Meurer, M.; Fölster-Holst, R.; Wozel, G.; Weidinger, G.; Jünger, M.; Bräutigam, M. Dermatology 2002, 205, 271-77.
71. Meurer, M.; Fartasch, M.; Albrecht, G.; Vogt, T.; Worm, M.; Ruzicka, T.; Altmeyer, P.J.; Schneider, D.; Weidinger, G.; Braeutigam, M. Dermatology 2004, 208, 365-72.
72. Luger, T.; Van Leent, E.J.M.; Graeber, M.; Hedgecock, S.; Thurston, M.; Kandra, A.; Berth-Jones, J.; Bjerke, J.; Christophers, E.; Knop, J.; Knulst, A.C.; Morren, M.; Morris, A.; Reitamo, S.; Roed-Petersen, J.; Schoepf, E.; Thestrup-Pedersen, K.; Van Der Valk, P.G.M.; Bos, J.D. Br. J. Dermatol. 2001, 144, 798-94.
73. Kapp, A.; Papp, K.; Bingham, A.; Fölster-Holst, R.; Ortonne, J.P.; Potter, P.C.; Gulliver, W.; Paul, C.; Molloy, S.; Barbier, N.; Thurston, M.; de Prost, Y. J. Allergy Clin. Immunol. 2002, 110, 277-84.
74. Wahn, U.; Bos, J.D.; Goodfield, M.; Caputo, R.; Papp, K.; Manjra, A.; Dobozy, A.; Paul, C.; Molloy, S.; Hultsch, T.; Graeber, M.; Cherill R.; de Prost, Y. Pediatrics 2002, 110, e2.
75. Barba, J.F.; Beirana, A.; Cohen, V.; Dominiguez, L.; Duran, C.; Leon, G.; Montes de Oca, F.; Ocampo, J.; Welch, O. J. Eur. Acad. Dermatol. Venereol. 2003, 17(Suppl 3), 182.
76. Ho, V.C.; Gupta, A.; Kaufmann, R.; Todd, G.; Vanaclocha, F.; Takaoka, R.; Fölster-Holst, R.; Potter, P.; Marshall, K.; Thurston, M.; Bush, C.; Cherill, R. J. Pediatr. 2003, 142, 155-62.
77. Papp, K.; Staab, D.; Harper, J.; Potter, P.; Puig, L.; Ortonne, J.P.; Molloy, S.; Barbier, N.; Paul, C. Int. J. Dermatol. 2004, 43, 978-83.
78. Reitamo, S.; Ortonne, J.P.; Sand, C.; Cambazard, F.; Bieber, T.; Fölster-Holst, R.; Vena, G.; Bos, J.D.; Fabbri, P.; Groenhoej Larsen, C. Br. J. Dermatol. 2005, 152, 1282-89
79. Reitamo, S.; Van Leent E.J.M.; Ho, V.; Harper, J.; Ruzicka, T.; Kalimo, K.; Cambazard, F.; Rustin, M.; Taïeb, A.; Gratton, D.; Sauder, D.; Sharpe, G.; Smith, C.; Jünger, M.; de Proste, Y. J. Allergy Clin. Immunol. 2002, 109, 539-46.
80. Reitamo, S.; Harper, J.; Bos, J.D.; Cambazard, F.; Bruijnzeel-Koomen, C.; Valk, P.; Smith, C.; Moss, C.; Dobozy, A.; Palatsi, R. Br. J. Dermatol. 2004, 150, 554-62.
81. Luger, T.A.; Lahfa, M.; Fölster-Holst, R.; Gulliver, W.P.; Aller, R.; Molloy, S.; Barbier, N.; Paul, C.; Bos, J.D. J. Dermatol. Treat. 2004, 15, 169-78.
82. Paller, A.S.; Lebwohl, M.; Fleischer, A.B.; Antaya, R.; Langley, R.G.; Kirsner, R.S.; Blum, R.R.; Rico, M.J.; Jaracz, E.; Crowe, A.; Linowski, G.J. J. Am. Acad. Dermatol. 2005, 52, 810-22.
83. Kempers, S.; Boguniewicz, M.; Carter, E.; Jarratt, M.; Pariser, D.; Stewart, D.; Still, M.; Tschen, E.; Chon, K.; Wisseh, S.; Abrams, B. J. Am. Acad. Dermatol. 2004, 51, 515-25.
84. Patrizi, A.; Neri, I.; Bianchi, F.; Ricci, G. Pediatr. Dermatol., in press.
85. Ashcroft, D.M.; Dimmock, P.; Garside, R.; Stein, K.; Williams, H.C. B.M.J. 2005, 330, 516.
86. Papp, K.A.; Werfel, T.; Fölster-Holst, R.; Ortonne, J.P.; Potter, P.C.; de Prost, Y.; Davidson, M.J.; Barbier, N.; Goertz, H.P.; Paul, C. J. Am. Acad. Dermatol. 2005, 52, 240-46.
87. Kang, S.; Lucky, A.W.; Pariser, D.; Lawrence, I.; Hanifin, J.M. J. Am.Acad. Dermatol. 2001, 44, S58-64.
88. Hanifin, J.M.; Paller, A.S.; Eichenfield, L.; Clark, R.A.; Korman, N.; Weinstein, G.; Caro, I.; Jaracz, E.; Rico, M.J. J. Am. Acad. Dermatol. 2005, 53, S186-94.
89. Koo, J.Y.M.; Fleischer, A.B.; Abramovits, W.; Pariser, D.M.; McCall, C.O.; Horn, T.D.; Gottlieb, A.B.; Jaracz, E.; Rico, M.J. J. Am. Acad. Dermatol. 2005, 53, S195-205.
90. Jonas, S.; Rayes, N.; Neumann, U.; Neuhaus, R.; Bechstein, W.O.; Guckelberger, O.; Tullius, S.G.; Serke, S.; Neuhaus, P. Cancer 1997, 80, 1141-50.
91. Bieber, T.; Cork, M.; Ellis, C.; Girolomoni, G.; Groves, R.; Langley, R.; Luger, T.; Meurer, M.; Murrell, D.; Orlow, S.; Paller, A.; de Prost, Y.; Puig, L.; Ring, J.; Saurat, J.H.; Schwartz, T.; Shear, N.; Sting, G.; Taieb, A.; Therstup-Pedersen, K. Dermatology 2005, 211, 77-78.
92. Berger, T.G.; Duvic, M.; Van Voorhees, A.S.; Frieden, I.J. J. Am. Acad. Dermatol. 2006, 54, 818-28.
93. Langeland, T.; Engh, V. Br. J. Dermatol. 2005, 152, 183-85.
94. Bunker, C.B.; Neill, S.; Staughton, R.C. Arch. Dermatol. 2004, 140, 1169.
95. Niwa, Y.; Terashima, T.; Sumi, H. Br. J. Dermatol. 2003, 149, 960-67.
96. Hickey, J.R.; Robson, A.; Barker, J.N.; Smith, C.H. Br. J. Dermatol. 2005, 152, 152-54.
97. Fonacier, L.; Charlesworth, E.N.; Spergel, J.M.; Leung, D.Y. Ann. Allergy Asthma Immunol. 2006, 97, 117-120.
98. Spergel, J.M.; Leung, D.Y. Curr. Allergy Asthma Rep. 2006, 6, 270-274.
99. Fleischer, A.B. Dermatol. Online. J. 2006, 12, 2.
100. Wellington, K.; Noble, S. Am. J. Clin. Dermatol. 2004, 5, 479-95.
101. Abramovitz, W.; Hung, P.; Tong, K.B. Am. J. Clin. Dermatol. 2006, 7, 213-22.