Tacrolimus ointment 0.03% shows efficacy and safety in pediatric and adult patients with mild to moderate atopic dermatitis

Journal of the American Academy of Dermatology

Volumn 53, Issue 2 SUPPL. 2, 2005, Pages

  Chapman, M Shane ^a   Schachner, Lawrence A ^b   Breneman, Debra ^c   Boguniewicz, Mark ^d   Gold, Michael H ^e   Shull, Toni ^f   Linowski, Gregory J ^f   Jaracz, Eileen ^f  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^e GOLD SKIN CARE CENTER   (United States)

^f ASTELLAS PHARMA GLOBAL DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TACROLIMUS;

ACNE; ADOLESCENT; ADULT; AGED; ARTICLE; ATOPIC DERMATITIS; BURNING SENSATION; CHILD; DRUG EFFICACY; DRUG SAFETY; ERYTHEMA; FEMALE; FOLLICULITIS; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; MALE; OINTMENT; PAIN; PRIORITY JOURNAL; PRURITUS; RATING SCALE; STINGING SENSATION; TREATMENT OUTCOME; VERRUCA VULGARIS; VIRAL SKIN DISEASE;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; DERMATITIS, ATOPIC; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; MALE; MIDDLE AGED; OINTMENTS; RANDOMIZED CONTROLLED TRIALS; TACROLIMUS; TREATMENT OUTCOME;

EID: 18144409596     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2005.04.061     Document Type: Article

References (15)

1. K.L. Goa Clinical pharmacology and pharmacokinetic properties of topically applied corticosteroids: a review Drugs 36 1988 51 61
2. M. Mori, N. Pimpinelli, and B. Giannotti Topical corticosteroids and unwanted local effects: improving the benefit/risk ratio Drug Saf 10 1994 406 412
3. S. Reitamo, A. Wollenberg, E. Schopf, J.L. Perrot, R. Marks, and T. Ruzicka Safety and efficacy of tacrolimus ointment monotherapy in adults with atopic dermatitis Arch Dermatol 136 2000 999 1006
4. S. Kang, A.W. Lucky, D. Pariser, I. Lawrence, and J.M. Hanifin Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children J Am Acad Dermatol 44 2001 S58 S64
5. A. Paller, L.F. Eichenfield, D.Y.M. Leung, D. Stewart, and M. Appell A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients J Am Acad Dermatol 44 2001 S47 S57
6. T. Ruzicka, T. Bieber, E. Schopf, A. Rubins, A. Dobozy, J.D. Bos for the European Tacrolimus Multicenter Atopic Dermatitis Study Group A short-term trial of tacrolimus ointment for atopic dermatitis N Engl J Med 337 1997 816 821
7. J.M. Hanifin, M.R. Ling, R. Langley, D. Breneman, and E. Rafal Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I, efficacy J Am Acad Dermatol 44 2001 S28 S38
8. N.A. Soter, A.B. Fleischer Jr., G.F. Webster, E. Monroe, and I. Lawrence Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part II, safety J Am Acad Dermatol 44 2001 S39 S46
9. J.M. Hanifin, and G. Rajka Diagnostic features of atopic dermatitis Acta Derm Venereol Suppl (Stockh) 92 1980 44 47
10. J.M. Hanifin, M. Thurston, M. Omoto, R. Cherill, S.J. Tofte, and M. Graeber The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis Exp Dermatol 10 2001 11 18
11. Schachner LA, Lamerson C, Sheehan MP, Boguniewicz M, Mosser J, Raimer S, et al. Tacrolimus ointment 0.03% is safe and effective for the treatment of mild to moderate atopic dermatitis in pediatric patients: Results from a randomized, double-blind, placebo-controlled study. Pediatrics Electronic Pages (in press). Available at: http://www.pediatrics.aappublications.org. Accessed June 13, 2005.
12. A.B. Fleischer, M. Ling, L. Eichenfield, Y. Satoi, E. Jaracz, and M.J. Rico Tacrolimus ointment for the treatment of atopic dermatitis is not associated with an increase in cutaneous infections J Am Acad Dermatol 47 2002 562 570
13. J.M. Spergel, and A.S. Paller Atopic dermatitis and the atopic march J Allergy Clin Immunol 112 2003 S118 S127
14. L. Drake, M. Prendergast, R. Maher, D. Breneman, N. Korman, and Y. Satoi The impact of tacrolimus ointment on health-related quality of life of adult and pediatric patients with atopic dermatitis J Am Acad Dermatol 44 2001 S65 S72
15. S. Kang, A. Paller, N. Soter, Y. Satoi, M.J. Rico, and J.M. Hanifin Safe treatment of head/neck AD with tacrolimus ointment J Dermatol Treatment 14 2003 86 94