-
1
-
-
14744285958
-
Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells
-
Borys, M. C., D. I. H. Linzer, and E. T. Papoutsakis. 1993. Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells. Bio/ Technology 11: 720-724.
-
(1993)
Bio/ Technology
, vol.11
, pp. 720-724
-
-
Borys, M.C.1
Linzer, D.I.H.2
Papoutsakis, E.T.3
-
2
-
-
10044236577
-
Temperature effects on product-quality-related enzymes in batch CHO cell cultures producing recombinant tPA
-
Clark, K. J. R., F. W. R. Chaplin, and S. W. Harcum. 2004. Temperature effects on product-quality-related enzymes in batch CHO cell cultures producing recombinant tPA. Biotechnol. Prog. 20: 1888-1892.
-
(2004)
Biotechnol. Prog
, vol.20
, pp. 1888-1892
-
-
Clark, K.J.R.1
Chaplin, F.W.R.2
Harcum, S.W.3
-
3
-
-
0035043903
-
Chromosome localization and gene-copy-number quantification of three random integrations in Chinese hamster ovary cells and their amplified cell lines using fluorescence in situ hybridization
-
Davies, J. and M. Reff. 2001. Chromosome localization and gene-copy-number quantification of three random integrations in Chinese hamster ovary cells and their amplified cell lines using fluorescence in situ hybridization. Biotechnol. Appl. Biochem. 33: 99-105.
-
(2001)
Biotechnol. Appl. Biochem
, vol.33
, pp. 99-105
-
-
Davies, J.1
Reff, M.2
-
4
-
-
0021356228
-
Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene
-
Flintoff, W. F., E. Livingston, C. Duff, and R. G. Worton. 1984. Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene. Mol. Cell. Biol. 4: 69-76.
-
(1984)
Mol. Cell. Biol
, vol.4
, pp. 69-76
-
-
Flintoff, W.F.1
Livingston, E.2
Duff, C.3
Worton, R.G.4
-
5
-
-
13544251527
-
Temperature reduction in cultures of hGM-CSF-expressing CHO cells: Effect on productivity and product quality
-
Fogolin, M. B., G. Forno, M. Nimtz, H. S. Conradt, M. Etcheverrigaray, and R. Kratje. 2005. Temperature reduction in cultures of hGM-CSF-expressing CHO cells: Effect on productivity and product quality. Biotechnol. Prog. 21: 17-21.
-
(2005)
Biotechnol. Prog
, vol.21
, pp. 17-21
-
-
Fogolin, M.B.1
Forno, G.2
Nimtz, M.3
Conradt, H.S.4
Etcheverrigaray, M.5
Kratje, R.6
-
6
-
-
0031936814
-
Effect of culture temperature on a recombinant CHO cell line producing a C-terminal α-amidating enzyme
-
Furukawa, K. and K. Ohsuye. 1998. Effect of culture temperature on a recombinant CHO cell line producing a C-terminal α-amidating enzyme. Cytotechnology 26: 153-164.
-
(1998)
Cytotechnology
, vol.26
, pp. 153-164
-
-
Furukawa, K.1
Ohsuye, K.2
-
7
-
-
0032871424
-
Enhancement of productivity of recombinant α-amidating enzyme by low-temperature culture
-
Furukawa, K. and K. Ohsuye. 1999. Enhancement of productivity of recombinant α-amidating enzyme by low-temperature culture. Cytotechnology 31: 85-94.
-
(1999)
Cytotechnology
, vol.31
, pp. 85-94
-
-
Furukawa, K.1
Ohsuye, K.2
-
8
-
-
32344448765
-
Regulation of recombinant monoclonal antibody production in Chinese hamster ovary cells: A comparative study of gene copy number, mRNA level, and protein expression
-
Jiang, Z., Y. Huang, and S. T. Sharfstein. 2006. Regulation of recombinant monoclonal antibody production in Chinese hamster ovary cells: A comparative study of gene copy number, mRNA level, and protein expression. Biotechnol. Prog. 22: 313-318.
-
(2006)
Biotechnol. Prog
, vol.22
, pp. 313-318
-
-
Jiang, Z.1
Huang, Y.2
Sharfstein, S.T.3
-
9
-
-
0033526546
-
Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells
-
Kaufmann, H., X. Mazur, M. Fussenegger, and J. E. Bailey. 1999. Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells. Biotechnol. Bioeng. 63: 573-582.
-
(1999)
Biotechnol. Bioeng
, vol.63
, pp. 573-582
-
-
Kaufmann, H.1
Mazur, X.2
Fussenegger, M.3
Bailey, J.E.4
-
10
-
-
0025684946
-
Use of recombinant DNA technology for engineering mammalian cells to produce proteins
-
Lubiniecki, A. S, ed, Marcel Dekker, New York
-
Kaufman, R. J. 1990. Use of recombinant DNA technology for engineering mammalian cells to produce proteins, pp. 15-69. In Lubiniecki, A. S. (ed.), Large-Scale Mammalian Cell Culture Technology. Marcel Dekker, New York.
-
(1990)
Large-Scale Mammalian Cell Culture Technology
, pp. 15-69
-
-
Kaufman, R.J.1
-
11
-
-
9544246862
-
Decreased chimeric antibody productivity of KR12H-1 transfectoma during long-term culture results from decreased antibody gene copy number
-
Kim, J. H., S. W. Bae, H. J. Hong, and G. M. Lee. 1996. Decreased chimeric antibody productivity of KR12H-1 transfectoma during long-term culture results from decreased antibody gene copy number. Biotechnol. Bioeng. 51: 479-487.
-
(1996)
Biotechnol. Bioeng
, vol.51
, pp. 479-487
-
-
Kim, J.H.1
Bae, S.W.2
Hong, H.J.3
Lee, G.M.4
-
12
-
-
4444343170
-
Enhancement of erythropoietin production from Chinese hamster ovary (CHO) cells by introduction of the urea cycle enzymes, carbamoyl phosphate synthetase 1 and ornithine transcarbamylase
-
Kim, N. Y., Y. J. Lee, H. J. Kim, J. H. Choi, J. K. Kim, K. H. Chang, J. H. Kim, and H. J. Kim. 2004. Enhancement of erythropoietin production from Chinese hamster ovary (CHO) cells by introduction of the urea cycle enzymes, carbamoyl phosphate synthetase 1 and ornithine transcarbamylase. J. Microbiol. Biotechnol. 14: 844-851.
-
(2004)
J. Microbiol. Biotechnol
, vol.14
, pp. 844-851
-
-
Kim, N.Y.1
Lee, Y.J.2
Kim, H.J.3
Choi, J.H.4
Kim, J.K.5
Chang, K.H.6
Kim, J.H.7
Kim, H.J.8
-
13
-
-
0002598959
-
Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure
-
Kim, S. J., N. S. Kim, C. J. Ryu, H. J. Hong, and G. M. Lee. 1998. Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure. Biotechnol. Bioeng. 58: 73-84.
-
(1998)
Biotechnol. Bioeng
, vol.58
, pp. 73-84
-
-
Kim, S.J.1
Kim, N.S.2
Ryu, C.J.3
Hong, H.J.4
Lee, G.M.5
-
14
-
-
18144403564
-
Purification and characterization of recombinant human follicle stimulating hormone produced by Chinese hamster ovary cells
-
Na, K. H., S. C. Kim, K. S. Seo, S. H. Lee, W. B. Kim, and K. C. Choon. 2005. Purification and characterization of recombinant human follicle stimulating hormone produced by Chinese hamster ovary cells. J. Microbiol. Biotechnol. 15: 395-402.
-
(2005)
J. Microbiol. Biotechnol
, vol.15
, pp. 395-402
-
-
Na, K.H.1
Kim, S.C.2
Seo, K.S.3
Lee, S.H.4
Kim, W.B.5
Choon, K.C.6
-
15
-
-
0025397850
-
Chemical decomposition of glutamine in cell culture media: Effect of media type, pH, and serum concentration
-
Ozturk, S. S. and B. O. Palsson. 1990. Chemical decomposition of glutamine in cell culture media: Effect of media type, pH, and serum concentration. Biotechnol. Prog. 6: 121-128.
-
(1990)
Biotechnol. Prog
, vol.6
, pp. 121-128
-
-
Ozturk, S.S.1
Palsson, B.O.2
-
16
-
-
33646751241
-
High-level expression of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cells
-
Park, J. H., S. R. Yu, J. S. Yoon, and K. H. Baek. 2005. High-level expression of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cells. J. Microbiol. Biotechnol. 15: 1397-1401.
-
(2005)
J. Microbiol. Biotechnol
, vol.15
, pp. 1397-1401
-
-
Park, J.H.1
Yu, S.R.2
Yoon, J.S.3
Baek, K.H.4
-
17
-
-
0023839257
-
Evidence that monoclonal antibody production kinetics is related to the integral of viable cells in batch systems
-
Renard, J. M., R. Spagnoli, C. Mazier, M. F. Salles, and E. Mandine. 1988. Evidence that monoclonal antibody production kinetics is related to the integral of viable cells in batch systems. Biotechnol. Lett. 10: 91-96.
-
(1988)
Biotechnol. Lett
, vol.10
, pp. 91-96
-
-
Renard, J.M.1
Spagnoli, R.2
Mazier, C.3
Salles, M.F.4
Mandine, E.5
-
18
-
-
0034607161
-
A high-yielding, generic fed-batch cell culture process for production of recombinant antibodies
-
Sauer, P. W., J. E. Burky, M. C. Wesson, H. D. Sternard, and L. Qu. 2000. A high-yielding, generic fed-batch cell culture process for production of recombinant antibodies. Biotechnol. Bioeng. 67: 585-597.
-
(2000)
Biotechnol. Bioeng
, vol.67
, pp. 585-597
-
-
Sauer, P.W.1
Burky, J.E.2
Wesson, M.C.3
Sternard, H.D.4
Qu, L.5
-
19
-
-
0000409606
-
Spontaneous decomposition of glutamine in cell culture media
-
Tritsch, G. L. and G. E. Moore. 1962. Spontaneous decomposition of glutamine in cell culture media. Exp. Cell. Res. 28: 360-364.
-
(1962)
Exp. Cell. Res
, vol.28
, pp. 360-364
-
-
Tritsch, G.L.1
Moore, G.E.2
-
20
-
-
0031907982
-
Influence of reducing agents on the secretion rate of recombinant erythropoietin from CHO cells
-
Yoon, S. K., Y. H. Ahn, I. C. Kwon, K. Han, and J. Y. Song. 1998. Influence of reducing agents on the secretion rate of recombinant erythropoietin from CHO cells. Biotechnol. Lett. 20: 101-104.
-
(1998)
Biotechnol. Lett
, vol.20
, pp. 101-104
-
-
Yoon, S.K.1
Ahn, Y.H.2
Kwon, I.C.3
Han, K.4
Song, J.Y.5
-
21
-
-
14244265076
-
Effect of culture pH on erythropoietin production by Chinese hamster ovary cells grown in suspension at 32.5 and 37.0°C
-
Yoon, S. K., S. L. Choi, J. Y. Song, and G. M. Lee. 2005. Effect of culture pH on erythropoietin production by Chinese hamster ovary cells grown in suspension at 32.5 and 37.0°C. Biotechnol. Bioeng. 22: 345-356.
-
(2005)
Biotechnol. Bioeng
, vol.22
, pp. 345-356
-
-
Yoon, S.K.1
Choi, S.L.2
Song, J.Y.3
Lee, G.M.4
-
22
-
-
10044226092
-
Enhancing effect of low culture temperature on specific antibody productivity of recombinant Chinese hamster ovary cells: Clonal variation
-
Yoon, S. K., S. L. Choi, J. Y. Song, and G. M. Lee. 2004. Enhancing effect of low culture temperature on specific antibody productivity of recombinant Chinese hamster ovary cells: Clonal variation. Biotechnol. Prog. 20: 1683-1688.
-
(2004)
Biotechnol. Prog
, vol.20
, pp. 1683-1688
-
-
Yoon, S.K.1
Choi, S.L.2
Song, J.Y.3
Lee, G.M.4
|