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Volumn 74, Issue 2, 2007, Pages 298-308

The anti-inflammatory actions of LCY-2-CHO, a carbazole analogue, in vascular smooth muscle cells

Author keywords

Anti inflammation; Cell signaling; HO 1; LCY 2 CHO; Vascular smooth muscle

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 9 (2 CHLOROBENZYL) 9H CARBAZOLE 3 CARBALDEHYDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CARBAZOLE DERIVATIVE; CYCLOOXYGENASE 2; HEME OXYGENASE 1; I KAPPA B ALPHA; I KAPPA B KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 34249983852     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.04.008     Document Type: Article
Times cited : (46)

References (46)
  • 1
    • 4243550127 scopus 로고    scopus 로고
    • Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance
    • Ryter S.W., Otterbein L.E., Morse D., and Choi A.M. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem 234-235 (2002) 249-263
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 249-263
    • Ryter, S.W.1    Otterbein, L.E.2    Morse, D.3    Choi, A.M.4
  • 2
    • 0022632224 scopus 로고
    • Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible
    • Maines M.D., Trakshel G.M., and Kutty R.K. Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 261 (1986) 411-419
    • (1986) J Biol Chem , vol.261 , pp. 411-419
    • Maines, M.D.1    Trakshel, G.M.2    Kutty, R.K.3
  • 3
    • 0023731036 scopus 로고
    • Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications
    • Maines M.D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2 (1988) 2557-2568
    • (1988) FASEB J , vol.2 , pp. 2557-2568
    • Maines, M.D.1
  • 4
    • 8544246393 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3
    • McCoubrey Jr. W.K., Huang T.J., and Maines M.D. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247 (1997) 725-732
    • (1997) Eur J Biochem , vol.247 , pp. 725-732
    • McCoubrey Jr., W.K.1    Huang, T.J.2    Maines, M.D.3
  • 5
    • 3042799349 scopus 로고    scopus 로고
    • Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene
    • Hayashi S., Omata Y., Sakamoto H., Higashimoto Y., Hara T., Sagara Y., et al. Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene. Gene 336 (2004) 241-250
    • (2004) Gene , vol.336 , pp. 241-250
    • Hayashi, S.1    Omata, Y.2    Sakamoto, H.3    Higashimoto, Y.4    Hara, T.5    Sagara, Y.6
  • 6
    • 0030961521 scopus 로고    scopus 로고
    • Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells
    • Durante W., Kroll M.H., Christodoulides N., Peyton K.J., and Schafer A.I. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ Res 80 (1997) 557-564
    • (1997) Circ Res , vol.80 , pp. 557-564
    • Durante, W.1    Kroll, M.H.2    Christodoulides, N.3    Peyton, K.J.4    Schafer, A.I.5
  • 7
    • 0035203965 scopus 로고    scopus 로고
    • Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells
    • Tian W., Bonkovsky H.L., Shibahara S., and Cohen D.M. Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells. Am J Physiol Renal Physiol 281 (2001) F983-F991
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Tian, W.1    Bonkovsky, H.L.2    Shibahara, S.3    Cohen, D.M.4
  • 8
    • 12544253089 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle
    • Liu X.M., Peyton K.J., Ensenat D., Wang H., Schafer A.I., Alam J., et al. Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. J Biol Chem 280 (2005) 872-877
    • (2005) J Biol Chem , vol.280 , pp. 872-877
    • Liu, X.M.1    Peyton, K.J.2    Ensenat, D.3    Wang, H.4    Schafer, A.I.5    Alam, J.6
  • 10
    • 0035750333 scopus 로고    scopus 로고
    • Heme oxygenase as an intrinsic defense system in vascular wall: implication against atherogenesis
    • Ishikawa K., and Maruyama Y. Heme oxygenase as an intrinsic defense system in vascular wall: implication against atherogenesis. J Atheroscler Thromb 8 (2001) 63-70
    • (2001) J Atheroscler Thromb , vol.8 , pp. 63-70
    • Ishikawa, K.1    Maruyama, Y.2
  • 11
    • 0035949615 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice
    • Juan S.H., Lee T.S., Tseng K.W., Liou J.Y., Shyue S.K., Wu K.K., et al. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation 104 (2001) 1519-1525
    • (2001) Circulation , vol.104 , pp. 1519-1525
    • Juan, S.H.1    Lee, T.S.2    Tseng, K.W.3    Liou, J.Y.4    Shyue, S.K.5    Wu, K.K.6
  • 12
    • 0038745911 scopus 로고    scopus 로고
    • Heme oxygenase-1 in growth control and its clinical application to vascular disease
    • Durante W. Heme oxygenase-1 in growth control and its clinical application to vascular disease. J Cell Physiol 195 (2003) 373-382
    • (2003) J Cell Physiol , vol.195 , pp. 373-382
    • Durante, W.1
  • 13
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodelling
    • Yet S.F., Layne M.D., Liu X., Chen Y.H., Ith B., Sibinga N.E., et al. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodelling. FASEB J 17 (2003) 1759-1761
    • (2003) FASEB J , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibinga, N.E.6
  • 14
    • 0034668216 scopus 로고    scopus 로고
    • Gene regulation of heme oxygenase-1 as a therapeutic target
    • Immenschuh S., and Ramadori G. Gene regulation of heme oxygenase-1 as a therapeutic target. Biochem Pharmacol 60 (2000) 1121-1128
    • (2000) Biochem Pharmacol , vol.60 , pp. 1121-1128
    • Immenschuh, S.1    Ramadori, G.2
  • 15
    • 0036784051 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury
    • Zhang X., Bedard E.L., Potter R., Zhong R., Alam J., Choi A.M., et al. Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury. Am J Physiol Lung Cell Mol Physiol 283 (2002) L815-L819
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.283
    • Zhang, X.1    Bedard, E.L.2    Potter, R.3    Zhong, R.4    Alam, J.5    Choi, A.M.6
  • 16
    • 1542335553 scopus 로고    scopus 로고
    • Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
    • Martin D., Rojo A.I., Salinas M., Diaz R., Gallardo G., Alam J., et al. Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J Biol Chem 279 (2004) 8919-8929
    • (2004) J Biol Chem , vol.279 , pp. 8919-8929
    • Martin, D.1    Rojo, A.I.2    Salinas, M.3    Diaz, R.4    Gallardo, G.5    Alam, J.6
  • 17
    • 0036400691 scopus 로고    scopus 로고
    • Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite
    • Gong P., Stewart D., Hu B., Vinson C., and Alam J. Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite. Arch Biochem Biophys 405 (2002) 265-274
    • (2002) Arch Biochem Biophys , vol.405 , pp. 265-274
    • Gong, P.1    Stewart, D.2    Hu, B.3    Vinson, C.4    Alam, J.5
  • 18
    • 0034623211 scopus 로고    scopus 로고
    • Mechanisms of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
    • Alam J., Wicks C., Steward D., Gong P., Touchard C., Otterbein S., et al. Mechanisms of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J Biol Chem 275 (2000) 27694-27702
    • (2000) J Biol Chem , vol.275 , pp. 27694-27702
    • Alam, J.1    Wicks, C.2    Steward, D.3    Gong, P.4    Touchard, C.5    Otterbein, S.6
  • 20
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13 (1999) 76-86
    • (1999) Genes Dev , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6
  • 21
    • 0037569694 scopus 로고    scopus 로고
    • Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
    • Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., et al. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem J 371 (2003) 887-895
    • (2003) Biochem J , vol.371 , pp. 887-895
    • Balogun, E.1    Hoque, M.2    Gong, P.3    Killeen, E.4    Green, C.J.5    Foresti, R.6
  • 22
    • 3042752557 scopus 로고    scopus 로고
    • Nrf2-dependent gene expressions: a molecular toxicological aspect
    • Numazawa S., and Yoshida T. Nrf2-dependent gene expressions: a molecular toxicological aspect. J Toxicol Sci 29 (2004) 81-89
    • (2004) J Toxicol Sci , vol.29 , pp. 81-89
    • Numazawa, S.1    Yoshida, T.2
  • 23
    • 33745986025 scopus 로고    scopus 로고
    • Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein
    • Wu C.C., Hsieh C.W., Lai P.H., Lin J.B., Liu Y.C., and Wung B.S. Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein. Toxicol Appl Pharmacol 214 (2006) 244-252
    • (2006) Toxicol Appl Pharmacol , vol.214 , pp. 244-252
    • Wu, C.C.1    Hsieh, C.W.2    Lai, P.H.3    Lin, J.B.4    Liu, Y.C.5    Wung, B.S.6
  • 24
    • 33646179260 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways
    • Wu C.C., Hsu M.C., Hsieh C.W., Lin J.B., Lai P.H., and Wung B.S. Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci 78 (2006) 2889-2897
    • (2006) Life Sci , vol.78 , pp. 2889-2897
    • Wu, C.C.1    Hsu, M.C.2    Hsieh, C.W.3    Lin, J.B.4    Lai, P.H.5    Wung, B.S.6
  • 25
    • 0036262676 scopus 로고    scopus 로고
    • Anti-inflammatory activity of 9-substituted benzyl-3-substituted carbazole derivatives
    • Lee C.Y., Huang L.J., Wang J.P., and Kuo S.C. Anti-inflammatory activity of 9-substituted benzyl-3-substituted carbazole derivatives. Chin Pharm J 54 (2002) 35-40
    • (2002) Chin Pharm J , vol.54 , pp. 35-40
    • Lee, C.Y.1    Huang, L.J.2    Wang, J.P.3    Kuo, S.C.4
  • 26
    • 0036259230 scopus 로고    scopus 로고
    • Synthesis and antiplatelet activity of 9-benzyl-3-hydroxymethylcarbazoles
    • Lee C.Y., Kuo S.C., Teng C.M., and Huang L.J. Synthesis and antiplatelet activity of 9-benzyl-3-hydroxymethylcarbazoles. Chin Pharm J 54 (2002) 25-34
    • (2002) Chin Pharm J , vol.54 , pp. 25-34
    • Lee, C.Y.1    Kuo, S.C.2    Teng, C.M.3    Huang, L.J.4
  • 27
    • 0036609017 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages by a synthetic carbazole, LCY-2-CHO
    • Tsao L.T., Lee C.Y., Huang L.J., Kuo S.C., and Wang J.P. Inhibition of lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages by a synthetic carbazole, LCY-2-CHO. Biochem Pharmacol 63 (2002) 1961-1968
    • (2002) Biochem Pharmacol , vol.63 , pp. 1961-1968
    • Tsao, L.T.1    Lee, C.Y.2    Huang, L.J.3    Kuo, S.C.4    Wang, J.P.5
  • 28
    • 1942472468 scopus 로고    scopus 로고
    • The anti-inflammatory carbazole, LCY-2-CHO, inhibits lipopolysaccharide-induced inflammatory mediator expression through inhibition of the p38 mitogen-activated protein kinase signaling pathway in macrophages
    • Ho F.M., Lai C.C., Huang L.J., Kuo T.C., Chao C.M., and Lin W.W. The anti-inflammatory carbazole, LCY-2-CHO, inhibits lipopolysaccharide-induced inflammatory mediator expression through inhibition of the p38 mitogen-activated protein kinase signaling pathway in macrophages. Br J Pharmacol 141 (2004) 1037-1047
    • (2004) Br J Pharmacol , vol.141 , pp. 1037-1047
    • Ho, F.M.1    Lai, C.C.2    Huang, L.J.3    Kuo, T.C.4    Chao, C.M.5    Lin, W.W.6
  • 29
    • 0042388672 scopus 로고    scopus 로고
    • Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases
    • Boo Y.C., and Jo H. Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am J Physiol Cell Physiol 285 (2003) C499-C508
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Boo, Y.C.1    Jo, H.2
  • 30
    • 0033566274 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors
    • Hara E., Takahashi K., Takeda K., Nakayama M., Yoshizawa M., Fujita H., et al. Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. Biochem Pharmacol 58 (1999) 227-236
    • (1999) Biochem Pharmacol , vol.58 , pp. 227-236
    • Hara, E.1    Takahashi, K.2    Takeda, K.3    Nakayama, M.4    Yoshizawa, M.5    Fujita, H.6
  • 31
    • 0034607632 scopus 로고    scopus 로고
    • Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols
    • Motterlini R., Foresti R., Bassi R., Calabrese V., Clark J.E., and Green C.J. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J Biol Chem 275 (2000) 13613-13620
    • (2000) J Biol Chem , vol.275 , pp. 13613-13620
    • Motterlini, R.1    Foresti, R.2    Bassi, R.3    Calabrese, V.4    Clark, J.E.5    Green, C.J.6
  • 32
    • 0037767747 scopus 로고    scopus 로고
    • Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium
    • Buckley B.J., Marshall Z.M., and Whorton A.R. Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium. Biochem Biophys Res Commun 307 (2003) 973-979
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 973-979
    • Buckley, B.J.1    Marshall, Z.M.2    Whorton, A.R.3
  • 33
    • 27744598777 scopus 로고    scopus 로고
    • NO signaling in ARE-mediated gene expression
    • Park E.Y., and Kim S.G. NO signaling in ARE-mediated gene expression. Methods Enzymol 396 (2005) 341-349
    • (2005) Methods Enzymol , vol.396 , pp. 341-349
    • Park, E.Y.1    Kim, S.G.2
  • 34
    • 0032915909 scopus 로고    scopus 로고
    • Distribution and prevalence of inducible nitric oxide synthase in atherosclerotic vessels of long-term cholesterol-fed rabbits
    • Behr D., Rupin A., Fabiani J.N., and Verbeuren T.J. Distribution and prevalence of inducible nitric oxide synthase in atherosclerotic vessels of long-term cholesterol-fed rabbits. Atherosclerosis 142 (1999) 335-344
    • (1999) Atherosclerosis , vol.142 , pp. 335-344
    • Behr, D.1    Rupin, A.2    Fabiani, J.N.3    Verbeuren, T.J.4
  • 36
    • 0035571606 scopus 로고    scopus 로고
    • Immune mechanisms in atherosclerosis
    • Hansson G.K. Immune mechanisms in atherosclerosis. Atheroscler Thromb Vasc Biol 21 (2001) 1876-1890
    • (2001) Atheroscler Thromb Vasc Biol , vol.21 , pp. 1876-1890
    • Hansson, G.K.1
  • 37
    • 33645456200 scopus 로고    scopus 로고
    • Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression
    • Boisvert W.A., Rose D.M., Johnson K.A., Fuentes M.E., Lira S.A., Curtiss L.K., et al. Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression. Am J Pathol 168 (2006) 1385-1395
    • (2006) Am J Pathol , vol.168 , pp. 1385-1395
    • Boisvert, W.A.1    Rose, D.M.2    Johnson, K.A.3    Fuentes, M.E.4    Lira, S.A.5    Curtiss, L.K.6
  • 38
    • 0032972299 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase in macrophages and smooth muscle cells in various types of human atherosclerotic lesions
    • Luoma J.S., and Ylä-Herttuala S. Expression of inducible nitric oxide synthase in macrophages and smooth muscle cells in various types of human atherosclerotic lesions. Virchows Arch 434 (1999) 561-568
    • (1999) Virchows Arch , vol.434 , pp. 561-568
    • Luoma, J.S.1    Ylä-Herttuala, S.2
  • 39
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: the control of NF-κB activity
    • Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu Rev Immunol 18 (2000) 621-663
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 42
    • 22844450096 scopus 로고    scopus 로고
    • Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
    • Hosoya T., Maruyama A., Kang M.I., Kawatani Y., Shibata T., Uchida K., et al. Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. J Biol Chem 280 (2005) 27244-27250
    • (2005) J Biol Chem , vol.280 , pp. 27244-27250
    • Hosoya, T.1    Maruyama, A.2    Kang, M.I.3    Kawatani, Y.4    Shibata, T.5    Uchida, K.6
  • 43
    • 33646418968 scopus 로고    scopus 로고
    • Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression
    • Chen X.L., Dodd G., Thomas S., Zhang X., Wasserman M.A., Rovin B.H., et al. Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression. Am J Physiol Heart Circ Physiol 290 (2006) H1862-H1870
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Chen, X.L.1    Dodd, G.2    Thomas, S.3    Zhang, X.4    Wasserman, M.A.5    Rovin, B.H.6
  • 44
    • 0037667901 scopus 로고    scopus 로고
    • Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents
    • Sherratt P.J., McLellan L.I., and Hayes J.D. Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents. Biochem Pharmacol 66 (2003) 51-61
    • (2003) Biochem Pharmacol , vol.66 , pp. 51-61
    • Sherratt, P.J.1    McLellan, L.I.2    Hayes, J.D.3
  • 45
    • 27944437786 scopus 로고    scopus 로고
    • Activation of the Nrf2/antioxidant response pathway increases IL-8 expression
    • Zhang X., Chen X., Song H., Chen H.Z., and Rovin B.H. Activation of the Nrf2/antioxidant response pathway increases IL-8 expression. Eur J Immunol 35 (2005) 3258-3267
    • (2005) Eur J Immunol , vol.35 , pp. 3258-3267
    • Zhang, X.1    Chen, X.2    Song, H.3    Chen, H.Z.4    Rovin, B.H.5
  • 46
    • 21944452087 scopus 로고    scopus 로고
    • Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1
    • Yang H., Magilnick N., Lee C., Kalmaz D., Ou X., Chan J.Y., et al. Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1. Mol Cell Biol 25 (2005) 5933-5946
    • (2005) Mol Cell Biol , vol.25 , pp. 5933-5946
    • Yang, H.1    Magilnick, N.2    Lee, C.3    Kalmaz, D.4    Ou, X.5    Chan, J.Y.6


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