Distribution and prevalence of inducible nitric oxide synthase in atherosclerotic vessels of long-term cholesterol-fed rabbits

Atherosclerosis

Volumn 142, Issue 2, 1999, Pages 335-344

  Behr, Delphine ^a   Rupin, Alain ^b   Fabiani, Jean Noël ^a   Verbeuren, Tony J ^b  

^a Dept Cardiovasc Surg Lab d'E Hop Broussais 16 Rue Didot 75014 ^*  (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Atherosclerosis; Macrophages; Nitric oxide; Nitric oxide synthase; Smooth muscle cells

Indexed keywords

NITRIC OXIDE SYNTHASE;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LOCALIZATION; HYPERCHOLESTEROLEMIA; INTIMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; RABBIT; THORACIC AORTA;

EID: 0032915909     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(98)00254-8     Document Type: Article

References (58)

1. Harrison D.G. Alterations of vasomotor regulation in atherosclerosis. Cardiovasc. Drugs. Ther. 9:1995;55-63.
2. Verbeuren TJ, Jordaens FH, Zonnekeyn LL, Van Hove CE, Coene M-C, Herman AG. Effect of hypercholesterolemia and vascular reactivity in the rabbit: endothelium-dependent and endothelium-independant contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits. Circ Res 1986;58:552-564.
3. Verbeuren T.J., Jordaens F.H., Van Hove C.E., Van Hoydonck A.E., Herman A.G. Release and vascular activity of endothelium derived relaxing factor in atherosclerotic rabbit aorta. Eur. J. Pharmacol. 191:1990;173-184.
4. Kolodgie F., Virmani R., Rice H., Mergner W. Vascular reactivity during the progression of atherosclerotic plaque. Circ. Res. 66:1990;1112-1126.
5. Verbeuren T.J. Endothelium and coronary atherosclerosis. Cor. Art. Dis. 2:1991;323-337.
6. Simonet S., Bailliencourt J.P.D., Descombes J.J., Mennecier P., Laubie M., Verbeuren T.J. Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta: implication of reduced nitric oxide and cGMP production. Circ. Res. 72:1993;616-630.
7. Verbeuren T.J., Bonhomme E., Laubie M., Simonet S. Evidence for induction of non endothelial NO Synthase in aortas of cholesterol-fed rabbits. J. Cardiovasc. Pharmacol. 21:1993;841-845.
8. Esaki T., Hayashi T., Muto E., Yamada K., Kuzya M., Iguchi A. Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits. Atherosclerosis. 128:1997;39-46.
9. Buttery L., Springall D., Chester A. et al. Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab. Invest. 75:1996;77-85.
10. Minor R.L., Myers P.R., Guerra R., Bates J.N., Harrison D.G. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. J. Clin. Invest. 86:1990;2109-2116.
11. Rupin A., Behr D., Verbeuren T.J. Increased activity of guanylate cyclase in the atherosclerotic rabbit aorta: role of non-endothelial nitric oxide synthases. Br. J. Pharmacol. 119:1996;1233-1238.
12. Nakumara M., Abe S., Kinukawa N. Causal relationship between occlusive lesions of the coronary artery and myocardial fibrosis in arteriosclerotic rabbits-differences between cholesterol-fed and heritable hyperlipidemic rabbits. Atherosclerosis. 124:1996;37-47.
13. Kolodgie F. Jr., Largis E., Wrenn S. et al. Hypercholesterolemia in the rabbit induced by feeding graded amounts of low-level cholesterol: methodological considerations regarding individual variability in response to dietary cholesterol and developement of lesion type. Arterioscler. Thromb. Vasc. Biol. 16:1996;1454-1464.
14. Spagnoli LG, Orlandi A, Mauriello A, Santeusanio G, Angelis Cd, Lucreziotti R, Ramacci MT. Aging and atherosclerosis in the rabbit: 1 distribution prevalence and morphology of atherosclerotic lesions. Atherosclerosis 1991;89:11-24.
15. Rosenfeld R., Ross R. Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis. 10:1990;680-687.
16. Tsukada T., Rosenfeld M., Ross R., Gown A.M. Immunocytochemical analysis of cellular components in atherosclerotic lesions: use of monoclonal antibodies with the Watanabe and fat-fed rabbit. Arteriosclerosis. 6:1986;60-1613.
17. Kittelberger R., Davis P.F., Stehbens W.E. An improved immunofluorescence technique for the histological examination of blood vessel tissue. Acta. Histochem. 86:1989;137-142.
18. Sokal R, Rohlf F editors. Biometry, 2nd edition. WH Freeman and company, 1981.
19. Mugge A., Brandes R.P., Boger R.H. et al. Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits. J. Cardiovasc. Pharmacol. 24:1994;994-998.
20. Radi R., Beckmann J., Bush K., Freeman B. Peroxynitrite-induced membrane lipid peroxydation: the cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288:1991;481-487.
21. Ohara Y., Peterson T.E., Harrison D.G. Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 91:1993;2546-2551.
22. Beckmann J., Beckmann T., Chen J., Marshall P., Freeman B. Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA. 87:1990;1620-1624.
23. Okano M., Yoshida Y. Endothelial cell morphometry of atherosclerotic lesions and flow profiles at aortic bifurcations in cholesterol-fed rabbits. J. Biomech. Eng. 114:1992;301-308.
24. Babaev V., Bobryshev Y., Stenina O., Tararak A., Gabbiani G. Heterogeneity of smooth muscle cells in atheromatous plaque of human aorta. Am. J. Pathol. 136:1990;1031-1042.
25. Najibi S., Cowan C., Palacino J., Cohen R. Enhanced role of potassium channels in relaxations to acetylcholine in hypercholesterolemic rabbit carotid artery. Am. J. Physiol. 266:1994;H2061-2067.
26. Cohen R., Plane F., Najibi S., Huk I., Malinski T., Garland C. Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery. Proc. Natl. Acad. Sci. USA. 94:1997;4193-4198.
27. Hansson G., Seifert P., Olsson G., Bondjers G. Immunohistochemical detection of macrophages and T lymphocytes in atherosclerotic lesions of cholesterol-fed rabbits. Arterioscler. Thromb. 11:1991;745-750.
28. Ball R.Y., Stowers E.C., Burton J.H., Cary N.R.B., Skepper J.N., Mitchinson M.J. Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. Atherosclerosis. 114:1995;45-54.
29. Xie Q-W, Cho H, Mumford R, Swiderek K, Lee T, Ding A, Troso T, Nathan C. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992;256:225-228.
30. Lyons C., Orloff G., Cunningham J. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267:1992;6370-6374.
31. Wildhirt S., Dudek R., Suzuki H., Pinto V., Narayan K., Bing R. Immunohistochemistry in the identification of NOS isoenzymes in myocardial infarction. Cardiovasc. Res. 29:1995;526-531.
32. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-809.
33. Stary H.C., Chandler A.B., Glacov S. et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis: a report from the committee on vascular lesions of the council on arteriosclerosis, AHA. Arterioscler. Thromb. 14:1994;840-856.
34. Tipping P., Hancock W. Production of tumor necrosis factor and interleukin-1 by macrophages from human atheromatous plaques. Am. J. Pathol. 142:1993;1721-1728.
35. Barath P., Fisherlein M., Cao J., Berenson J., Helfant R., Forrester J. Detection and localization of tumor necrosis factor in human atheroma. Am. J. Cardiol. 65:1990;297-302.
36. Oemar B., Yang Z., Luscher T. Molecular and cellular mechanisms of atherosclerosis. Curr. Opin. Nephrol. Hypertens. 4:1995;82-91.
37. Nilsson J. Cytokines and smooth muscle cells in atherosclerosis. Cardiovascular. Res. 27:1993;1184-1190.
38. Nomoto A., Mutoh S., Hagihara H., Yamaguchi I. Smooth muscle cell migration induced by inflammatory cell products and its inhibition by a potent calcium antagonist nilvadipine. Atherosclerosis. 72:1988;213-219.
39. Busse R., Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS. Lett. 275:1990;87-90.
40. Beasley D., Eldrige M. Interleukin-1 β and tumor necrosis factor-α synergistically induce NO synthase in rat vascular smooth muscle cells. Am. J. Physiol. 266:1994;1197-1203.
41. Jorens P., Matthys K., Bult H. Modulation of nitric oxide synthase activity in macrophages. Mediators. Inflamm. 4:1995;75-89.
42. Forstermann U., Closs E.I., Pollock J.S. et al. Nitric oxide synthase isoenzymes: characterization, purification, molecular cloning, and functions. Hypertension. 23:1994;1121-1131.
43. Aliev G, Burnstock G. Distribution of constitutive and inducible NOS and ET-1 immunoreactivity in thoracic aortic endothelium in Watanabe Heritall Hyperlipidemic (WHHL) rabbits. Atherosclerosis l995;115:61.
44. Candipan R, Wang B-Y, Buitrago R, Tsao P, Cooke J. Regression or progression: dependency on vascular nitric oxide. Arterioscler Thromb Vasc Biol 1996;16:44-50.
45. Radomski M., Palmer R., Moncada S. Characterization of the L-Arginine-nitric oxide pathway in human platelets. Br. J. Pharmacol. 101:1990;325-328.
46. Kubes P., Suzuki M., Granger D. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA. 88:1991;4651-4655.
47. Joris I., Nunnari J., Krolikowsi F., Majno G. Studies on the pathogenesis of atherosclerosis: I adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats. Am. J. Pathol. 113:1983;341-358.
48. Yates M., Lambert L., Whitten J.P. A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages. FEBS. Lett. 309:1992;135-138.
49. Hogg N, Kalyanaraman B, Joseph J, Struck A, Parthasarathy S. Inhibition of low density lipoprotein oxidation by nitric oxide: potential role in atherogenesis. FEBS Lett 1993;334.
50. Boger R., Bode-Boger S., Mugge A. Supplementation of hypercholesterolaemic rabbits with L-Arginine reduces the vascular release of superoxide anions and restores NO production. Atherosclerosis. 117:1995;273-284.
51. Clancy R., Leszczynska-Piziak J., Abramson S. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J. Clin. Invest. 90:1992;1116-1121.
52. Steinke W., Els T., Hennerici M. Compensatory carotid artery dilatation in early atherosclerosis. Circulation. 89:1994;2578-2581.
53. Nakaki T., Nakayama M., Kato R. Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells. Eur. J. Pharmacol. 189:1990;347-353.
54. Garg U., Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. invest. 83:1989;1774-1777.
55. Trachtman H., Futterweit S., Singhal P. Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesengial cells. Biochem. Biophys. Res. Commun. 207:1995;120-125.
56. Naruse K., Shimizu K., Muramatsu M. et al. Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta. Arterioscler. Thromb. 14:1994;746-752.
57. Cayatte A.S., Palacino J.J., Horten K., Cohen R.A. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler. Thromb. 14:1994;753-759.
58. Beckmann J., Ye Y., Anderson P. et al. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol. Chem. Hoppe-Seyler. 375:1994;81-88.