Construction and characterization of a full-length infectious simian T-cell lymphotropic virus type 3 molecular clone

Journal of Virology

Volumn 81, Issue 12, 2007, Pages 6276-6285

  Chevalier, Sébastien Alain ^a   Walic, Marine ^a   Calattini, Sara ^a   Mallet, Adeline ^a   Prévost, Marie Christine ^a   Gessain, Antoine ^a   Mahieux, Renaud ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN P24; GAG PROTEIN; GREEN FLUORESCENT PROTEIN; PROTEIN P19; REX PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 2; IMMUNOFLUORESCENCE; LONG TERMINAL REPEAT; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVIRUS; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIMIAN T CELL LYMPHOTROPIC VIRUS 3; SYNCYTIUM; TAX GENE; VIRION; VIRUS CHARACTERIZATION; VIRUS GENE; VIRUS PATHOGENESIS; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, VIRAL; GREEN FLUORESCENT PROTEINS; HAPLORHINI; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; PRIMATE T-LYMPHOTROPIC VIRUS 3; RNA, VIRAL; VIRAL ENVELOPE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 2; SIMIAN IMMUNODEFICIENCY VIRUS - AGM; SIMIAN T-LYMPHOTROPIC VIRUS 3;

EID: 34249949269     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02538-06     Document Type: Article

References (68)

1. 1 is required for efficient viral infectivity in primary lymphocytes. J. Virol. 74:9828-9835.
2. Albrecht, B., and M. D. Lairmore. 2002. Critical role of human T-lymphotropic virus type 1 accessory proteins in viral replication and pathogenesis. Microbiol. Mol. Biol. Rev. 66:396-406.
3. Anderson, M., and P. L. Green. 2005. Growth and manipulation of a human T-cell leukemia virus type 2 full-length molecular clone. Methods Mol. Biol. 304:409-421.
4. Arnold, J., B. Yamamoto, M. Li, A. J. Phipps, I. Younis, M. D. Lairmore, and P. L. Green. 2006. Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1. Blood 107:3976-3982.
5. Bartoe, J. T., B. Albrecht, N. D. Collins, M. D. Robek, L. Ratner, P. L. Green, and M. D. Lairmore. 2000. Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo. J. Virol. 74:1094-1100.
6. Calattini, S., S. A. Chevalier, R. Duprez, P. Afonso, A. Froment, A. Gessain, and R. Mahieux. 2006. Human T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human Tax3 protein. J. Virol. 80:9876-9888.
7. Calattini, S., S. A. Chevalier, R. Duprez, S. Bassot, A. Froment, R. Mahieux, and A. Gessain. 2005. Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa. Retrovirology 2:30.
8. Ceccaldi, P. E., F. Delebecque, M. C. Prevost, A. Moris, J. P. Abastado, A. Gessain, O. Schwartz, and S. Ozden. 2006. DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells. J. Virol. 80:4771-1780.
9. Chen, I. S., J. McLaughlin, J. C. Gasson, S. C. Clark, and D. W. Golde. 1983. Molecular characterization of genome of a novel human T-cell leukaemia virus. Nature 305:502-505.
10. Chevalier, S. A., L. Meertens, S. Calattini, A. Gessain, L. Kiemer, and R. Mahieux. 2005. Presence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein. Retrovirology 2:70.
11. Chevalier, S. A., L. Meertens, C. Pise-Masison, S. Calattini, H. Park, A. A. Alhaj, M. Zhou, A. Gessain, F. Kashanchi, J. N. Brady, and R. Mahieux. 2006. The tax protein from the primate T-cell lymphotropic virus type 3 is expressed in vivo and is functionally related to HTLV-1 Tax rather than HTLV-2 Tax. Oncogene 25:4470-4482.
12. Ciminale, V., G. N. Pavlakis, D. Derse, C. P. Cunningham, and B. K. Felber. 1992. Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type 1. J. Virol. 66:1737-1745.
13. Collins, N. D., G. C. Newbound, B. Albrecht, J. L. Beard, L. Ratner, and M. D. Lairmore. 1998. Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood 91:4701-1707.
14. Delamarre, L., A. R. Rosenberg, C. Pique, D. Pham, and M. C. Dokhelar. 1997. A novel human T-leukemia virus type 1 cell-to-cell transmission assay permits definition of SU glycoprotein amino acids important for infectivity. J. Virol. 71:259-266.
15. Delebecque, F., K. Pramberger, M. C. Prevost, M. Brahic, and F. Tangy. 2002. A chimeric human T-cell lymphotropic virus type 1 with the envelope glycoprotein of Moloney murine leukemia virus is infectious for murine cells. J. Virol. 76:7883-7889.
16. Derse, D., S. A. Hill, P. A. Lloyd, H. Chung, and B. A. Morse. 2001. Examining human T-lymphotropic virus type 1 infection and replication by cell-free infection with recombinant virus vectors. J. Virol. 75:8461-8468.
17. Derse, D., J. Mikovits, M. Polianova, B. K. Felber, and F. Ruscetti. 1995. Virions released from cells transfected with a molecular clone of human T-cell leukemia virus type 1 give rise to primary and secondary infections of T cells. J. Virol. 69:1907-1912.
18. Derse, D., J. Mikovits, and F. Ruscetti. 1997. X-I and X-II open reading frames of HTLV-I are not required for virus replication or for immortalization of primary T-cells in vitro. Virology 237:123-128.
19. Derse, D., J. Mikovits, D. Waters, S. Brining, and F. Ruscetti. 1996. Examining the molecular genetics of HTLV-I with an infectious molecular clone of the virus and permissive cell culture systems. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 12:1-5.
20. Gaudray, G., F. Caelum, J. Basbous, M. Biard-Piechaczyk, C. Devaux, and J. M. Mesnard. 2002. The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. J. Virol. 76:12813-12822.
21. Ghez, D., Y. Lepelletier, S. Lambert, J. M. Fourneau, V. Blot, S. Janvier, B. Arnulf, P. M. van Endert, N. Heveker, C. Pique, and O. Hermine. 2006. Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry. J. Virol. 80:6844-6854.
22. Goubau, P., M. Van Brussel, A. M. Vandamme, H. F. Liu, and J. Desmyter. 1994. A primate T-lymphotropic virus, PTLV-L, different from human T-lymphotropic viruses types I and II, in a wild-caught baboon (Papio hamadryas). Proc. Natl. Acad. Sci. USA 91:2848-2852.
23. Green, P. L., T. M. Ross, I. S. Chen, and S. Pettiford. 1995. Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation. J. Virol. 69:387-394.
24. rex production or virus replication and transformation. J. Virol. 64:4914-4921.
25. Guo, H. G., F. Wong-Stall, and R. C. Gallo. 1984. Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon. Science 223:1195-1197.
26. II is required for viral infectivity in vivo. J. Virol. 80:3469-3476.
27. Jassal, S. R., M. D. Lairmore, A. J. Leigh-Brown, and D. W. Brighty. 2001. Soluble recombinant HTLV-1 surface glycoprotein competitively inhibits syncytia formation and viral infection of cells. Virus Res. 78:17-34.
28. Jinno, A., Y. Haraguchi, H. Shiraki, and H. Hoshino. 1999. Inhibition of cell-free human T-cell leukemia virus type 1 infection at a postbinding step by the synthetic peptide derived from an ectodomain of the gp21 transmembrane glycoprotein. J. Virol. 73:9683-9689.
29. Jones, K. S., K. Fugo, C. Petrow-Sadowski, Y. Huang, D. C. Bertolette, I. Lisinski, S. W. Cushman, S. Jacobson, and F. W. Ruscetti. 2006. Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 use different receptor complexes to enter T cells. J. Virol. 80:8291-8302.
30. + T cells. J. Virol. 79:12692-12702.
31. Kim, F. J., N. Manel, Y. Boublik, J. L. Battini, and M. Sitbon. 2003. Human T-cell leukemia virus type 1 envelope-mediated syncytium formation can be activated in resistant mammalian cell lines by a carboxy-terminal truncation of the envelope cytoplasmic domain. J. Virol. 77:963-969.
32. Kimata, J. T., F. H. Wong, J. J. Wang, and L. Ratner. 1994. Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones. Virology 204:656-664.
33. Li, Q. X., D. Camerini, Y. Xie, M. Greenwald, D. R. Kuritzkes, and I. S. Chen. 1996. Syncytium formation by recombinant HTLV-II envelope glycoprotein. Virology 218:279-284.
34. Manel, N., F. J. Kim, S. Kinet, N. Taylor, M. Sitbon, and J. L. Battini. 2003. The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell 115:449-459.
35. Meertens, L., S. Chevalier, R. Weil, A. Gessain, and R. Mahieux. 2004. A 10-amino acid domain within HTLV-1 and HTLV-2 Tax protein sequences is responsible for their divergent subcellular localization. J. Biol. Chem. 279:43307-43320.
36. Meertens, L., and A. Gessain. 2003. Divergent simian T-cell lymphotropic virus type 3 (STLV-3) in wild-caught Papio hamadryas papio from Senegal: widespread distribution of STLV-3 in Africa. J. Virol. 77:782-789.
37. Meertens, L., R. Mahieux, P. Mauclere, J. Lewis, and A. Gessain. 2002. Complete sequence of a novel highly divergent simian T-cell lymphotropic virus from wild-caught red-capped mangabeys (Cercocebus torquatus) from Cameroon: a new primate T-lymphotropic virus type 3 subtype. J. Virol. 76:259-268.
38. Miyauchi, M., and K. Maruyama. 1990. Morphological and antigenic variations of human T cell leukemia virus type 1 particles in human lymphocytes. J. Electron Microsc. (Tokyo) 39:145-154.
39. Nicol, C., T. Astier-Gin, E. Edouard, E. Legrand, D. Moynet, A. Vital, D. Londos-Gagliardi, J. P. Moreau, and B. Guillemain. 1993. Establishment of HTLV-I-infected cell lines from French, Guianese and West Indian patients and isolation of a proviral clone producing viral particles. Virus Res. 30:317-334.
40. Nicot, C., M. Dundr, J. M. Johnson, J. R. Fullen, N. Alonzo, R. Fukumoto, G. L. Princler, D. Derse, T. Misteli, and G. Franchini. 2004. HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat. Med. 10:197-201.
41. Nicot, C., R. L. Harrod, V. Ciminale, and G. Franchini. 2005. Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions. Oncogene 24:6026-6034.
42. Ohsugi, T., T. Kumasaka, and T. Urano. 2004. Construction of a full-length human T cell leukemia virus type I genome from MT-2 cells containing multiple defective proviruses using overlapping polymerase chain reaction. Anal. Biochem. 329:281-288.
43. Poiesz, B. J., F. W. Ruscetti, A. F. Gazdar, P. A. Bunn, J. D. Minna, and R. C. Gallo. 1980. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl. Acad. Sci. USA 77:7415-7419.
44. Poiesz, B. J., F. W. Ruscetti, M. S. Reitz, V. S. Kalyanaraman, and R. C. Gallo. 1981. Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sezary T-cell leukaemia. Nature 294:268-271.
45. Quinnan, G. V., Jr., M. A. Wells, A. E. Wittek, M. A. Phelan, R. E. Mayner, S. Feinstone, R. H. Purcell, and J. S. Epstein. 1986. Inactivation of human T-cell lymphotropic virus, type III by heat, chemicals, and irradiation. Transfusion 26:481-483.
46. Robek, M. D., and L. Ratner. 2000. Immortalization of T lymphocytes by human T-cell leukemia virus type 1 is independent of the Tax-CBP/p300 interaction. J. Virol. 74:11988-11992.
47. Robek, M. D., F. H. Wong, and L. Ratner. 1998. Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytes. J. Virol. 72:4458-4462.
48. Seiki, M., S. Hattori, Y. Hirayama, and M. Yoshida. 1983. Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. Proc. Natl. Acad. Sci. USA 80:3618-3622.
49. Shimotohno, K., D. W. Golde, M. Miwa, T. Sugimura, and I. S. Chen. 1984. Nucleotide sequence analysis of the long terminal repeat of human T-cell leukemia virus type II. Proc. Natl. Acad. Sci. USA 81:1079-1083.
50. Shimotohno, K., Y. Takahashi, N. Shimizu, T. Gojobori, D. W. Golde, I. S. Chen, M. Miwa, and T. Sugimura. 1985. Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene. Proc. Natl. Acad. Sci. USA 82:3101-3105.
51. Shimotohno, K., W. Wachsman, Y. Takahashi, D. W. Golde, M. Miwa, T. Sugimura, and I. S. Chen. 1984. Nucleotide sequence of the 3′ region of an infectious human T-cell leukemia virus type II genome. Proc. Natl. Acad. Sci. USA 81:6657-6661.
52. Silverman, L. R., A. J. Phipps, A. Montgomery, L. Ratner, and M. D. Lairmore. 2004. Human T-cell lymphotropic virus type 1 open reading frame 11-encoded p30II is required for in vivo replication: evidence of in vivo reversion. J. Virol. 78:3837-3845.
53. Slamon, D. J., M. F. Press, L. M. Souza, D. C. Murdock, M. J. Cline, D. W. Golde, J. C. Gasson, and I. S. Chen. 1985. Studies of the putative transforming protein of the type 1 human T-cell leukemia virus. Science 228:1427-1430.
54. Slamon, D. J., K. Shimotohno, M. J. Cline, D. W. Golde, and I. S. Chen. 1984. Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV-II. Science 226:61-65.
55. Switzer, W. M., S. H. Qari, N. D. Wolfe, D. S. Burke, T. M. Folks, and W. Heneine. 2006. Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis. J. Virol. 80:7427-7438.
56. Takemura, T., M. Yamashita, M. K. Shimada, S. Ohkura, T. Shotake, M. Ikeda, T. Miura, and M. Hayami. 2002. High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons. J. Virol. 76:1642-1648.
57. Van Brussel, M., P. Goubau, R. Rousseau, J. Desmyter, and A. M. Vandamme. 1996. The genomic structure of a new simian T-lymphotropic virus, STLV-PH969, differs from that of human T-lymphotropic virus types I and II. J. Gen. Virol. 77:347-358.
58. Van Dooren, S., L. Meertens, P. Lemey, A. Gessain, and A. M. Vandamme. 2005. Full-genome analysis of a highly divergent simian T-cell lymphotropic virus type I strain in Macaca arctoides. J. Gen. Virol. 86:1953-1959.
59. Van Dooren, S., V. Shanmugam, V. Bhullar, B. Parekh, A. M. Vandamme, W. Heneine, and W. M. Switzer. 2004. Identification in gelada baboons (Theropithecus gelada) of a distinct simian T-cell lymphotropic virus type 3 with a broad range of Western blot reactivity. J. Gen. Virol. 85:507-519.
60. Vincent, M. J., F. J. Novembre, V. F. Yamshchikov, H. M. McClure, and R. W. Compans. 1996. Characterization of a novel baboon virus closely resembling human T-cell leukemia virus. Virology 226:57-65.
61. Wang, B., M. G. Agadjanyan, V. Srikantan, K. E. Ugen, W. Hall, M. H. Kaplan, K. Dang, W. V. Williams, and D. B. Weiner. 1993. Molecular cloning, expression, and biological characterization of an HTLV-II envelope glycoprotein: HIV-1 expression is permissive for HTLV-II-induced cell fusion. AIDS Res. Hum. Retrovir. 9:849-860.
62. Wirtz, R., and M. Lochelt. 2005. Construction and analysis of genomic, full-length infectious foamy virus DNA clones. Methods Mol. Biol. 304:423- 434.
63. Wolfe, N. D., W. Heneine, J. K. Carr, A. D. Garcia, V. Shanmugam, U. Tamoufe, J. N. Torimiro, A. T. Prosser, M. Lebreton, E. Mpoudi-Ngole, F. E. McCutchan, D. L. Birx, T. M. Folks, D. S. Burke, and W. M. Switzer. 2005. Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters. Proc. Natl. Acad. Sci. USA 102:7994-7999.
64. Xie, L., B. Yamamoto, A. Haoudi, O. J. Semmes, and P. L. Green. 2006. PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo. Blood 107:1980-1988.
65. Ye, J., L. Xie, and P. L. Green. 2003. Tax and overlapping Rex sequences do not confer the distinct transformation tropisms of human T-cell leukemia virus types 1 and 2. J. Virol. 77:7728-7735.
66. Younis, I., B. Yamamoto, A. Phipps, and P. L. Green. 2005. Human T-cell leukemia virus type 1 expressing nonoverlapping Tax and Rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo. J. Virol. 79:14473-14481.
67. Zemba, M., A. Alke, J. Bodem, I. G. Winkler, R. L. Flower, K. Pfrepper, H. Delius, R. M. Flugel, and M. Lochelt. 2000. Construction of infectious feline foamy virus genomes: cat antisera do not cross-neutralize feline foamy virus chimera with serotype-specific Env sequences. Virology 266:150-156.
68. Zhao, T. M., M. A. Robinson, F. S. Bowers, and T. J. Kindt. 1995. Characterization of an infectious molecular clone of human T-cell leukemia virus type I. J. Virol. 69:2024-2030.