Immortalization of T lymphocytes by human T-cell leukemia virus type 1 is independent of the tax-CBP/p300 interaction

Journal of Virology

Volumn 74, Issue 24, 2000, Pages 11988-11992

  Robek, M D ^a   Ratner, L ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN P300; TAX PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; VIRUS PARTICLE; VIRUS REPLICATION;

CELL LINE; CELL TRANSFORMATION, VIRAL; CREB-BINDING PROTEIN; GENE EXPRESSION REGULATION, VIRAL; GENES, PX; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; NUCLEAR PROTEINS; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 0034466905     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.24.11988-11992.2000     Document Type: Article

References (62)

1. p300 and p300-associated proteins, are components of TATA-binding protein (TBP) complexes
2. Distinct regions in human T-cell lymphotropic virus type I Tax mediate interactions with activator protein CREB and basal transcription factors
3. E1-A associated p300 and CREB-associated CBP belong to a conserved family of coactivators
4. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor
5. Recruitment of p300/CBP in p53-dependent signal pathways
6. The SV40 large T antigen and adenovirus E1A oncoproteins interact with distinct isoforms of the transcriptional coactivator p300
7. HTLV-1 tax induces cellular proteins that activate the κB element in the IL-2 receptor alpha gene
8. The CBP coactivator is a histone acetyltransferase
9. Stimulation of c-jun activity by CBP: C-jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro
10. Genetic characterization of transactivation of the human T-cell leukemia virus type 1 promoter: Binding of Tax to Tax-responsive element I is mediated by the cyclic AMP-responsive members of the CREB/ATF family of transcription factors
11. Function of the human T-cell leukemia virus type 1 21-base-pair repeats in basal transcription
12. Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300
13. Modulation of Tax and PKA-mediated expression of HTLV-I promoter via cAMP response element binding and modulator proteins CREB and CREM
14. A molecular mechanism for human T-cell leukemia virus latency and Tax transactivation
15. Identification of the gene responsible for human T-cell leukemia virus transcriptional regulation
16. Phosphorylated CREB binds specifically to the nuclear protein CBP
17. The human T-cell leukemia virus type 1 oncoprotein Tax inhibits the transcriptional activity of c-Myb through competition for the CREB binding protein
18. CBP as a transcriptional coactivator of c-myb
19. Characterization of monoclonal antibodies raised against p300: Both p300 and CBP are present in intracellular TBP complexes
20. Molecular cloning and functional analysis of the adenovirus E1A-associated 300 kD (p300) protein reveals a protein with properties of a transcriptional adaptor
21. Association of p300 and CBP with simian virus 40 large T antigen
22. The pX protein of HTLV-1 is a transcriptional transactivator of its long terminal repeats
23. SRF causes the aberrant induction of cellular immediate early genes through CArG boxes
24. CREB-binding protein/p300 are transcriptional coactivators of p65
25. Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: A molecular mechanism of Tax transactivation
26. Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I
27. Synergistic activation of transcription by CBP and p53
28. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
29. An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300
30. P300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax and a multi-histone acetyltransferase/activator-enhancer complex
31. Adult T-cell leukemia antigen in an ATL cell line and detection of antibodies to the antigen in human sera
32. Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1
33. Transcriptional (p40X) and post transcriptional (p27X-III) regulators are required for the expression and replication of human T-cell leukemia virus type I
34. PCAF interacts with tax and stimulates tax transactivation in a histone-acetyltransferase-independent manner
35. The coactivator CBP stimulates human T-cell lymphotropic virus type 1 Tax transactivation in vitro
36. Adaptor mediated recruitment of RNA polymerase II to a signal-dependent activator
37. Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones
38. Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP
39. Nuclear protein CBP is a coactivator for the transcription factor CREB
40. Development and characterization of monoclonal antibodies to the HTLV-1 Tax (p40X) protein
41. Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding to the viral promoter
42. HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor
43. Binding and modulation of p53 by p300/CBP coactivators
44. RNA helicase A mediates association of CBP with RNA polymerase II
45. Interaction of the co-activator CBP with Myb proteins: Effects of Myb-specific transactivation and on the cooperativity with NF-M
46. The transcriptional coactivators p300 and Cbp are histone acetyltransferases
47. Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator
48. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
49. The human T-lymphotropic virus type 1 tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells
50. + T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone
51. Direct evidence that the p40x of human T-cell leukemia virus type-1 is a trans-activating transcriptional transactivator
52. Identification of HTLV-1 tax transactivator mutants exhibiting novel transcriptional phenotypes
53. A transactivator Tax of human T-cell leukemia virus type 1 binds to NF-κB p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-κB site and CArG box
54. Oncogenic transformation by the tax gene of human T-cell leukemia virus type 1 in vitro
55. Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat
56. The Tax protein of human T-cell leukemia virus type i mediates the transactivation of the c-sis/platelet-derived growth factor-B promoter through interactions with the zinc finger transcription factors Sp1 and NGFI-A/Egr-1
57. Binding of p53 to the KIX domain of CREB binding protein: A potential link to human T-cell leukemia virus type 1-associated leukemogenesis
58. Binding of the human T-cell leukemia virus Tax protein to the coactivator CBP interferes with CBP-mediated transcriptional control
59. Molecular interactions between the coactivator CBP and the human T-cell leukemia virus Tax protein
60. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
61. Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats
62. Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type 1 Tax and CREB