Role of gamma interferon and interleukin-4 in host defense against the human filarial parasite Brugia malayi

Infection and Immunity

Volumn 68, Issue 5, 2000, Pages 3034-3035

  Babu, Subash ^a   Ganley, Lisa M ^a   Klei, Thomas R ^b   Shultz, Leonard D ^c   Rajan, T V ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRUGIA MALAYI; CORRELATION FUNCTION; CYTOKINE PRODUCTION; FILARIASIS; HOST RESISTANCE; IMMUNE RESPONSE; MOUSE; NONHUMAN; PARASITE DEVELOPMENT; PRIORITY JOURNAL;

ANIMALS; BRUGIA MALAYI; DISEASE MODELS, ANIMAL; ELEPHANTIASIS, FILARIAL; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, SCID;

EID: 0034059455     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.5.3034-3035.2000     Document Type: Article

References (4)

1. Lawrence, R. A., J. E. Allen, W. F. Gregory, M. Kopf, and R. M. Maizels. 1995. Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J. Immunol. 154:5995-6001.
2. Ottesen, E. A., B. O. Duke, M. Karam, and K. Behbehani. 1997. Strategies and tools for the control/elimination of lymphatic filariasis. Bull. W. H. O. 75:491-503.
3. Reiner, S. L., and R. M. Locksley. 1495. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151-177.
4. Yates, J. A., K. A. Schmitz, F. K. Nelson, and T. V. Rajan. 1994. Inactivity and normal development of third stage Brugia malayi maintained in vitro. J. Parasitol. 80:891-894.