Increased hepatitis B surface antigen production by recombinant Aspergillus niger through the optimization of agitation and dissolved oxygen concentration

Applied Microbiology and Biotechnology

Volumn 75, Issue 2, 2007, Pages 279-288

  James, Emmanuel R ^a   Van Zyl, Willem H ^a   Görgens, Johann F ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

A. niger; Agitation intensity; Dissolved oxygen concentration; HBsAg; VLP production

Indexed keywords

BIOREACTORS; DISEASES; DISSOLVED OXYGEN; OPTIMIZATION; VIRUSES;

AGITATION INTENSITY; DISSOLVED OXYGEN CONCENTRATION; RESPONSE SURFACE METHODOLOGY (RSM); VLP PRODUCTION;

ANTIGENS;

DISSOLVED OXYGEN; HEPATITIS B SURFACE ANTIGEN;

ANTIGEN; BIOMASS; CONCENTRATION (COMPOSITION); DISSOLVED OXYGEN; FUNGUS; HEPATITIS; MODEL VALIDATION; MORPHOLOGY; OPTIMIZATION; PROTEIN; REACTION KINETICS; RECOMBINATION;

ARTICLE; ASPERGILLUS NIGER; BACTERIUM CULTURE; BIOMASS; BIOREACTOR; MORPHOLOGY; NONHUMAN; RESPONSE SURFACE METHOD; VIRUS LIKE AGENT;

ASPERGILLUS NIGER; BIOMASS; BIOREACTORS; BIOTECHNOLOGY; CULTURE MEDIA; HEPATITIS B SURFACE ANTIGENS; OXYGEN; RECOMBINANT PROTEINS;

ASPERGILLUS NIGER; FUNGI;

EID: 34249889862     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-006-0812-9     Document Type: Article

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