Multiple fungal enzymes possess cysteine synthase activity in vitro

Research in Microbiology

Volumn 158, Issue 5, 2007, Pages 428-436

  Brzywczy, Jerzy ^a   Natorff, Renata ^a   Sieńko, Marzena ^a   Paszewski, Andrzej ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Aspergillus nidulans; Cross pathway regulation; Cysteine synthase; Regulation; Sulfur amino acid synthesis

Indexed keywords

ARGININE; CYSTEINE SYNTHASE; FUNGAL ENZYME; HISTIDINE; HOMOCYSTEINE SYNTHETASE; PROLINE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS NIDULANS; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN MALNUTRITION; SCHIZOSACCHAROMYCES POMBE;

ARGININE; ASPERGILLUS NIDULANS; BLOTTING, NORTHERN; CARBON-OXYGEN LYASES; CATALYSIS; CYSTEINE; CYSTEINE SYNTHASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; HISTIDINE; MODELS, BIOLOGICAL; MUTATION; PHYLOGENY; PROLINE; SERINE; SULFATES;

EMERICELLA NIDULANS; FUNGI; SCHIZOSACCHAROMYCES POMBE;

EID: 34249880807     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/j.resmic.2007.03.002     Document Type: Article

References (35)

1. Alexander F.W., Sandmeier E., Mehta P.K., and Christen P. Evolutionary relationships among pyridoxal-5′-phosphate-dependent enzymes. Regio-specific α, β and γ families. Eur. J. Biochem. 219 (1994) 953-960
2. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403-410
3. Berse B., Dmochowska A., Skrzypek M., We{ogonek}gleński P., Bates M.A., and Weiss R.L. Cloning and characterization of the ornithine carbamoyltransferase gene from Aspergillus nidulans. Gene 25 (1983) 109-117
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
5. Brzywczy J., and Paszewski A. Role of O-acetyhomoserine sulfhydrylase in sulfur amino acid synthesis in various yeasts. Yeast 9 (1993) 1335-1342
6. Brzywczy J., and Paszewski A. Sulfur amino acid metabolism in Schizosaccharomyces pombe: occurrence of two O-acetylhomoserine sulfhydrylases and the lack of the reverse transsulfuration pathway. FEMS Microbiol. Lett. 121 (1994) 171-174
7. Brzywczy J., Sieńko M., Kucharska A., and Paszewski A. Sulfur amino acid synthesis in Schizosaccharomyces pombe represents a specific variant of sulfur metabolism in fungi. Yeast 19 (2002) 29-35
8. Chomczyński P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. BioTechniques 15 (1993) 532-537
9. Clutterbuck A.J. Linkage map and locus list. Prog. Indust. Microbiol. 29 (1994) 791-824
10. Cove D.J. The induction and repression of nitrate reductase in the fungus Aspergillus nidulans. Biochim. Biophys. Acta 113 (1966) 51-56
11. Cybis J., Piotrowska M., and We{ogonek}gleński P. Genetic control of the arginine pathways in Aspergillus nidulans. Common regulation of anabolism and catabolism. Mol. Gen. Genet. 118 (1972) 273-277
12. Cybis J., Natorff R., Lewandowska I., Prażmo W., and Paszewski A. Mutation affecting cysteine synthesis in Aspergillus nidulans: characterization and chromosome mapping. Genet. Res. Camb. 51 (1988) 85-88
13. Felsenstein J. PHYLIP - Phylogeny Inference Package (Version 3.2). Cladistics 5 (1989) 164-166
14. Fujita Y., and Takegawa K. Characterization of two genes encoding putative CS required for cysteine biosynthesis in Schizosaccharomyces pombe. Biosci. Biotechnol. Biochem. 68 (2004) 306-311
15. Fujita Y., Ukena E., Iefuji H., Giga-Hama Y., and Takegawa K. Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs. Microbiology 152 (2006) 397-404
16. Hoffmann B., Valerius O., Andermann M., and Braus G.H. Transcriptional autoregulation and inhibition of mRNA translation of amino acid regulator gene cpcA of filamentous fungus Aspergillus nidulans. Mol. Biol. Cell 12 (2001) 2846-2857
17. Martinelli S.D. Gene symbols. Prog. Indust. Microbiol. 29 (1994) 825-833
18. Morzycka E., and Paszewski A. Two pathways of cysteine biosynthesis in Saccharomycopsis lipolytica. FEBS Lett. 101 (1979) 97-100
19. Natarajan K., Meyer M.R., Jackson B.M., Slade D., Roberts C., Hinnenbush A.G., and Marton M.J. Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell. Biol. 21 (2001) 4347-4368
20. Natorff R., Sieńko M., Brzywczy J., and Paszewski A. The Aspergillus nidulans metR gene encodes a bZIP protein which activates transcription of sulphur metabolism genes. Mol. Microbiol. 49 (2003) 1081-1094
21. Page R.D.M. TREEVIEW: An application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12 (1996) 357-358
22. Paszewski A., and Grabski J. Studies on β-cystathionase and O-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans. Acta Biochim. Polon. 20 (1973) 159-168
23. Paszewski A., and Grabski J. Regulation of S-amino acids biosynthesis in Aspergillus nidulans. Mol. Gen. Genet. 132 (1974) 307-320
24. Paszewski A., and Grabski J. Enzymatic lesions in methionine mutants of Aspergillus nidulans: role and regulation of an alternative pathway for cysteine and methionine synthesis. J. Bacteriol. 124 (1975) 893-904
25. Paszewski A., Prażmo W., Nadolska J., and Regulski M. Mutations affecting the sulfur assimilation pathway in Aspergillus nidulans: their effect on sulfur amino acid metabolism. J. Gen. Microbiol. 130 (1984) 1113-1121
26. Pienia{ogonek}żek N.J., Bal J., Balbin E., and Ste{ogonek}pień P.P. An Aspergillus nidulans mutant lacking serine transacetylase: evidence for two pathways of cysteine biosynthesis. Mol. Gen. Genet. 132 (1974) 363-366
27. Pienia{ogonek}żek N.J., Ste{ogonek}pień P.P., and Paszewski A. An Aspergillus nidulans mutant lacking cystathionine β-synthase: identity of l-serine sulfhydrylase and its distinctness from O-acetyl-l-serine sulfhydrylase. Biochim. Biophys. Acta 297 (1973) 37-47
28. Piotrowska M. Cross-pathway regulation of ornithine carbamoyltransferase synthesis in Aspergillus nidulans. J. Gen. Microbiol. 116 (1980) 335-339
29. Piotrowska M., Kruszewska A., and Paszewski A. Effect of regulatory mutations of sulfur metabolism on the levels of cysteine and homocysteine synthesizing enzymes in Neurospora crassa. Acta Biochim. Polon. 27 (1980) 395-403
30. Thomas D., and Surdin-Kerjan Y. Metabolism of sulfur amino acids in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 61 (1997) 503-532
31. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24 (1997) 4876-4882
32. Topczewski J., Sieńko M., and Paszewski A. Cloning and characterization of the Aspergillus nidulans cysB gene encoding cysteine synthase. Curr. Genet. 31 (1997) 348-356
33. Treichler H.J., Liersch M., Nüesch J., and Dobelli H. In: Sebek O.K., and Laskin A.I. (Eds). Genetics of Industrial Microorganisms (1979), American Society for Microbiology, Washington, DC 97-104
34. Warrilow A.G.S., and Hawkesford M.J. Cysteine synthase (O-acetylserine (thiol) lyase) substrate specificities classify the mitochondral isoform as a cyanoalanine synthase. J. Exp. Bot. 51 (2000) 985-993
35. Yelton M.M., Timberlake W.E., and van den Hondel C.A.M.J.J. A cosmid for selecting genes by complementation in Aspergillus nidulans: selection of the developmentally regulated yA locus. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 834-838